Effect of Disease and Stress Resistance Associated Genotypes on Productivity in Pigs

Abstract

Porcine infectious diseases are still causing great damage to the pig industry. Various molecular genetic analyses on improving stress or disease resistance have been continuously conducted to solve these obstacles. GBP5 SNPs and RYR1 SNPs are known to be casual mutations related to resistance to porcine reproductive respiratory syndrome virus(PRRSV) infection and porcine stress syndrome (PSS), respectively. The objective of this study was to validate the effect of the two SNP genotypes on basic economic traits related to productivity, including lean meat production capacity and meat quality in Landrace pigs. The pigs were genotyped by the PCR-RFLP method, and the unfavorable allele was not shown in the RYR1 SNP locus. Regarding GBP5 SNP locus, the frequency of the GT genotype, consisting of T allele resistant to PRRSV infection, was 0.13. In the association analysis of GBP5 genotypes, there was no significant association between the productivity related traits(p<0.05). The results implicated that the GBP5 genotypes could be integrated to the typical breeding program without loss in their productivity.