2016
DOI: 10.1001/jama.2016.7635
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Effect of Escitalopram on All-Cause Mortality and Hospitalization in Patients With Heart Failure and Depression

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Cited by 247 publications
(194 citation statements)
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References 39 publications
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“…When treating the mentioned depressive and anxiety disorders, pharmacological treatment, especially using tricyclic antidepressants, should be restricted (due to side effects) to psychiatrically severe cases [20]. None of the methods tested in large population studies has shown clear evidence of its effectiveness in decreasing the risk of induction of cardiovascular disease by psychosomatic disorders or all-cause mortality or hospitalisation [19][20][21][22]. However, psychotherapy and psychopharmacological treatment in patients with at least moderate depression or anxiety seem to improve not only mental, but also physical health [19,20].…”
Section: Handling Of Psychosomatic Disorders In Cardiac Patientsmentioning
confidence: 99%
“…When treating the mentioned depressive and anxiety disorders, pharmacological treatment, especially using tricyclic antidepressants, should be restricted (due to side effects) to psychiatrically severe cases [20]. None of the methods tested in large population studies has shown clear evidence of its effectiveness in decreasing the risk of induction of cardiovascular disease by psychosomatic disorders or all-cause mortality or hospitalisation [19][20][21][22]. However, psychotherapy and psychopharmacological treatment in patients with at least moderate depression or anxiety seem to improve not only mental, but also physical health [19,20].…”
Section: Handling Of Psychosomatic Disorders In Cardiac Patientsmentioning
confidence: 99%
“…Dest ravaux plus récents nous montrentq ue les antidépresseurs utilisésc hez l'insuffisant cardiaque dépressif sont inefficaces sur la surmortalité cardiaque [57] mais également sur la dépression des patients et une autre méta-analyse nous démontrent même leur caractère potentiellement dangereux [58].…”
Section: La Prise En Chargeunclassified
“…On the other hand, SSRIs appear safe in treatment of depression in persons with heart failure [74]. However, in two randomised controlled trials, the antidepressant effect of SSRIs on depression in heart failure was not demonstrated to be better than placebo [74,75]. With regard to other antidepressant agents (e.g.…”
Section: Treatment Of Depression In Heart Failurementioning
confidence: 99%
“…This because traditional first line pharmacological treatment appears less effective [74,75] and a large treatment-demand gap has appeared due to a lack of psychotherapists [95]. As described in table 2 and in a recent meta-analysis [115] CBT has demonstrated promising results regarding depression for persons with heart failure.…”
Section: Rationale For the Thesismentioning
confidence: 99%
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