Effect of Electrical Tooth Stimulation on Blood Flow, Interstitial Fluid Pressure and Substance P and CGRP-Immunoreactive Nerve Fibers in the Low Compliant Cat Dental Pulp

Heyeraas, Karin J.; Kim, Syngcuk; Raab, W.; Byers, Margaret R.; Liu, Mintsai

doi:10.1006/mvre.1994.1026

Cited by 68 publications

(55 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…14,25 However, in this study, a decrease in the PBF in the patients was detected, which is in agreement with the findings of Chen and Abbott. 17 Contrary to other conjunctive tissues, the inflammatory vascular reactions in the dental pulp take place in a rigid, enclosed dentin chamber.…”

Section: Discussionsupporting

confidence: 92%

In-office bleaching effects on the pulp flow and tooth sensitivity – case series

et al. 2015

View full text Add to dashboard Cite

Laser Doppler flowmetry (LDF) is a noninvasive method capable of evaluating variations in pulp blood flow (PBF) and pulp vitality. This method has thus far not been used to assess changes in blood flow after in-office bleaching. The aim of this case series report was to measure changes in PBF by LDF in the upper central incisor of three patients submitted to in-office bleaching. The buccal surfaces of the upper arch were bleached with a single session of 35% hydrogen peroxide gel with three 15-min applications. The color was recorded using a value-oriented Vita shade guide before in-office bleaching and one week after the procedure. The tooth sensitivity (TS) in a verbal scale was reported, and PBF was assessed by LDF before, immediately, and one week after the bleaching session. The lower arch was submitted to dental bleaching but not used for data assessment. A whitening degree of 3 to 4 shade guide units was detected. All participants experienced moderate to considerable TS after the procedure. The PBF readings reduced 20% to 40% immediately after bleaching. One week postbleaching, TS and PBF were shown to be equal to baseline values. A reversible decrease of PBF was detected immediately after bleaching, which recovered to the baseline values or showed a slight increase sooner than one week post-bleaching. The LDF method allows detection of pulp blood changes in teeth submitted to in-office bleaching, but further studies are still required.

show abstract

Section: Discussionsupporting

confidence: 92%

In-office bleaching effects on the pulp flow and tooth sensitivity – case series

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Our reason for determining interstitial compliance in this organ was the suggestion of a previous study that the salivary gland was a low-compliant organ and that this phenomenon could influence transcapillary fluid transport (4). In the control situation, we found a positive P if in the salivary gland, in agreement with previous data from the salivary gland (4) as well as other oral tissues (11,13,14). Finding an average compliance 36% of that found during corresponding changes in hydration in rat skin and muscle (20,28), we were able to verify our original hypothesis.…”

Section: I -P If Curve In Passive Alteration Of Salivary Gland Hydrsupporting

confidence: 92%

Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion

Berggreen¹,

Wiig²

2006

American Journal of Physiology-Heart and Circulatory Physiology

View full text Add to dashboard Cite

Berggreen, Ellen, and Helge Wiig. Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion. Am J Physiol Heart Circ Physiol 290: H1460 -H1468, 2006. First published November 11, 2005 doi:10.1152/ajpheart.00887.2005.-The submandibular gland transports fluid at a high rate through the interstitial space during salivation, but the exact level of all forces governing transcapillary fluid transport has not been established. In this study, our aim was to measure the relation between interstitial fluid volume (V i) and interstitial fluid pressure (Pif) in salivary glands during active secretion and after systemically induced passive changes in gland hydration. We tested whether interstitial fluid could be isolated by tissue centrifugation to enable measurement of interstitial fluid colloid osmotic pressure. During control conditions, V i averaged 0.23 ml/g wet wt (SD 0.014), with a corresponding mean P if measured with micropipettes of 3.0 mmHg (SD 1.3). After induction of secretion by pilocarpine, P if dropped by 3.8 mmHg (SD 1.5) whereas Vi was unchanged. During dehydration and overhydration of up to 20% increase of V i above control, a linear relation was found between volume and pressure, resulting in a compliance (⌬V i/⌬Pif) of 0.012 ml ⅐ g wet wt Ϫ1 ⅐ mmHg Ϫ1 . Interstitial fluid was isolated, and interstitial fluid colloid osmotic pressure averaged 10.4 mmHg (SD 1.2), which is 64% of the corresponding level in plasma. We conclude that P if drops during secretion and, thereby, increases the net transcapillary pressure gradient, a condition that favors fluid filtration and increases the amount of fluid available for secretion. The reduction in P if is most likely induced by contraction of myoepithelial cells and suggests an active and new role for these cells in salivary secretion. The relatively low interstitial compliance of the organ will enhance the effect of the myoepithelial cells on P if during reduced V i .interstitial fluid volume; micropuncture; pilocarpine IN SALIVARY GLANDS, blood, as well as salivary, flow is under autonomic nervous control, and transcapillary fluid transport and fluid flow through the interstitial space change dramatically after nervous stimuli before secretion of saliva from the epithelial cells. The high rate of fluid transport is reflected in the extremely high total capillary surface area in this organ, up to 500 cm 2 /g, which is among the highest in the body (6), and it has been estimated that the total fluid flux across the capillaries increases from a resting value of ϳ3 to 30 ml⅐min Ϫ1 ⅐100 g Ϫ1 during maximal parasympathetic stimulation (22). During salivation, gland volume, as well as interstitial fluid pressure (P if ), has been reported to decrease (15,22). The decrease in tissue volume was suggested to reflect expulsion of preformed saliva from the salivary ducts caused by contraction of the myoepithelial cells and/or reduction of cellular and/or interstitial fluid volume (V i ) in the initial phase of secretion after on...

show abstract

“…Dental pulp is known to have the highest concentration of SP outside of central nerve system 5) . Existence of SP like-immunoreactivity was confirmed in the dental pulp 6) .…”

mentioning

confidence: 79%

“…Therefore it is known to play an important part in vasoregulation: it is a strong vasodilator and increasing vascular permeability 6,8) and also involved in nociception (pain) associated with inflammation 9) . SP showed to exert flow response on the dental pulp 8) .…”

mentioning

confidence: 99%

See 1 more Smart Citation

Local application of NK1 receptor antagonists and pulpal blood flow in cat

Kim

Chu

Lee

et al. 2004

J Korean Acad Conserv Dent

View full text Add to dashboard Cite

Effect of Electrical Tooth Stimulation on Blood Flow, Interstitial Fluid Pressure and Substance P and CGRP-Immunoreactive Nerve Fibers in the Low Compliant Cat Dental Pulp

Cited by 68 publications

References 0 publications

In-office bleaching effects on the pulp flow and tooth sensitivity – case series

In-office bleaching effects on the pulp flow and tooth sensitivity – case series

Lowering of interstitial fluid pressure in rat submandibular gland: a novel mechanism in saliva secretion

Local application of NK1 receptor antagonists and pulpal blood flow in cat

Contact Info

Product

Resources

About