Effect of dietary polyphenols on cardiovascular risk

Lamuela‐Raventós, Rosa M.; Quifer-Rada, Paola

doi:10.1136/heartjnl-2016-309647

Cited by 5 publications

(9 citation statements)

References 6 publications

(6 reference statements)

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“…Currently, the major risk factor for developing cardio- and cerebrovascular diseases is hypertension, and it is the major global health problem, affecting approximately 1 billion individuals and causing 7.6 million premature deaths, as well as 6% of all causes of disability worldwide [ 16 ]. Antihypertensives were the most distributed drugs (698 million prescriptions) in the US during 2013 [ 12 ].…”

Section: Dietary Polyphenols and Cvdmentioning

confidence: 99%

“…Studies with tea and cocoa found an improvement in indirect measures of sympathetic nervous system activity patterns, possibly contributing to the lowering of peripheral vascular tone [ 27 ]. Moreover, hydroxytyrosol, oleuropein, and secoiridoids, found mainly in olives or virgin olive oils, may protect LDL particles from oxidation [ 12 ]. Further, cocoa flavanols have been assessed to play a role in maintaining endothelium-dependent vasodilation [ 12 ].…”

Section: Dietary Polyphenols and Cvdmentioning

confidence: 99%

“…Moreover, hydroxytyrosol, oleuropein, and secoiridoids, found mainly in olives or virgin olive oils, may protect LDL particles from oxidation [ 12 ]. Further, cocoa flavanols have been assessed to play a role in maintaining endothelium-dependent vasodilation [ 12 ].…”

Section: Dietary Polyphenols and Cvdmentioning

confidence: 99%

“…Moreover, herbs, spices, and nuts are also potentially relevant polyphenol sources [ 10 , 11 ]. The current dietary advice is that people should consume ≥5 portions of fruit and vegetables every day, each portion being at least 80 grams (U.S. Department of Health and Human Services, 2010), keep the body mass index from 18.5 to 24.9 kg/m 2 , and perform physical exercise [ 12 ].…”

Section: Introductionmentioning

confidence: 99%

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Dietary Polyphenols in the Prevention of Stroke

Tressera-Rimbau

Arranz

Eder

et al. 2017

Oxidative Medicine and Cellular Longevity

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Polyphenols have an important protective role against a number of diseases, such as atherosclerosis, brain dysfunction, stroke, cardiovascular diseases, and cancer. Cardiovascular diseases are the number one cause of death worldwide: more people die annually from cardiovascular diseases than from any other cause. The most important behavioural risk factors of heart disease and stroke are unhealthy diet, physical inactivity, tobacco use, and excess alcohol intake. The dietary consumption of polyphenols has shown to be inversely associated with morbidity and mortality by cardio- and cerebrovascular diseases. It is well-known that the protective effects of polyphenols in vivo depend on the grade how they are extracted from food and on their intestinal absorption, metabolism, and biological action with target tissues. The aim of this review was to summarise the relation between polyphenols of different plant sources and stroke in human intervention studies, animal models, and in vitro studies.

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Section: Dietary Polyphenols and Cvdmentioning

confidence: 99%

Section: Dietary Polyphenols and Cvdmentioning

confidence: 99%

Section: Dietary Polyphenols and Cvdmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Dietary Polyphenols in the Prevention of Stroke

Tressera-Rimbau

Arranz

Eder

et al. 2017

Oxidative Medicine and Cellular Longevity

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“…It is well known that polyphenols increase endothelial synthesis of NO and cause NO-mediated endotheliumdependent relaxation, reducing blood pressure [55,56]. In a previous study, we observed that systolic blood pressure decreased by a mean of 4 mmHg during the na-beer intervention, suggesting that the nonalcoholic fraction of beer, composed mainly of polyphenols, reduces blood pressure, and since blood pressure did not change after consumption of alcoholic beer, ethanol seems to act as an antagonist of the hypotensive effect of nonalcoholic compounds of beer.…”

Section: Discussionmentioning

confidence: 99%

A discovery‐driven approach to elucidate urinary metabolome changes after a regular and moderate consumption of beer and nonalcoholic beer in subjects at high cardiovascular risk

Quifer-Rada

Chiva‐Blanch

Jáuregui

et al. 2017

Molecular Nutrition Food Res

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New players in the relationship between diet and microbiota: the role of macromolecular antioxidant polyphenols

et al. 2020

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Purpose: Solid evidence has emerged supporting the role of polyphenols and fibers as gut microbiota modulators. These studies have been limited to the data available in food composition databases, which did not include the food content of non-extractable polyphenols (NEPP). The main objective of this work is to quantify the intake of the different types of dietary polyphenols including NEPP and to evaluate their impact on the composition and activity of the intestinal microbiota.Methods: Cross-sectional descriptive study conducted on a sample of 147 adults with no declared pathologies. Dietary intake has been registered by a semi quantitative Food Frequency Questionnaire (FFQ) and transformed into extractable (EPP) and NEPP, and dietary fibers based on available databases. Major phylogenetic types of the intestinal microbiota were determined by qPCR and fecal SCFA quantification was performed by gas chromatography.Results: NEPP account for two thirds of the total polyphenols intake. A combined analysis by stepwise regression model including all dietary fiber and (poly)phenols has identified hydrolysable (poly)phenol (HPP) intake, as the best predictor of Bacteroides-Prevotella-Porphyromonas group 2 and Bifidobacterium levels in feces. Also, HPP were positively associated with butyric acid, while insoluble fiber was identified as a predictor of propionic acid in feces. Conclusion:The intake of macromolecular (poly)phenols could contribute to modulate the gut microbiota by increasing the levels of certain intestinal microorganisms with proven health benefits.

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Effect of dietary polyphenols on cardiovascular risk

Cited by 5 publications

References 6 publications

Dietary Polyphenols in the Prevention of Stroke

Dietary Polyphenols in the Prevention of Stroke

A discovery‐driven approach to elucidate urinary metabolome changes after a regular and moderate consumption of beer and nonalcoholic beer in subjects at high cardiovascular risk

New players in the relationship between diet and microbiota: the role of macromolecular antioxidant polyphenols

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