Abstract:Aim: Thyroidectomy is frequently associated with substantial
postoperative pain. Esketamine, an N-methyl-D-aspartate receptor
antagonist, has been demonstrated to be effective in multiple analgesia.
We hypothesized that intraoperative administration of esketamine may
reduce perioperative opioid consumption and postoperative pain in
patients undergoing thyroidectomy. Methods: Sixty patients undergoing
thyroidectomy were randomly assigned to two groups. Patients in the
saline group received a pre-incisional intr… Show more
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