Effect of dietary lysine on muscle protein turnover in growing chickens

Tesseraud, Sophie; Larbier, M.; Chagneau, Anne-Marie; Geraert, P. A.

doi:10.1051/rnd:19920209

Cited by 40 publications

(29 citation statements)

References 8 publications

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“…Other researchers, such as Sibbald & Wolynetz (1986), Tesseraud et al (1992), Holsheimer & Ruensink (1993), Scheuermann et al (1995), Edwards et al (1999), Eits et al (2002), and Ajinomoto (2009) observed that increasing lysine levels Kubena et al (1972), Summers & Leeson (1985), Summers et al (1992), Conhalato (1998), and Eits et al (2002) also did not observe any reduction in fat deposition when feeding broilers with increasing lysine levels during the starter phase, which is consistent with our results. On the other hand, Gous & Morris (1985), Holsheimer & Ruensink (1993), Scheuermann et al (1995), Hurwitz et al (1998), and Ajinomoto (2009) concluded that increasing lysine levels during this phase reduced body fat deposition in broilers.…”

Section: Protein and Fat Depositionsupporting

confidence: 92%

Effects of dietary digestible lysine levels on protein and fat deposition in the carcass of broilers

Tavernari¹,

Buteri²,

Rostagno³

et al. 2009

Rev. Bras. Cienc. Avic.

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Section: Protein and Fat Depositionsupporting

confidence: 92%

Effects of dietary digestible lysine levels on protein and fat deposition in the carcass of broilers

Tavernari¹,

Buteri²,

Rostagno³

et al. 2009

Rev. Bras. Cienc. Avic.

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“…Lysine supplementation to a lysine-deficient diet otherwise balanced in terms of other amino acids significantly increased the amounts of protein synthesised and degraded in chicken skeletal muscle (Tesseraud et al, 1992(Tesseraud et al, , 1996a(Tesseraud et al, , 1996b(Tesseraud et al, and 2001. Similar results have been demonstrated Nutrients for production and product quality in the growing pig (Salter et al, 1990) and in humans (Conway et al, 1980;Meredith et al, 1986).…”

Section: Muscle and Adipose Tissue Metabolismsupporting

confidence: 67%

Responses to nutrients in farm animals: implications for production and quality

Hocquette

Tesseraud

Cassar-Malek

et al. 2007

Animal

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It is well known that any quantitative (energy and protein levels) and qualitative (nature of the diet, nutrient dynamic) changes in the feeding of animals affect metabolism. Energy expenditure and feed efficiency at the whole-body level, nutrient partitioning between and within tissues and organs and, ultimately, tissue and organ characteristics are the major regulated traits with consequences on the quality of the meat and milk produced. Recent progress in biology has brought to light important biological mechanisms which explain these observations: for instance, regulation by the nutrients of gene expression or of key metabolic enzyme activity, interaction and sometimes cross-regulation or competition between nutrients to provide free energy (ATP) to living cells, indirect action of nutrients through a complex hormonal action, and, particularly in herbivores, interactions between trans-fatty acids produced in the rumen and tissue metabolism. One of the main targets of this nutritional regulation is a modification of tissue insulin sensitivity and hence of insulin action. In addition, the nutritional control of mitochondrial activity (and hence of nutrient catabolism) is another major mechanism by which nutrients may affect body composition and tissue characteristics. These regulations are of great importance in the most metabolically active tissues (the digestive tract and the liver) and may have undesirable (i.e. diabetes and obesity in humans) or desirable consequences (such as the production of fatty liver by ducks and geese, and the production of fatty and hence tasty meat or milk with an adapted fatty acid profile).

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“…Protein fractional synthesis rates (FSR) were measured in vivo according to the flooding-dose method (Garlick et al 1980 and. This method, previously validated in chickens by Muramatsu and Okumura (1985), has been adapted in our laboratory (Tesseraud et al 1992). At 20 min before slaughter, birds that had not eaten for 4 to 6 h received a single intravenous injection (0.8 mL/100 g body weight) of a radioactivephenylalanine solution (150 mmol/L; 1.67-1.85 kBq/L).…”

Section: Methodsmentioning

confidence: 99%

Chronic Heat Exposure Alters Protein Turnover of Three Different Skeletal Muscles in Finishing Broiler Chickens Fed 20 or 25% Protein Diets

Temim¹,

Chagneau²,

Peresson³

et al. 2000

The Journal of Nutrition

124

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Heat-exposed chickens exhibit a lower growth rate and a depressed protein retention which may result from an alteration in protein metabolism. A high-protein diet seems to be beneficial under hot conditions because it tends to improve growth. Effects of high ambient temperature (32 vs. 22°C) and dietary crude protein (25 vs. 20%) on muscle protein turnover were investigated in finishing broiler chickens. At 5-6 wk of age, protein synthesis was measured in vivo in the Pectoralis major, Sartorius and Gastrocnemius muscles (flooding dose of [ 3 H]-phenylalanine). Protein breakdown was determined in the same muscles as the difference between protein synthesis and deposition. Chronic heat stress markedly reduced protein synthesis, irrespective of muscle type (P Ͻ 0.05). This was mainly related to the lower capacity for protein synthesis (muscle RNA/Protein) (P Ͻ 0.01). Chronic heat exposure also decreased protein breakdown in the P. major and Sartorius; this effect was not observed in the Gastrocnemius. Protein synthesis was more affected than breakdown, leading to reduced protein deposition, at least in the P. major and Gastrocnemius muscles. Increasing dietary protein content had no significant impact on muscle protein turnover. Particularly at 32°C, the high-protein diet did not significantly modify either protein synthesis, ribosomal capacity or translational efficiency. However, it favored muscle protein deposition, which was probably related to reduced proteolysis. In conclusion, we showed that chronic heat exposure decreased muscle protein deposition, mainly by reducing protein synthesis. Under these conditions, the impaired protein synthesis was not restored by a 5% higher protein intake. J.

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Effect of dietary lysine on muscle protein turnover in growing chickens

Abstract: Summary ― Day-old male chickens were fed ad libitum isoenergetic diets containing 20% crude protein but differing in their lysine content (from 6.5 up to 11.3 g/kg). At

Cited by 40 publications

References 8 publications

Effects of dietary digestible lysine levels on protein and fat deposition in the carcass of broilers

Effects of dietary digestible lysine levels on protein and fat deposition in the carcass of broilers

Responses to nutrients in farm animals: implications for production and quality

Chronic Heat Exposure Alters Protein Turnover of Three Different Skeletal Muscles in Finishing Broiler Chickens Fed 20 or 25% Protein Diets

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