Effect of early hypoglycaemia on hospitalization outcomes in patients undergoing coronary artery bypass grafting

Li, Xiaojue; Hou, Xiaopei; Zhang, Heng; Qian, Xiaoxian; Feng, Xinxing; Shi, Na; Sun, Hansong; Feng, Wei; Zhao, Wei; Li, Guangwei; Zheng, Zhe; Chen, Yanyan

doi:10.1016/j.diabres.2022.109830

Cited by 4 publications

(5 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Third, it is necessary to reasonably control the patients’ blood glucose levels after the operation. Low blood glucose levels were found to be correlated with poor cardiovascular prognosis of CAD patients [ 23 , 24 ]. Following cardiac surgery, appropriate blood glucose level control (7.8–10.0 mmol/L) could help improve clinical outcomes [ 25 , 26 ].…”

Section: Discussionmentioning

confidence: 99%

The efficacy of minimally invasive coronary artery bypass grafting (mics cabg) for patients with coronary artery diseases and diabetes: a single center retrospective study

Guangxin,

Liqun,

Lin

et al. 2024

J Cardiothorac Surg

View full text Add to dashboard Cite

Background conventional coronary artery bypass grafting (CCABG) tends to cause severe complications in patients with comorbid Coronary Artery Diseases (CAD) and diabetes. On the other hand, the Minimally Invasive Cardiac Surgery Coronary Artery Bypass Grafting (MICS CABG) via transthoracic incision is associated with rapid recovery and reduced complications. Adding to the limited literature, this study compares CCABG and MICS CABG in terms of efficacy and safety. Methods Herein, 104 CCABG and MICS CABG cases (52 cases each) were included. The patients were recruited from the Minimally Invasive Cardiac Surgery Center, Anzhen Hospital, between January 2017 and December 2021 and were selected based on the Propensity Score Matching (PSM) model. The key outcomes included All-cause Death, Myocardial Infarction (MI), Cerebrovascular Events, revascularization, Adverse Wound Healing Events and one-year patency of the graft by coronary CTA. Results Compared to CCABG, MICS CABG had longer surgical durations [4.25 (1.50) h vs.4.00 (1.13) h, P = 0.028], but showed a reduced intraoperative blood loss [600.00 (400.00) mL vs.700.00 (300.00) mL, P = 0.032] and a lower secondary incision debridement and suturing rate (5.8% vs.19.2%, P = 0.038). In follow up, no statistically significant differences were found between the two groups in the cumulative Major Adverse Cardiovascular and Cerebrovascular Events (MACCEs) incidence (7.7% vs. 5.9%), all-cause mortality (0 vs. 0), MI incidence (1.9% vs. 2.0%), cerebral apoplexy incidence (5.8% vs. 3.9%), and repeated revascularization incidence (0 vs. 0) (P > 0.05). Additionally, coronary CTA results revealed that the two groups’ one-year graft patency (94.2% vs. 90.2%, P = 0.761) showed no statistically significant difference. Conclusion In patients with comorbid CAD and diabetes, MICS CABG and CCABG had comparable revascularization performances. Moreover, MICS CABG can effectively reduce, if not prevent, poor clinical outcomes/complications, including incision healing, sternal infection and prolonged length of stay in diabetes patients.

show abstract

Section: Discussionmentioning

confidence: 99%

The efficacy of minimally invasive coronary artery bypass grafting (mics cabg) for patients with coronary artery diseases and diabetes: a single center retrospective study

Guangxin,

Liqun,

Lin

et al. 2024

J Cardiothorac Surg

View full text Add to dashboard Cite

show abstract

“…For cardiac surgery patients, several studies and randomized controlled trials have revealed that decreasing the patient's glucose level could reduce the risk of short‐ and long‐term adverse outcomes and hospital death 12,26 . Continuous intravenous insulin infusions are recommended in clinical guidelines for patients with and without diabetes, those who are critically ill, or those undergoing cardiac surgery 27,28,29 . Our previous study 19 showed that better glucose control (<7.8 mmol/L) could reduce the risk of postoperative complications in patients without diabetes.…”

Section: Discussionmentioning

confidence: 99%

“…12,26 Continuous intravenous insulin infusions are recommended in clinical guidelines for patients with and without diabetes, those who are critically ill, or those undergoing cardiac surgery. 27,28,29 Our previous study 19 showed that better glucose control (<7.8 mmol/L) could reduce the risk of postoperative complications in patients without diabetes. In this study, we also analysed the risk factors for SH after CABG.…”

Section: Risk Factors For Stress Hyperglycaemiamentioning

confidence: 99%

Association between stress hyperglycaemia and in‐hospital cardiac events after coronary artery bypass grafting in patients without diabetes: A retrospective observational study of 5450 patients

Hou

Zhang

et al. 2023

Diabetes Obesity Metabolism

Self Cite

View full text Add to dashboard Cite

Aims: To investigate the impact of stress hyperglycaemia (SH) on in-hospital adverse cardiac events after coronary artery bypass grafting (CABG) in patients without diabetes.Materials and Methods: In total, 5450 patients without diabetes who underwent CABG were analysed. SH was defined as any two instances in which the random blood glucose level was >7.8 mmol/L after CABG in the intensive care unit (ICU). The primary outcome was major adverse cardiac events (MACEs), including in-hospital mortality, acute myocardial infarction, stroke and acute renal failure. Secondary outcomes included surgical site infection (SSI) and length of ICU stay.Results: Patients with SH had higher rates of MACEs (5.7% vs. 2.3%, p < .0001) and higher SSI (3.3% vs. 1.4%, p = .0003) and longer ICU stays (2.6 ± 2.0 vs. 1.3 ± 1.3 days, p < .0001) than those without SH. Furthermore, SH was associated with a higher risk of MACEs [odds ratio (OR): 2.32, 95% confidence interval (CI): 1.38-3.90],

show abstract

“…Furthermore, it is necessary to reasonably control the patients' blood glucose levels after the operation. Low blood glucose levels were found to be correlated with poor cardiovascular prognosis of CAD patients [21,22] . Following cardiac surgery, appropriate blood glucose level control (7.8-10.0 mmol/L) could help improve clinical outcomes [23,24] .…”

Section: Incomplete Vascularization and Graft Lesions Are Common Caus...mentioning

confidence: 93%

The Efficacy of Minimally Invasive Coronary Artery Bypass Grafting (MICS CABG) for Patients with Coronary Artery Diseases and Diabetes: A Single Center Retrospective Study

ZHAO,

CHI,

LIANG

et al. 2023

Preprint

View full text Add to dashboard Cite

Background conventional coronary artery bypass grafting (CCABG) tends to cause severe complications in patients with comorbid Coronary Artery Diseases (CAD) and diabetes. On the other hand, the Minimally Invasive Cardiac Surgery Coronary Artery Bypass Grafting (MICS CABG) via transthoracic incision is associated with rapid recovery and reduced complications. Adding to the limited literature, this study compares CCABG and MICS CABG in terms of efficacy and safety.Methods Herein, 104 CCABG and MICS CABG cases (52 cases each) were included. The patients were recruited from the Minimally Invasive Cardiac Surgery Center, Anzhen Hospital, between January 2017 and December 2021 and were selected based on the Propensity Score Matching (PSM) model. The key outcomes included All-cause Death, Myocardial Infarction (MI), Cerebrovascular Events, revascularization, Adverse Wound Healing Events and one-year patency of the graft by coronary CTA.Results Compared to CCABG, MICS CABG had longer surgical durations[4.25 (1.50) h vs.4.00 (1.13) h, p = 0.028], but showed a reduced intraoperative blood loss [600.00 (400.00) mL vs.700.00 (300.00) mL, p = 0.032] and a lower secondary incision debridement and suturing rate (5.8% vs.19.2%, p = 0.038). No statistically significant differences were found between the two groups in the cumulative Major Adverse Cardiovascular and Cerebrovascular Events (MACCEs) incidence (7.7% vs. 5.9%), all-cause mortality (0 vs. 0), MI incidence (1.9% vs. 2.0%), cerebral apoplexy incidence (5.8% vs. 3.9%), and repeated revascularization incidence (0 vs. 0) (p > 0.05). Additionally, coronary CTA results revealed that the two groups’ one-year graft patency (94.2% vs. 90.2%, p = 0.761) showed no statistically significant difference.Conclusion In patients with comorbid CAD and diabetes, MICS CABG and CCABG had comparable revascularization performances. Moreover, MICS CABG can effectively reduce, if not prevent, poor clinical outcomes/complications, including incision healing, sternal infection, prolonged length of stay, and slow recovery of body function in diabetes patients.

show abstract

Effect of early hypoglycaemia on hospitalization outcomes in patients undergoing coronary artery bypass grafting

Cited by 4 publications

References 26 publications

The efficacy of minimally invasive coronary artery bypass grafting (mics cabg) for patients with coronary artery diseases and diabetes: a single center retrospective study

The efficacy of minimally invasive coronary artery bypass grafting (mics cabg) for patients with coronary artery diseases and diabetes: a single center retrospective study

Association between stress hyperglycaemia and in‐hospital cardiac events after coronary artery bypass grafting in patients without diabetes: A retrospective observational study of 5450 patients

The Efficacy of Minimally Invasive Coronary Artery Bypass Grafting (MICS CABG) for Patients with Coronary Artery Diseases and Diabetes: A Single Center Retrospective Study

Contact Info

Product

Resources

About