Effect of dietary supplementation of chitosan and galacto-mannan-oligosaccharide on serum parameters and the insulin-like growth factor-I mRNA expression in early-weaned piglets

Tang, Zhi Ru; Yu, Yancun; Nyachoti, C. M.; Huang, Rui; Li, Tie Jun; Yang, Chengbo; Yang, Xiangwei; Gong, Joshua; Peng, Jiang; Qi, Desheng; Xing, Jian Jun; Sun, Zhihong; Fan, Ming Z.

doi:10.1016/j.domaniend.2005.02.003

Cited by 136 publications

(97 citation statements)

References 11 publications

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“…Our findings agree with the results of earlier studies in which chitosan (used as a prebiotic supplement) was found to lower the concentration of blood lipids of broiler chicks (Tang et al, 2005;Li et al, 2007). Also, Kannan et al (2005) reported that MOS fed broilers had statistically reduced serum triglycerides concentration than the control broiler at 5 weeks of age.…”

Section: Serum Biochemical Metabolites and Hematological Parameterssupporting

confidence: 93%

Evaluation of Oyster Mushroom (<i>Pleurotus Ostreatus</i>) as a Biological Growth Promoter on Performance, Humoral Immunity, and Blood Characteristics of Broiler Chicks

et al. 2012

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This study was conducted to determine the impacts of two levels of oyster mushroom (Pleurotus ostreatus) powder on productive and carcass traits, humoral immune responses, and blood characteristics of Ross 308 male broiler chicks reared to 42 d of age in comparison with a prebiotic supplement. Two hundred and forty, day-old male broiler chicks (Ross 308) were randomly assigned to one of four treatments with four replicates of 15 chicks based on a completely randomized design. The dietary treatments consisted of the basal diet as control, prebiotic group receiving 1 g/kg A-Max ® (Mannan-oligosaccharides), 10, and 20 g/kg oyster mushroom powder added to the basal diet. The obtained results showed that inclusion of 20 g/kg mushroom powder significantly improved body weight over the starter and grower (P＜0.05) while feed efficiency was improved only over the starter (P＜0.05) period compared to the control group. Considering the entire experimental period, (1-42 d) birds receiving prebiotic supplemented diets exhibited the highest body weight and lowest feed conversion ratio relative to the other treatments (P＜0.05). Carcass yield and internal organs relative weights were not influenced by dietary treatments, but prebiotic supplementation significantly (P＜0.05) decreased abdominal fat pad compared to the control group. Newcastle, influenza and sheep red blood cell antibody responses of chicks did not differ significantly at either level of inclusion of supplements. Chicks fed supplemented diets had the lowest serum triglyceride concentration at 42 day (P＜0.05) compared to the control chicks, but other biochemical and hematological values tested including protein, albumin, globulin, high-density lipoprotein, low-density lipoprotein, and total cholesterol, red blood cell, white blood cell, hemoglobin and hematocrit were not markedly affected by treatments. In conclusion the obtained results indicated that oyster mushroom powder at an inclusion level of 20 g/kg of diet had favorable effects on performance criteria of chicks reared to 28 day of age while, prebiotic supplementation revealed its beneficial impact on chicks productive traits at slaughter age, besides reducing carcass abdominal fat and serum triglyceride concentration at 42 day.

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Section: Serum Biochemical Metabolites and Hematological Parameterssupporting

confidence: 93%

Evaluation of Oyster Mushroom (<i>Pleurotus Ostreatus</i>) as a Biological Growth Promoter on Performance, Humoral Immunity, and Blood Characteristics of Broiler Chicks

et al. 2012

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“…minerals) and improve meat quality by altering lipid metabolism in livestock and poultry. 12,16,23 The mechanisms whereby dietary supplementation with prebiotcs improved nutrient utilisation in animals are likely multifactorial. One of the complex mechanism has been suggested to involve an increase in the amount of those beneficial bacteria (e.g.…”

Section: Discussionmentioning

confidence: 99%

“…5,8 Specifically, IL-6 may reduce the number of pathogenic bacteria (e.g. Escherichia coli, Salmonella trphimurium and Streptococci) 12,27,28 and increase the number of beneficial bacteria (e.g. Lactobacilli) 29 in the gastrointestinal tract.…”

Section: Discussionmentioning

confidence: 99%

“…Chitosan has been shown to alter avian lipid metabolism by decreasing blood levels of triglycerides and total cholesterol and improving performance and meat quality. 11,12 Wang et al 8 reported that dietary supplementation with 0.1% of chitosan reduced the number of E. coli in the GIT of chicks, while improving the small intestinal microvilli density, 8 serum antibody titre against the Newcastle disease virus, and growth performance. 8 Additionally, results of the studies on humans and mice indicated that chitosan inhibited oral streptococci, 13 reduced early preneoplastic markers of colon carcinogenesis, 14 and stimulated mucosal and systemic antibody responses against Bordetella pertussis filamentous haemagglutinin and recombinant pertussis.…”

Section: Introductionmentioning

confidence: 99%

“…16 We have also reported that dietary supplementation of COS to weanling piglets promoted intestinal microflora balance and enhanced immune function. 12 At present, little is known about the effect of chitosan on the development of avian lymphoid organs or the molecular mechanisms of its action on the immune response. The objective of this study was to determine the effects of dietary supplementation with chitosan on immune functions in growing broilers.…”

Section: Introductionmentioning

confidence: 99%

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