Effect of Effective Microorganisms (EM) in Blood Sugar Contrition and Some Biochemical Parameters in Normal and  Alloxan Induced  Diabetic Male Rats

Mohammed, Wadah J.; Sheet, Waleed; Rahim, Salh M.; Mohammed, Mousa J.

doi:10.33899/rjs.2011.31232

Cited by 8 publications

(4 citation statements)

References 2 publications

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“…The results of Table (4) showed a significant increase (P≤0.05) in the activity of the enzyme aminotransferase enzyme in the group of experimental diabetic rats (B), which reached 46.33 IU/l, compared with the intact control group (A), which was 21.67 IU/l, these results were consistent with what was mentioned by Mohammed et al, (2011) when they indicated a significant increase in the activity of the ALT enzyme compared to the intact control group. The cause of the increase in diabetic rats may be attributed to the damage to pancreatic beta cells caused by Alloxan (Ali et al, 2011).…”

Section: -5-2 Alanine Aminotranseferase (Alt) Activitysupporting

confidence: 90%

Study of the effect of Ethanolic extract of pomegranate peels on some blood serum biochemical parameters in alloxan induced diabetes male rats

Jandal

Naji

2021

TJAS

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This study was conducted in at the Biotechnology Research Center / Nahrain University / Baghdad Governorate, for the period 2/8/2020 to 15/9/2020, the follow of the effects of dosing with ethanolic extract of pomegranate peels on 30 male rats of (2-3) months of age and weights (170-220 g) were included, it was divided into two parts, one of which is intact and the other in which diabetes was introduced by using alloxan at a concentration (90 mg / kg) of body weight, The results showed of the biological study that the development of experimental diabetes showed significant increase (P <0.05) in the concentrations of Glucose, Total cholesterol (TC), Trigleserid (TG), low-density lipoproteins cholesterol (LDL-C), Very-low-density lipoprotein cholesterol (VLDL-C), and the enzymes of aspartate transaminase and alanine transaminase (AST و ALT), and malonedialdehyde concentration (MDA), Compared with a intact control group, while it led to a significant decrease (P <0.05) in body weight, insulin concentration, high-density lipoprotein cholesterol (HDL), in the affected control group. Dosing in intact rats with ethanolic extract of pomegranate peel at a concentration of 75 and 150 mg / kg of body weight led to a significant decrease in the concentrations of glucose, TC, TG, LDL-C and VLDL-C, as well as AST, ALT, and MDA enzymes, compared with a healthy control group, Significant increase in body weight, insulin and HDL-C concentrations for all treatments compared with the healthy control group. Dosing of diabetic rats with ethanolic extract of pomegranate peels at a concentration of 75 and 150 mg / kg of body weight led to a significant decrease in the concentrations of glucose, TC, TG, LDL-C and VLDL-C, as well as AST, ALT, and MDA enzymes, compared with the infected and untreated control group, a significant increase in body weight, insulin and HDL-C concentrations, for all treatments, compared with the affected control group.

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Section: -5-2 Alanine Aminotranseferase (Alt) Activitysupporting

confidence: 90%

Study of the effect of Ethanolic extract of pomegranate peels on some blood serum biochemical parameters in alloxan induced diabetes male rats

Jandal

Naji

2021

TJAS

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“…Five rats were isolated for control treatment (without infection), and the remaining rats were injected subcutaneously with Alloxan of Indian origin, which was prepared at the time of injection at a dose of 100 mg/kg of body weight. as it was dissolved by 1 gram of alloxan in 10 ml of physiological solution (normal saline) after starving the animals for 12 hours [19] and [20], decline after decline injection they were directly provided with food and the drinking water was replaced with a 5% glucose solution for a period of 24 hours to reduce the shock of the treatment decline [1]. After 72 hours, their blood sugar was checked using an Accu-Chek blood sugar test device of German origin to confirm that they had developed diabetes mellitus.…”

Section: Experiments Design 231 Induce Diabetes Mellitusmentioning

confidence: 99%

Effect of some Medical Plant Extracts and Chemicals on Hormones of Female Rats

Al-Ameen,

Al-Azzawi,

Fadhil

2023

IOP Conf. Ser.: Earth Environ. Sci.

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The study was carried out on 45 sexually mature female albino rats at the age of 7-8 weeks and weighing 160-180 ± 10 gm., nine treatments were used in this study, where five rats were isolated for control treatment (without infection). The remaining rats were injected (Subcutaneous) with Indian-made Alloxan, which was prepared at the time of injection at a dose of 100 mg/kg of body weight. The purpose of this study was to determine the effect of extracts of medical plants (Curcumin, Origanum majorana, and Vitex aguns-castus) at 50-100 mg/kg body weight and chemotherapy (metformin at 50 mg/kg body weight) on hormones. The results showed a significant increase in LH hormone in the T3, T4, T5, T7, and T9 treatments compared with the T2 treatment. A significant increase in FSH was observed in T3, T4, T5, T6, T7, and T9 treatments compared with T2 treatment. The results of the statistical analysis indicated a significant increase in progesterone in the T3, T5, T7, and T9 treatments compared with the T2 treatment. While T3, T5, and T9 treatments were significantly superior to T2, T4, T6, T7, and T8 treatments in terms of estrogen hormone. While a significant increase in cortisol was observed in the T2 treatment compared with the rest of the treatments. The aim of this study was to investigate the effect of aqueous extracts of Curcumin, Origanum majorana and Vitex aguns-castus leaves on the sex hormones of female rats. The results have shown that the aqueous extracts have a positive effect on hormones in female rats.

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“…The remaining rats were injected subcutaneously with Alloxan of Indian origin, which was prepared at the time of injection at a dose of 100 mg/kg of body weight. as it was dissolved by 1 gram of alloxan in 10 ml of physiological solution (normal saline) after starving the animals for 12 hours [19] and [20], decline after decline injection they were directly provided with food and the drinking water was replaced with a 5% glucose solution for a period of 24 hours to reduce the shock of the treatment decline [1]. After 72 hours, their blood sugar was checked using an Accu-Chek blood sugar test device of German origin to confirm that they had developed diabetes mellitus.…”

Section: Experiments Design Induce Diabetes Mellitusmentioning

confidence: 99%

Effect of Some Medicinal Plants Extracts and Chemicals on Enzymes and Tissues Liver of Female Rats

Khaleel

2023

kujas

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The study was carried out on 45 sexually mature female albino rats at the age of 7-8 weeks and weighing 160-180; nine treatments were used in this study, where five rats were isolated for the control treatment (without infection); the remaining rats were injected (Subcutaneous) with Indian-made Alloxan, which was prepared at the time of injection at a dose of 100 mg/kg of body weight. The results showed a significant decrease in liver enzymes AST and the ALP characteristic in T3, T4, T5, T6, T7, T8, and T9, as well as a significant decrease in the ALT characteristic in T3, T5, T6, T7, and T9. Histological effects We notice severe damage to the liver tissue of alloxan-treated rats compared to the proper treatment, represented in the liver tissue by necrosis of liver cells, the presence of a blood clot, the absence of sinusoids, and the thickening of the nuclei. The results have shown that the aqueous extracts positively affect zymes and tissues in female rats.

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Effect of Effective Microorganisms (EM) in Blood Sugar Contrition and Some Biochemical Parameters in Normal and Alloxan Induced Diabetic Male Rats

Cited by 8 publications

References 2 publications

Study of the effect of Ethanolic extract of pomegranate peels on some blood serum biochemical parameters in alloxan induced diabetes male rats

Study of the effect of Ethanolic extract of pomegranate peels on some blood serum biochemical parameters in alloxan induced diabetes male rats

Effect of some Medical Plant Extracts and Chemicals on Hormones of Female Rats

Effect of Some Medicinal Plants Extracts and Chemicals on Enzymes and Tissues Liver of Female Rats

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