Effect of enhanced external counterpulsation on dobutamine-induced left ventricular wall motion abnormalities in severe chronic angina pectoris

Bagger, Jens Peder; Hall, Roger; Koutroulis, George; Nihoyannopoulos, Petros

doi:10.1016/j.amjcard.2003.10.045

Cited by 17 publications

(11 citation statements)

References 11 publications

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“…Compared with other patients, the 146 patients who did not complete their 3-year follow-up were younger (64.3 ± 11.7 versus 66.4 ± 10.7 years, p<0.05), their angina was more severe (CCSIII/IV 91.7% versus 88.8%, p<0.01) and frequent (10 [4-20] versus 6 [3][4][5][6][7][8][9][10][11][12][13][14] episodes/week, p<0.01), and history of HF was more prevalent (44.8% versus 33.8%, p<0.01). However, the workload they achieved on exercise stress test at baseline; their LVEF, the duration, distribution, and extent of their CAD; history of prior MI, previous revascularization, other cardiovascular risk factors, and medication use were similar to other patients.…”

Section: Baseline Patient Characteristicsmentioning

confidence: 95%

Enhanced External Counterpulsation in the Treatment of Chronic Refractory Angina: A Long‐term Follow‐up Outcome from the International Enhanced External Counterpulsation Patient Registry

Loh

Cleland

Louis

et al. 2008

Clinical Cardiology

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BackgroundThe management of patients who suffer from medically refractory angina and are unsuitable for conventional revascularization therapy is often unsatisfactory. Enhanced external counterpulsation (EECP) is a noninvasive treatment that is safe and effective immediately after a course of treatment. However, the duration of benefit is less certain.HypothesisTo evaluate the 3‐year outcome of EECP treatment.MethodsOne thousand four hundred and twenty seven patients from 36 centers registered in the International EECP Patient Registry (IEPR)—Phase 1 was prospectively followed for a median of 37 months. Two hundred and twenty patients (15.4%) died, while 1,061 patients (74.4%) completed their follow‐up.ResultsThe mean age was 66 ± 11 years and 72% were men. Seventy‐six percent had multivessel coronary disease for 11 ± 8 years. Eighty‐eight percent had a prior percutaneous or surgical revascularization and 82% were unsuitable for further coronary intervention.Immediately post‐EECP, the proportion of patients with severe angina (Canadian Cardiovascular Angina Classification [CCS] III/IV) were reduced from 89% to 25%, p<0.001. The CCS class was improved by at least 1 class in 78% of the patients and by at least 2 classes in 38%. This was sustained in 74% of the patients during follow‐up.Thirty‐six percent of the patients had CCS II or less angina, which was better than pre‐EECP state without a major adverse cardiovascular event during follow‐up. More severe baseline angina and a history of heart failure or diabetes were independent predictors of unfavorable outcome.ConclusionAn EECP improves angina and quality of life immediately after a course of treatment. For most of the patients, these beneficial effects are sustained for 3 years. Copyright © 2008 Wiley Periodicals, Inc.

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Section: Baseline Patient Characteristicsmentioning

confidence: 95%

Enhanced External Counterpulsation in the Treatment of Chronic Refractory Angina: A Long‐term Follow‐up Outcome from the International Enhanced External Counterpulsation Patient Registry

Loh

Cleland

Louis

et al. 2008

Clinical Cardiology

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“…Интересными явились результаты исследования Bagger J.P. и соавт., в котором по данным стресс-ЭхоКГ с добутамином (n=23) оценивалось влияние УНКП на локальную сократимость ЛЖ у пациентов со стабиль-ной стенокардией [34]. После УНКП индекс нарушения локальной сократимости левого желудочка (рассчи-тываемого по степени сократимости каждого из 17 сег-ментов) снизился у 43% пациентов, отмечалась нор-мализация или уменьшение нарушений локальной сократимости.…”

Section: Enhanced External Counterpulsation In Clinical Practiceunclassified

Possibilities of Enhanced External Counterpulsation Using in Clinical Practice

Mamieva

Лишута

Belenkov

et al. 2017

Racionalʹnaâ farmakoterapiâ v kardiologii

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Первый Московский государственный медицинский университет имени И.М. Сеченова Россия, 119991, Москва, ул. Трубецкая, 8 стр. 2 В статье рассматриваются возможности и перспективы применения в клинической практике такого метода лечения, как усиленная наружная контрпульсация (УНКП), уже давно зарекомендовавшего себя во всем мире. Рассматриваются исторические предпосылки, а также этапы раз-работки данного метода для лечения пациентов с ишемической болезнью сердца (ИБС) и хронической сердечной недостаточностью (ХСН). Детально разбирается механизм действия УНКП и основные гемодинамические, нейрогуморальные и тканевые эффекты, лежащие в осно-ве применения данного вида лечения. Отдельно рассматривается влияние УНКП на эндотелиальную функцию и коронарный резерв, нару-шение которых имеет место при большинстве сердечно-сосудистых заболеваний. Среди наиболее изученных показаний для применения УНКП является лечение пациентов с ИБС, в том числе, осложненной ХСН. В статье представлена доказательная база лечения больных этими на-рушениями с использованием УНКП. Также представлены перспективные направления применения этого метода лечения в других направ-лениях медицины.Ключевые слова: усиленная наружная контрпульсация, эндотелиальная функция, коронарный резерв, ишемическая болезнь сердца, хроническая сердечная недостаточность. Possibilities and prospects for the clinical use of enhanced external counterpulsation (EECP), which has long established itself throughout the world, are discussed in the article. Historical background, as well as the development stages of EECP for the treatment of patients with coronary heart disease (CHD) and chronic heart failure (CHF) are considered. The mechanism of action of the EECP and the main hemodynamic, neurohumoral and tissue effects that justify its use are presented. The effect of EECP on endothelial function and coronary reserve, disorders of which occurs in the majority of cardiovascular diseases, is considered separately. Treatment of patients with CHD, including complicated by CHF, are the most studied indications for EECP using in medical practice. The evidence base for treatment of patients with these disorders by EECP is presented in the article. Prospects for the EECP application in other areas of medicine are also presented.Keywords: enhanced external counterpulsation, endothelial function, coronary reserve, ischemic heart disease, chronic heart failure. ВведениеИшемическая болезнь сердца (ИБС) и сердечная не-достаточность по-прежнему сохраняют лидирующие по-зиции среди причин инвалидизации и смертности на-селения во всем мире. Несмотря на значительные до-стижения последних лет в диагностике и терапии дан-ных состояний, у определенной доли пациентов фар-макотерапия оказывается недостаточно эффективной, а использование эндоваскулярных и хирургических ме-тодов лечения не представляется возможным из-за осо-бенностей анатомии коронарного русла, предше-ствующей реваскуляризации или наличия тяжелых сопутствующих заболеваний. В этой ситуации воз-можно использование современных методов тера-

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“…In this prospective study, 43% of patients with severe chronic angina pectoris and had a positive dobutamine stress echocardiogram had normal or reduced dobutamine induced wall motion abnormalities after EECP therapy. (Bagger et al, 2004) British investigators assessed the immediate and long-term effect of EECP in treatment of chronic stable refractory angina. Sixty-one patients were treated with EECP and 58 completed a course of treatment.…”

Section: Eecp Therapy In Cad Managementmentioning

confidence: 99%

The Role of Enhanced External Counterpulsation Therapy in the Management of Coronary Artery Disease

Soran¹

2011

Angina Pectoris

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Effect of enhanced external counterpulsation on dobutamine-induced left ventricular wall motion abnormalities in severe chronic angina pectoris

Cited by 17 publications

References 11 publications

Enhanced External Counterpulsation in the Treatment of Chronic Refractory Angina: A Long‐term Follow‐up Outcome from the International Enhanced External Counterpulsation Patient Registry

Enhanced External Counterpulsation in the Treatment of Chronic Refractory Angina: A Long‐term Follow‐up Outcome from the International Enhanced External Counterpulsation Patient Registry

Possibilities of Enhanced External Counterpulsation Using in Clinical Practice

The Role of Enhanced External Counterpulsation Therapy in the Management of Coronary Artery Disease

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