Effect of dietary organic selenium on milk selenium concentration and antioxidant and immune status in midlactation dairy cows

Gong, Jian-Sheng; Ni, Lulu; Deng-feng, Wang; Binlin, Shi; Yan, Shijuan

doi:10.1016/j.livsci.2014.10.003

Cited by 59 publications

(48 citation statements)

References 36 publications

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“…Furthermore, the apparent absorption of total Se was 59.7 and 49.5% for HMSeBA and SS at 0.3 mg of Se/kg of DM, respectively, with a significant difference between the organic and inorganic Se sources in the current study. The present results confirmed better bioavailability of HMSeBA compared with SS, which agrees with the superior absorption of organic Se sources Gong et al, 2014).…”

Section: Short Communicationsupporting

confidence: 88%

“…Two principal forms of Se are currently used: inorganic Se, such as sodium selenite (SS) or sodium selenite, and organic Se, such as selenium yeast (SY). Many previous studies have shown that SY, the most widely used organic Se feed supplementation, has higher bioavailability (Briens et al, 2014) and is associated with a larger increase in Se in milk (Givens et al, 2004) and blood (Walker et al, 2010) and a greater improvement in antioxidant status (Gong et al, 2014;Sun et al, 2017).…”

Section: Short Communicationmentioning

confidence: 99%

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Short communication: Effects of different selenium supplements on rumen fermentation and apparent nutrient and selenium digestibility of mid-lactation dairy cows

Wei

Wang

Liu

et al. 2019

Journal of Dairy Science

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The aim of this study was to evaluate the dosedependent effects of a hydroxy-analog of selenomethionine (HMSeBA) on rumen fermentation, apparent nutrient digestibility, and total selenium absorption in mid-lactation dairy cows, and to compare the effects with those of sodium selenite (SS). Fifty mid-lactation dairy cows with similar milk yields, days in milk, and parity were randomly assigned to 1 of 5 treatments according to a randomized complete block design. The cows were fed a basal diet containing 0.06 mg/kg dry matter (DM) of Se (control) or the same basal diet supplemented with SS, yielding 0.3 mg of Se/kg of DM (SS-0.3), or HMSeBA, yielding 0.1, 0.3, or 0.5 mg of Se/ kg of DM (SO-0.1, SO-0.3, and SO-0.5, respectively), during the experimental period. The final content of Se in control, SS-0.3, SO-0.1, SO-0.3, and SO-0.5 was 0.06, 0.34, 0.15, 0.33, and 0.52 mg of Se/kg of DM.The experiment lasted for 10 wk, with a pretrial period of 2 wk. Supplementation with HMSeBA altered rumen fermentation by linearly increasing total volatile fatty acids and the molar proportions of propionate and butyrate but decreasing rumen pH, ammonia content, and the ratio of acetate to propionate. Compared with SS, HMSeBA enhanced the molar proportion of propionate in the rumen and the apparent digestibility of crude protein, neutral detergent fiber, acid detergent fiber, and selenium. We demonstrated that HMSeBA promoted rumen fermentation, apparent nutrient digestibility, and selenium absorption, implying that HMSeBA has a greater apparent absorption than SS.

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Section: Short Communicationsupporting

confidence: 88%

Section: Short Communicationmentioning

confidence: 99%

Short communication: Effects of different selenium supplements on rumen fermentation and apparent nutrient and selenium digestibility of mid-lactation dairy cows

Wei

Wang

Liu

et al. 2019

Journal of Dairy Science

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“…Similar results were observed in the kidney of chickens when fed excess Se (Xu et al ). GSH‐Px is an important Se‐containing enzyme in the blood and tissues of animals (Gong et al ) and its activities were increased in plasma, liver, testis, thyroid and pituitary of pigs fed 3.0 mg/kg dietary Se (Zhou et al ). In our study excess dietary Se improved ( P < 0.05) GSH‐Px in the bursa of Fabricius at days 28 and 42.…”

Section: Resultsmentioning

confidence: 99%

Supranutritional dietary selenium depressed expression of selenoprotein genes in three immune organs of broilers

Tang

Huang

Wang

et al. 2016

Animal Science Journal

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The objective of this study was to investigate the effects of supranutritional dietary selenium (Se) on selenoproteins expression in three immune organs of chickens. A total of 160 1-day-old male Cobb broilers were randomly divided into two groups and fed a Se-deficient corn-soybean basal diet supplemented with 0.3 (adequate) and 3.0 (excess) mg/kg Se for 42 days. Immune organs were collected, and effects of supranutritional Se on messenger RNA abundance of 23 selenoprotein genes and eight inflammation-related genes were compared at day 42. Also enzyme activities were measured at days 14, 28 and 42. The results showed supranutritional dietary Se depressed growth performance of chicken and down-regulated nine and three selenoprotein genes in thymus and spleen, respectively, and only Sepp1 was up-regulated in the bursa of Fabricius. Also three, three and seven inflammation-related genes were up-regulated in three organs, respectively. Supranutritional Se elevated (P < 0.05) activities of superoxidase dismutase, total antioxidant capacity and glutathione peroxidase, mainly in early stages. In summary, supranutritional Se resulted in down-regulation of selenoprotein genes and up-regulation of inflammation-related genes in three immune organs of chicken, which indicated potential roles of those selenoprotein genes in immune organs of the chicken.

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“…In a similar study, Holstein cows' diet was supplemented with either Se yeast or selenite. Results showed that Se yeast may be more effective than sodium selenite in improving the antioxidant status and increasing the whole blood and milk Se concentrations of dairy cows [148]. A daily supplementation of 1-6 mg organic selenium to the feed of dairy cows increased the selenium content of milk from 8 µg kg -1 to 94 µg kg -1 in 8 weeks [96].…”

Section: Food Fortification: Meat Milk and Eggsmentioning

confidence: 99%

Selenium in Soil-Crop-Animal System: A Holistic Perspective to Manage Animal and Human Health

Saha¹

2017

IJAAS

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Selenium (Se) dependent enzymes play important roles in physiological functions such as thyroid hormone metabolism, strengthens anti-oxidant defense system and immune system. However, about 800 million people worldwide are believed to be deficient in Se which is attributed to low Se levels in the soil. This is because Se in plant and animal products in human diet depends upon the available Se in the soil. Deficiency of Se can be prevented or treated by adequate dietary intake or through direct supplementation. There have been reports that patients with dilated cardiomyopathy, HIV viral loads and cancer have responded to Se supplementation. However, food fortification has been found to be more efficient than supplementation. Both agronomic biofortification and genetic biofortification have been used to increase Se content of food crops and animal products. Genetic engineering makes use of key genes of Se hyperaccumulators to increase Se accumulating potential of food crops. Agronomic biofortification increases Se content of food crops by adding Se rich fertilizers to the soil or foliar application of Se. Selenium can also be added to animal diets or feedstuff to increase Se content of meat, eggs, and milk. Although inorganic forms of Se are approved as feed additives, they are less efficient than organic sources such as selenomethionine (SeMet) which is the dominant form in plants and animals. Animal products have been found to have higher Se content than plant products with fish having the highest Se content. Fruits and vegetables have a low content of Se probably because of their low protein content. Recommendations for dietary intake of Se vary with country, age and sex. There are concerns that the present recommended Se daily allowance may not be adequate due to discovery of other selenoenzymes with higher Se requirements than gluthathione peroxidase. There may be a need to review the current recommended daily allowance for Se in order to improve human health.

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Effect of dietary organic selenium on milk selenium concentration and antioxidant and immune status in midlactation dairy cows

Cited by 59 publications

References 36 publications

Short communication: Effects of different selenium supplements on rumen fermentation and apparent nutrient and selenium digestibility of mid-lactation dairy cows

Short communication: Effects of different selenium supplements on rumen fermentation and apparent nutrient and selenium digestibility of mid-lactation dairy cows

Supranutritional dietary selenium depressed expression of selenoprotein genes in three immune organs of broilers

Selenium in Soil-Crop-Animal System: A Holistic Perspective to Manage Animal and Human Health

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