Effect of drying method on the anticancer activity and metabolite profile of Mango (Mangifera indica) leaf extracts as revealed using LC‐MS/MS metabolomics
Cesar Quizon,
Michael Russelle Alvarez,
Patrick Moreno
et al.
Abstract:Mangifera indica is a widely‐distributed crop with known pharmacological properties. Knowing that sample preparation techniques could affect the chemical composition of natural products, we studied the effect of three common sample preparation methods ‐ airdrying, oven‐drying, and grinding in liquid‐nitrogen– on the compositions and bioactivities of n‐hexane, ethyl‐acetate, and methanol extracts of M. indica. By leveraging the Feature‐Based Molecular Networking (FBMN) of GNPS coupled with feature‐detection of … Show more
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