Effect of Esophageal Variceal Sclerotherapy (EVS) on Lung Function

Pleuropulmonary complications of esophageal variceal sclerotherapy with absolute alcohol

“…However, a larger controlled study is required to study the effect of endoscopy and sclerotherapy on PaO 2 . No significant change was seen in pH or PaCO 2 in the present study (Table 2), which correlates with the studies by Korula et al 16 . and Bailey‐Newton et al 17 …”

“…There was no significant change in MMFR and PEFR after sclerotherapy in the present study (Table 3) as compared with baseline values. These observations are in accordance with those of Korula et al ., who used sodium tetradecyl sulfate as a sclerosant and showed no significant changes in PFT parameters after EVS 16 . Absolute alcohol was used in the present study.…”

“…Korula et al . studied 11 patients undergoing EVS and 11 controls undergoing endoscopy only and performed blood gas analysis, pulmonary function test (PFT), ventilation perfusion (V/Q) scan before and after the procedure and demonstrated no significant change in PaO 2 in either group 16 . Bailey‐Newton et al .…”

“…Korula et al studied 11 patients undergoing EVS and 11 controls undergoing endoscopy only and performed blood gas analysis, pulmonary function test (PFT), ventilation perfusion (V/Q) scan before and after the procedure and demonstrated no significant change in PaO 2 in either group. 16 Bailey-Newton et al studied eight patients undergoing sclerotherapy and observed that there was a fall in PaO 2 after sedation and introduction of the gastroscope, but there was no further fall after sclerotherapy. 17 Barkin et al studied 20 patients, out of which six had a fall in O 2 saturation (SaO 2 ) of ≥4% during endoscopy.…”

Respiratory function after injection sclerotherapy of oesophageal varices.

“…16 The patients in that study, however, were treated under diazepam and pethidine sedation. Both drugs are respiratory depressants; they have a comparatively long duration of action and both groups in that study showed a decrease in Pao2 postoperatively.…”