Effect of Encapsulated Artemisia aucheri. L Magnetic Nanogel Extract on Shoulder Block in Rat

Beiranvand, Siavash; Karimi, Arash

doi:10.1055/s-0043-117180

Cited by 13 publications

(6 citation statements)

References 27 publications

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“…Previous history of the cause of back pain include; how the needles are inserted for spinal anesthesia, muscle strength presented, and risk factors for lower back pain [29]. Perhaps because women have less muscle mass, tendons becomes more flexible due to the presence of female sex hormones and lumbar lordosis, which accounts for more pain they are experiencing [30].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Complications between Gender during Spinal Anesthesia

Vahabi¹,

Karimi²,

Ghanavati³

2018

Journal of Surgery and Operative Care

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Background:The side effects of spinal anesthesia has been the focus of many researchers. These complications can affect patients' satisfaction following surgery and duration of hospitalization. Therefore, factors that lead to increased risk of side effects must be identified, one of these factors is gender. This study evaluated the relationship between gender and adverse effects after spinal anesthesia. Materials and Methods:In this cohort study, 1200 patients including 600 men and 600 women underwent spinal anesthesia with 5% lidocaine injected into L3-4 or L4-5interspace with the patient in either sitting or lateral position. The subjects include patients scheduled for lower abdominal site and orthopedic surgeries (leg to the bottom), analysis was done at 6, 12, 18, and 24 hours after recovery, and some variables in the second and third days were also analyed. To statistically analyze the side effects of spinal anesthesia, chi-square test was used.Result: Result showed that nausea, vomiting, headache, urinary retention (in recovery unit) and back pain (18hours) were statistically significantly different (P<0.05). There was no significant difference between the incidence of other complications and gender. Conclusion:According to this study, gender can lead to differences in the incidence of some complications after spinal anesthesia. Materials and MethodsThis study was carried out at Lorestan University of Medical Sciences (LUMS) teaching hospital, Khoramabad, Iran. In this cohort study, 1200 patients including 600 men and 600 women who went through spinal anesthesia were examined (Table 1). The subject are grouped into two, 600 were administered with 5% lidocaine which was injected into L3-4 or L4-5 interspace with the patient in either sitting or lateral position. The subjects include patients scheduled for lower abdominal site and orthopedic surgeries (leg to the bottom), analysis was done at 6, 12, 18, and 24 hours after recovery, and some variables in the second and third days were

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Section: Discussionmentioning

confidence: 99%

Comparison of Complications between Gender during Spinal Anesthesia

Vahabi¹,

Karimi²,

Ghanavati³

2018

Journal of Surgery and Operative Care

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“…Gibofsky and colleagues also in their study, assessed the palliative efficiency and tolerability of low drug dose of diclofenac loaded on submicron particle capsules and celecoxib compared to placebo in patients suffering from moderate pain after surgery and in addition, lower-dose diclofenac loaded on submicron particle significantly decreased the overall pain intensity, compared to placebo after elective surgery [41]. All these reported studies imply that diclofenac loaded on submicron particle capsules are possible potential alternative treatment for patients experiencing pain [42].…”

Section: Nano-diclofenac and Chronic Painmentioning

confidence: 98%

Nano-drug for Pain Medicine

Hasanzadeh-Kiabi

2017

Drug Res (Stuttg)

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Pain is commonly categorized into two diverse groups: acute pain, characterized by early onset and last for a very short time; while chronic pain, characterized by a prolonged pain for least 3 months' duration. Timely and immediate management of critical pain is critical in reducing its aggravation to chronic pain. There has been successful application of nano-technology, nano-medicine to the treatment and management of pain both in clinical and experimental studies like the fabrication of nano-formulated liposomes to deliver drugs for pain therapy, formulation of non- steroidal anti-inflammatory drugs (NSAIDs). However safety issues related with NSAIDs have impelled the fabrication and the design of new drug formulations that reduces side effects and sustain efficacy. This review will give a concise summary on the available studies on the application of nano-formulated drugs designed for pain treatment and management.

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“…A retrospective study by Butz et al, carried out on 90 patients with immediate implant-based breast reconstruction, showed that liposomal bupivacaine reduced patient visual analog pain scores in the immediate postoperative period, when compared with a bupivacaine pain pump and oral/ intravenous narcotic management of pain and decreased inpatient length of stay [56,57].…”

Section: Liposome Application In Pain Managementmentioning

confidence: 99%

Pain management using nanotechnology approaches

Beiranvand

Sorori

2019

Artificial Cells, Nanomedicine, and Biotechnology

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The proper treatment of pain is yet a major medical challenge. To obtain a long-term analgesia action, opioid therapy is the gold standard therapy for overcoming a chronic pain. Nanotechnology focus on formulating therapeutic agents encapsulated in a biocompatible nanocarriers (10-200 nanometer), these include but not limited to nanoparticles, liposomes and nanocapsules, micelles, dendrimers and nanotubes. This review gives an overview of current strategies of pain treatment with the help of the knowledge of nanotechnology. In addition, the applications of nano-innovation in oxidative therapy, genotoxicity and immunogenicity, are elucidated.

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Effect of Encapsulated Artemisia aucheri. L Magnetic Nanogel Extract on Shoulder Block in Rat

Cited by 13 publications

References 27 publications

Comparison of Complications between Gender during Spinal Anesthesia

Comparison of Complications between Gender during Spinal Anesthesia

Nano-drug for Pain Medicine

Pain management using nanotechnology approaches

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