Effect of dietary α-tocopheryl acetate and ascorbic acid on rabbit semen stored at 5 °C

Castellini, Cesare; Lattaioli, P.; Bernardini, M.; Bosco, Alessandro Dal

doi:10.1016/s0093-691x(00)00367-8

Cited by 37 publications

(22 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In addition to the improvements in blood plasma biochemical indices, Vit C or Vit E with Se or probiotic supplementation also overcame the negative effect of 700 ppm of nitrate on seminal plasma total protein, albumin, urea, creatinine, testosterone, AST and ALT activity. These results are in agreement with the works of Castellini et al (2000 and. The protective effect of Vit E against the adverse effect of nitrate/nitrite could be attributed to its ability to reduce peroxynitrite (ONOO-) formation, whereas Se exerts its protective influences through seleno-enzymes/compounds, which reduce ONOO-formed (Chow and Hong, 2002).…”

Section: Discussionsupporting

confidence: 91%

“…These novel findings indicated that Vit C and Vit E with Se as an antioxidant or probiotic as gut function enhancer eliminated the negative effect of nitrate on most of the semen quality and reproductive traits (fertility, number of offspring and total offspring weight), and this concurred with increasing plasma TAC, which indicated an increase in body antioxidant reserve and/or a decrease in oxidative stress. The positive effect of these agents included an increase in Hgb, blood plasma globulin, RBCs and PCV% and increasing testosterone (Castellini et al, 2000;El-Kelawy, 2003). In addition, Brun et al (2002) found that the mass motility (number of motile sperm per ejaculate) significantly influenced the conception rate and this agree with the increase in advanced motility observed of bucks supplemented with Vit C, E with Se and probiotic.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The detoxication of nitrate by two antioxidants or a probiotic, and the effects on blood and seminal plasma profiles and reproductive function of New Zealand White rabbit bucks

Attia

Hamid

Ismaiel

et al. 2013

Animal

View full text Add to dashboard Cite

Forty-two New Zealand White male rabbits were housed individually in wire cages and randomly distributed among six experimental groups of seven rabbits each, during 16 to 61 weeks of age. There were three main nitrate groups: 0 (tap water), 350 and 700 ppm. Within the 700 ppm of nitrate, there were four subgroups, in which one group was used as control group and the other three groups were supplemented with either 200 ppm of ascorbic acid (vitamin (Vit) C), 200 ppm of Vit E with 0.2 ppm of selenium (Se) and 1000 ppm of probiotic. The nitrate was supplemented as a sodium nitrate. The aim is to test the ability of Vit C and Vit E, Se and probiotic on the deleterious effects (blood and seminal plasma biochemical constituents, semen quality and productive performance) of nitrate in drinking water. Rabbits given nitrate at 700 ppm had significantly lower plasma globulin, red blood cells (RBCs), hemoglobin (Hgb), packed cell volume % (PCV%) and total antioxidant capacity (TAC) than those given the other concentrations of nitrate. Vit C, Vit E with Se and probiotic resulted in significantly (P , 0.05) greater Hgb, RBCs, PCV% and TAC than those of bucks given water supplemented with only 700 ppm nitrate, but the aspartate aminotransferase and alanine aminotransferase concentrations in seminal plasma were lower. Testosterone in the blood plasma and the seminal plasma was significantly (P , 0.05) lower in rabbits given 700 ppm nitrate than in those given other concentrations of nitrate. Vit C, Vit E with Se and the probiotic significantly increased testosterone, fertility, number of offspring and total offspring weight of rabbits sired by bucks supplemented with 700 ppm of nitrate.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 99%

The detoxication of nitrate by two antioxidants or a probiotic, and the effects on blood and seminal plasma profiles and reproductive function of New Zealand White rabbit bucks

Attia

Hamid

Ismaiel

et al. 2013

Animal

View full text Add to dashboard Cite

show abstract

“…Hence, their combination significantly improves the viability and kinetics of spermatozoa with an increased fertility rate [89]. These evidences sustain the role of the co-administration of vitamins E and C for the improvement of sperm quality in idiopathic male infertility.…”

Section: Combined Therapiessupporting

confidence: 52%

Role of Antioxidants in the Treatment of Male Infertility

Gadallah¹

2018

SMOAJ

View full text Add to dashboard Cite

“…Although the protective action can be better obtained by avoiding megadoses of antioxidants [37] and by the administration of physiological amounts, the optimum level of some key vitamins required for maintaining the health or enhancing some specific functions is higher than that needed for the prevention of deficiency [38]. 0.5 g·L -1 of ascorbate and amounts of vitamin E 4-fold higher than the requirement [30] did not show any negative response on the antioxidant capacity of the organism.…”

Section: Discussionmentioning

confidence: 99%

“…On the contrary, vitamin C, largely present in the aqueous phase of the rabbit seminal plasma (about 180-250 µmol·L -1 [37]), reduced ROMs and lipoperoxides, neutralising oxidants before they began to attack the fatty acids of spermatozoa.…”

Section: Discussionmentioning

confidence: 99%

Oxidative status and semen characteristics of rabbit buck as affected by dietary

Castellini¹,

Lattaioli²,

Bosco³

et al. 2003

Reprod. Nutr. Dev.

View full text Add to dashboard Cite

International audienceThe aim of this study was to investigate the effect of dietary supplementation of long chain fatty acids (C $\geq$ 20 LCP) of the n-3 series, vitamin E and vitamin C on the antioxidant capacity of rabbit buck and on semen characteristics. Fifty male rabbits at 30 days were randomly assigned to five different diets: Control (50 mg$\cdot$kg$^{-1}$ diet $\alpha$-tocopheryl acetate), Vitamin E (200 mg$\cdot$kg$^{-1}$ diet $\alpha$-tocopheryl acetate), n-3 (2% ROPUFA oil + 50 mg$\cdot$kg$^{-1}$ diet $\alpha$-tocopheryl acetate), n-3 + E (2% ROPUFA oil + 200 mg$\cdot$kg$^{-1}$ diet $\alpha$-tocopheryl acetate) and n-3 + E C (2% ROPUFA oil + 200 mg$\cdot$kg$^{-1}$ diet $\alpha$-tocopheryl acetate + 0.5 g$\cdot$L$^{-1}$ vitamin C in the drinking water). The levels of vitamins E and C and reactive oxygen metabolites (ROMs) in the blood plasma were evaluated at different ages. The antioxidant capacity and ROMs of seminal plasma, the fatty acid profile of sperm phospholipids, the semen traits and the oxidative processes during storage (24 h at + 4 °C) were carried out weekly for 5 wk starting from the 5th month of age. Vitamin E addition showed enough antioxidant protection only when associated with no lipid enriched diets. The n-3 supplementation modified the fatty acid profile of the spermatozoa membrane and simultaneously enhanced oxidative processes. Only the association with supranutritional levels of vitamins E and C inhibited the oxidative processes and improved the characteristics of fresh and stored rabbit semen

show abstract

Effect of dietary α-tocopheryl acetate and ascorbic acid on rabbit semen stored at 5 °C

Cited by 37 publications

References 20 publications

The detoxication of nitrate by two antioxidants or a probiotic, and the effects on blood and seminal plasma profiles and reproductive function of New Zealand White rabbit bucks

The detoxication of nitrate by two antioxidants or a probiotic, and the effects on blood and seminal plasma profiles and reproductive function of New Zealand White rabbit bucks

Role of Antioxidants in the Treatment of Male Infertility

Oxidative status and semen characteristics of rabbit buck as affected by dietary

Contact Info

Product

Resources

About