Effect of estradiol-17β on collagen biosynthesis, degradation and re-utilization in vivo

Henneman, Dorothy H.

doi:10.1016/0006-291x(71)90603-6

Cited by 18 publications

(3 citation statements)

References 6 publications

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“…They could therefore be responsible for the rhythmicities evident at the structural and chemical levels. Pituitary hormones, for instance, promote collagen cross-link formation [50] but estrogens (mg range in rats and guinea pigs) produce an abnormal collagen with a high proline to hydroxyproline ratio which may be deficient in cross-link [51,52]. Estrogen in rabbits stimulates osteoid formation within osteocyte lacunae (ca.…”

Section: Physiological Basis For Dentin Rhythmsmentioning

confidence: 99%

Rhythmic dentinogenesis in the rabbit incisor: Circadian, ultradian, and infradian periods

Rosenberg

Simmons

1980

Calcif Tissue Int

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Summary.We have identified a variety of biological rhythms involved in the apposition and mineralization of dentin in the rabbit incisor.Animals were injected during the day or night with lead acetate at 2-week intervals--to provide biological time markers in forming dentin--and transverse undecalcified sections of the lower incisors were prepared for electron microprobe analysis. The positions of the lead markers were identified, and the continuous distribution of calcium and sulfur was measured at 1 /xm intervals between the markers. In thin sections stained with hematoxylin after decalcification, the widths of a series of structural increments (bands) were measured with an ocular micrometer.Fourier analysis of the data revealed spectra of structural and compositional rhythms with a range of periodicities which extended from a matter of hours [ultradian (< 24 h)] to days [infradian (> 24 h) and circadian (approximately 24 h)].The structural and compositional rhythms appeared to be independent to the extent that they did not necessarily have the same periods, or amplitudes. Nor were there simple phase relationships between all of the rhythms. At some times, Ca and S fluctuations are inversely proportional (180 ~ out of phase), but in other cases they are directly proportional or out of phase by varying degrees other than 180 ~ . The analyses thus suggest that calcium and sulfur deposition (representing mineral and glycosaminoglycan deposition, respectively) are not simply inversely proportional, and that the hematoxylin-stained structural increments did not solely reflect differences in the distribution of the mineral components in dentin.Send ofll)rint requests to Dr. Gary D. Rosenberg, at the above address

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Section: Physiological Basis For Dentin Rhythmsmentioning

confidence: 99%

Rhythmic dentinogenesis in the rabbit incisor: Circadian, ultradian, and infradian periods

Rosenberg

Simmons

1980

Calcif Tissue Int

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“…Sex steroids, including estrogens and androgens, affect not only the sex differentiation of reproductive tissues but also various non‐reproductive tissues including skin. In humans, topical application of oestrogen to the skin enhances the synthesis of dermal elastic fibres, dermal extracellular matrix components, subcutaneous fat deposition, and stimulates blood flow in the skin (Braverman & Fonferko, 1982; Henneman, 1971; Surazynski et al ., 2003). In this study, the categories of KEGG pathway enrichment with the top two significance for female‐biased genes were extracellular matrix (ECM)‐receptor interactions and focal adhesions.…”

Section: Discussionmentioning

confidence: 99%

Comparative transcriptome analysis reveals sex bias in expression patterns of genes related to sex steroids and immunity in the skin of spinyhead croaker Collichthys lucidus

Zhou

Liu

Chen

et al. 2023

Journal of Fish Biology

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Fish skin is the first barrier against external invasion, and also an important interface for communication between males and females during reproduction. Nonetheless, sexual dimorphism in the physiology of fish skins is still poorly understood. Herein, transcriptomes of skin were comparatively analysed between males and females in spinyhead croaker, Collichthys lucidus. Totally, 170 differentially expressed genes (DEG) were detected, including 79 female‐biased genes and 91 male‐biased genes. Gene ontology (GO) annotation items of the DEGs were mainly enriched in biological process items (86.2%), including regulation of biological processes, responses to chemical and biological stimuli, transport and secretion, movement, immune response, tissue development, etc. In KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway enrichment analysis, the male‐biased genes were enriched in pathways including those related to immunity such as the TNF signalling pathway and IL‐17 signalling pathway, whereas the female‐biased genes were enriched in pathways including those related to female steroids such as ovarian steroidogenesis and oestrogen signalling pathway. In addition, odf3 was found to be a male‐specific expression gene, being a candidate marker for phenotypic sex. Thus, the sexual difference in gene expression in fish skin in spawning season was uncovered by transcriptome analysis for the first time, providing new insights into sexual dimorphism in the physiology and functions of fish skin.

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“…The effects of estradiol are, however, notably tissue-and species-dependent. Treatment of rats (Skosey and Damgaard, 1973) and guinea pigs (Henneman, 1971) with estradiol down-regulated collagen biosynthesis in skin, resulting in less total skin mass.…”

Section: Discussionmentioning

confidence: 99%

Collagen characteristics of skin, fell, and epimysium from rams, wethers, and zeranol-implanted ram lambs

Maiorano

McCormick

et al. 1995

Journal of Animal Science

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Eighteen spring-born Columbia ram, wether, and zeranol-implanted ram lambs were examined to determine the influence of castration or zeranol implantation on collagen characteristics of skin, fell, and epimysium and possible relationships between collagen properties of each tissue and difficulty of pelt removal. Pelt removal force was lower in wethers than in rams (P < .05) and intermediate for zeranol-implanted rams. Collagen concentration in skin of rams was greater (P < .05) than that in wethers or implanted rams, but percentage of heat-soluble collagen in skin was higher in implanted rams. Percentage of type III collagen in skin was highest in rams and lowest in wethers (P < .05); that in the skin of implanted rams was intermediate. The fell of wethers contained a higher (P < .05) collagen concentration, higher insoluble collagen amount, and lower percentage of soluble collagen than that of rams or implanted rams. The fell had a lower percentage of type III collagen than that of rams (P < .05). Epimysium collagen concentration of rams and wethers was higher (P < .05) than that of implanted rams; however, percentage of soluble collagen was higher for the implanted rams than for the other classes. Type III collagen percentage in the epimysium did not differ by animal class (P < .05). Zeranol-implanted ram lambs had a higher percentage of soluble collagen in all tissues examined than did non-implanted rams and force required for pelt removal was reduced in implanted rams.(ABSTRACT TRUNCATED AT 250 WORDS)

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Effect of estradiol-17β on collagen biosynthesis, degradation and re-utilization in vivo

Cited by 18 publications

References 6 publications

Rhythmic dentinogenesis in the rabbit incisor: Circadian, ultradian, and infradian periods

Rhythmic dentinogenesis in the rabbit incisor: Circadian, ultradian, and infradian periods

Comparative transcriptome analysis reveals sex bias in expression patterns of genes related to sex steroids and immunity in the skin of spinyhead croaker Collichthys lucidus

Collagen characteristics of skin, fell, and epimysium from rams, wethers, and zeranol-implanted ram lambs

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