Effect of enhancement of uterine involution and earlier initiation of post-partum cyclicity on the reproductive performance of buffalo

Abstract

The aim of the present work was to study the effect of either gonadotrophin-releasing hormone (GnRH)-prostaglandin PGF2+/--GnRH (G-P-G) or equine chorionic gonadotrophin (eCG)-PGF2+/--GnRH (eCG-P-G) regimes with or without intramuscular injection of ergometrine maleate (Methergin) within 24 h post partum on the uterine involution, initiation of post partum cyclicity and subsequent reproductive performance of buffalo. A total of 60 parturient Egyptian buffalos (2-4 lactations) were used to conduct this study. The involved animals were allotted into two main groups (A and B), each with 30 animals, on the basis of whether buffalo cows received an i.m. injection of 3 mg of Methergin within the first 24 h post partum (A, Meth. T) or not (B, Meth. NT). Each main group was subdivided into three subgroups: A1, A2 and A3 in case of A and B1, B2 and B3 in case of B. The G-P-G regime was applied on both A1 (Meth. T) and B1 (Meth. NT) buffalos, where each individual received two i.m. injections of 0.020 mg GnRH analogue (buserelin) at Days 18 and 33 post partum with i.m. injection of 25 mg PGF2+/- (Dinoprost) in between at Day 25. The eCG-P-G regime was applied on both A2 (Meth. T) and B2 (Meth. NT) buffalos, where each individual received i.m. injection of 1000 IU eCG, 25 mg of PGF2+/- (Dinoprost) and 0.020 mg of GnRH analogue (buserelin) at Days 8, 18 and 25 post partum, respectively. The A3 subgroup (Meth. T, alone) was control for A1 and A2 subgroups and the B3 subgroup was the non-treated control for all subgroups. There was a significant (P< 0.01) decrease in the days required for complete uterine involution in subgroups A1, B1 and A3, indicating the enhancement of uterine involution. The post partum cyclicity was initiated earlier in all of the treatment regimes applied in the present study, as was indicated by significant (P < 0.01) decrease in the days to first ovulation in these subgroups compared with the non-treated control subgroup. The reproductive performance of treated buffalos improved as was shown by the significant (P < 0.01) decrease in days to first service, days open and calving interval. It is concluded that enhancement of uterine involution and/or earlier initiation of post-partum cyclicity improve the reproductive performance of buffalos.

Effect of exogenous oxytocin on the expression of oxytocin receptor gene and uterine involution in local Iraqi cows

“…As for the cervix diameter, the result showed a highly significant difference between the control group and the treated group during the first and second weeks, which agreed with the result obtained by Romoun et al (34). on the other hand, the third and fourth weeks did not significantly differ between the treated and control groups.…”

Prevention of Retention of Placenta in Lactating Friesian Cows with Dystocia and its Relation with their Productive and Reproductive Efficiency and Blood Constituents

“…The decreasing of calving interval of administrated groups was mainly related to decrease first estrus postpartum, service period and days open length as compared to untreated group (Table 3). Our results came in accordance with those of former studies (Ramoun et al, 2006, andAyman, 2013). PGF2α or oxytocin treated cows recorded the shortest calving interval compared to other treated or untreated cows (Waheeb-Reham et al, 2010).…”

“…These findings reflecting that treatment of exogenous OX,PG or MT to lactating Friesian cows within ½ hour postpartum is able to improve the reproductive efficiency, especially with PG or MT, which had recorded the highest improvement compared with that recorded for either oxytocintreated or control cows. Our results came in agreement with those of Ramoun et al (2006) and Nosier et al (2012) who demonstrated that cows treated with oxytocin and methylergometrin or PGF2α had improved in reproductive parameters when compared to untreated ones. Prostaglandin F2α administrated animals showed the highest improved productive and reproductive performance with economical return when compared with cows treated with other protocols (manual remove, oxytocin or carazolol), (Waheeb-Reham et al, 2010).…”

Reproduction in the Water Buffalo

“…Postpartum anoestrus is one of the major causes of the poor reproductive performances in buffaloes due to the lengthening of the calving interval (Zicarelli 1997b), although reproductive efficiency can possibly be improved in the immediate postpartum by, pharmacologically, speeding up the uterine involution (Ramoun et al. 2006).…”

“…Postpartum anoestrus is one of the major causes of the poor reproductive performances in buffaloes due to the lengthening of the calving interval (Zicarelli 1997b), although reproductive efficiency can possibly be improved in the immediate postpartum by, pharmacologically, speeding up the uterine involution (Ramoun et al 2006). In a recent study, Presicce et al (2005c) compared the ovarian function on primiparous and pluriparous postpartum buffaloes in a period of the year characterized by increasing daylight, when particularly sensitive buffaloes could more easily enter into seasonal anoestrus.…”