Effect of Essential Oil and Chlorhexidine Mouthwashes on Gingival Fibroblast Survival and Migration

Abstract

The results of this in vitro study indicate that diluted EO displayed no detectable detrimental effects on human gingival and PDL fibroblasts, whereas diluted CHX reduced both cell migration and long-term survival. Both solutions retained their antimicrobial activity in lower concentrations.

Short-term effects of scaling and root planing with or without adjunctive use of an essential-oil-based mouthwash in the treatment of periodontal inflammation in smokers

“…However, an interesting fi nding was that SRP + essential-oil mouthwash use reduced periodontal infl ammation to a much greater extent as compared to when SRP was used alone to treat periodontal disease in smokers. It is pertinent to mention that essential-oil-based antiseptics are a mixture of the phenol related essential oils, including thymol (0.060%), eucalyptol (0.091%), menthol (0.042%), and methylsalicylate (0.064%) in a 26.9% hydroalcoholic vehicle [13]. Essential-oil-based mouthwashes have been reported to denature bacterial membrane protein and inhibiting bacterial enzyme action [13].…”

“…It is pertinent to mention that essential-oil-based antiseptics are a mixture of the phenol related essential oils, including thymol (0.060%), eucalyptol (0.091%), menthol (0.042%), and methylsalicylate (0.064%) in a 26.9% hydroalcoholic vehicle [13]. Essential-oil-based mouthwashes have been reported to denature bacterial membrane protein and inhibiting bacterial enzyme action [13]. Moreover, essential-oil-based mouthwashes present anti-infl ammatory and prostaglandin synthetase inhibitor activity, which can occur at concentrations lower than that needed for antibacterial activity [13].…”

“…Essential-oil-based mouthwashes have been reported to denature bacterial membrane protein and inhibiting bacterial enzyme action [13]. Moreover, essential-oil-based mouthwashes present anti-infl ammatory and prostaglandin synthetase inhibitor activity, which can occur at concentrations lower than that needed for antibacterial activity [13]. Although the present results showed SRP + essential-oil-based mouthwash to be more eff ective in reducing periodontal disease, it is important to note that these oral rinses have not been proven to enhance the healing of gingival tissues after periodontal surgery.…”

Impact of scaling and root planing with adjunct essential-oil-based mouthwash usage on whole salivary IgG levels in patients with periodontal inflammation

“…This refl ects that EOBM exerts an anti-infl ammatory eff ect, thereby enhancing the overall effi cacy of SRP. It has been reported that EOBM denatures bacterial membrane protein and inhibits bacterial enzyme action [15]. Moreover, EOBM presents anti-infl ammatory and prostaglandin synthetase inhibitor activity, which can occur at concentrations lower than that needed for antibacterial activity [15].…”

“…It has been reported that EOBM denatures bacterial membrane protein and inhibits bacterial enzyme action [15]. Moreover, EOBM presents anti-infl ammatory and prostaglandin synthetase inhibitor activity, which can occur at concentrations lower than that needed for antibacterial activity [15]. Moreover, EOBM is also capable of extracting bacterial endotoxins that theoretically may reduce plaque pathogenicity [16].…”