Effect of Dietary Supplementation of Organic Acids on Performance, Intestinal Histomorphology, and Serum Biochemistry of Broiler Chicken

Abstract

The aim of the study was to determine the effect of dietary supplementation of organic acids on the performance, intestinal histomorphology, and blood biochemistry of broiler chicken. The birds in the control (T1) group were fed the basal diet whereas in other treatment groups basal diet was supplemented with 2% butyric acid (T2), 3% butyric acid (T4), 2% fumaric acid (T4), 3% fumaric acid (T5), 2% lactic acid (T6), and 3% lactic acid (T7). Broiler chicken fed diets supplemented with organic acids had significantly (P < .05) improved body weight gains and feed conversion ratio. No effect (P < .05) on cumulative feed consumption was observed. The addition of organic increased villus height in the small intestines but the differences were not significant (P < .05) in case of the ileum. Serum calcium and phosphorus concentrations were increased (P < .05) but no effect (P < .05) on the concentration of serum glucose and cholesterol, serum glutamic pyruvic transaminase (SGPT), and serum glutamic oxaloacetate transaminase (SGOT) was observed. The results indicated that the organic acid supplementation, irrespective of type and level of acid used, had a beneficial effect on the performance of broiler chicken.

Sodium butyrate in chicken nutrition: the dynamics of performance, gut microbiota, gut morphology, and immunity

“…Significantly higher duodenal villi density was reported in response to 3% sodium butyrate in comparison with 2% sodium butyrate (Adil et al, 2011). Adil et al (2010) reported that dietary butyric acid (3% application rate) significantly increased the villus height in the duodenum and jejunum only. Similarly, many researchers have described the beneficial effect of dietary sodium butyrate on villi height and crypt depth in broilers at different phases of their growth (Antongiovanni et al, 2007;Mallo et al, 2012;Panda et al, 2009;Sayrafi et al, 2011;Smulikowska et al, 2009).…”

Butyric Acid as an Antibiotic Substitute for Broiler Chicken A Review

“…Further, an increase in the villus height and villus height to crypt depth ratio are directly correlated with increased epithelial cell turnover (Fan et al, 1997) and an indicator of activated intestinal villi function (Langhout et al, 1999;Shamoto and Yamauchi, 2000) and it also stimulates intestinal blood flow. In addition, butyrate of stimulates cell growth and differentiation of normal cells and apoptosis (early cell death) of tumour cells which represents'butyrate paradox' (Canani et al, 2011).Previous studies showed increased jejunum villi height (Adil et al, 2010;Jerzsele et al, 2012;Chamba et al, 2014), villi height to crypt depth ratio (Hu and Guo, 2007;Shahir et al, 2013) and comparable crypt depth (Hu and Guo, 2007;Adil et al, 2010;Smulikowska et al, 2009;Chamba et al, 2014;Sayrafi et al, 2011;Antongiovanni et al, 2007) by supplementation of different forms of butyric acid. Lakshmi and Sunder (2015) 0.25 Liver weight + Aghazadeh and Yazdi (2012) It is clear from the Table 4 that inclusion of BA in broiler diet improves the weight of carcass indicating anabolic effect in broiler chicken.…”

“…Earlier works with BAG supplemented at 0.3 (Mahdavi and Torki, 2009) and BA at 3.0 % (Adil et al, 2010;Kamal and Ragaa, 2014) in broiler ration increased serum calcium level. The latter authors also documented increased serum phosphorus (Adil et al, 2010;Kamal and Ragaa, 2014) and magnesium levels (Kamal and Ragaa, 2014).…”

“…BA supplementation at 3.0 % (Kamal and Ragaa, 2014;Adil et al, 2010) did not influence the serum Alanine Transaminase (ALT) and Aspartate Transaminase (AST) levels in broilers. In Eimeria maxima challenged-birds, inclusion of BAG at 0.4 % prevented the elevation of serum ALT and AST levels as found in positive control indicating that butyric acid, at times, have the protective effect over hepatocytes (Ali et al, 2014).…”

Effects of Acidified Yeast and Whey Powder on Performance, Organ Weights, Intestinal Microflora, and Gut Morphology of Male Broilers

“…It has been shown that yeast product contains beneficial nutrients such as peptides, oligosaccharides, flavors and aroma substances which increase nutrient digestibility, enhance the growth of beneficial bacteria such as Lactobacillus and improve gut immunity against pathogens (Roto et al, 2015). Adil et al (2010) supplemented broiler diets with various levels of different organic acids to evaluate the effects of acidifiers on productive performance and gut morphology. They concluded that acidifiers enhanced growth performance and gut health and morphology in broilers, irrespective of the type and levels of organic acids.…”