Digital health includes a variety of modern methods that may support smoking cessation. In light of increasing interest in digital health interventions and the widespread digitizaton of the digitalization process in Europe, it seems relevant to assess its efficacy. This review aims to present the current knowledge regarding using digital interventions for tobacco cessation in different population groups. The PubMed and Google Scholar databases were searched for systematic reviews and meta-analyses regarding digital health interventions in smoking cessation. It was found that a wide range of methods have been studied for supporting smoking cessation. Digital interventions offer encouraging tools for the general population in health education but also for smokers and specific groups of patients in smoking cessation. Despite the promising results of some individual studies, most of the systematic reviews emphasized the need for further research and better-quality data to assess the efficacy of this approach.