2021
DOI: 10.23876/j.krcp.20.210
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Effect of estimating equations for glomerular filtration rate on novel surrogate markers for renal outcome

Abstract: Backgrounds: Recently, alternative surrogate endpoints such as a 30% or 40% decline in estimated glomerular filtration rate (eGFR) or eGFR slope over 2 to 3 years have been proposed for predicting renal outcomes. However, the impact of GFR estimation methods on the accuracy and effectiveness of surrogate markers is unknown. Methods: We retrospectively enrolled participants in health screening programs at three hospitals from 1995 to 2009. We defined two different participant groups as YR1 and YR3, which had av… Show more

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“…Thus, understanding the progressive course of the decline of kidney function is a must to help prevent DKD progression to KF and reduce patient mortality. Physicians should also be aware of the eGFR as an indicator of kidney function and the importance of evaluating and utilizing it for proper disease management [ 12 ].…”
Section: Introductionmentioning
confidence: 99%
“…Thus, understanding the progressive course of the decline of kidney function is a must to help prevent DKD progression to KF and reduce patient mortality. Physicians should also be aware of the eGFR as an indicator of kidney function and the importance of evaluating and utilizing it for proper disease management [ 12 ].…”
Section: Introductionmentioning
confidence: 99%