Effect of dietary carotene on fertility of high-yielding dairy cows

Ascarelli, I.; Edelman, Z.; Rosenberg, Miriam; Folman, Y.

doi:10.1017/s0003356100025307

Cited by 32 publications

(9 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…His report was followed by numerous studies to confirm the effects of BC [3,4]. Although the positive effects of the dietary intake of BC on the conception rate after AI were reproduced by some investigators [43,44], many authors reported no effect due to BC supplementation on AI conception rates [45][46][47][48]. Folman et al [49] pointed out that in some of the experiments in which the basal plasma BC levels were lower than 50 µg/dl, BC supplementation did significantly increase fertility; however, in no case was fertility affected when plasma BC levels exceeded 150 µg/dl.…”

Section: Effects Of Vitamin a In Artificial Insemination (Ai) In Cattlementioning

confidence: 99%

The Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

Ikeda

Kitagawa

Imai

et al. 2005

Journal of Reproduction and Development

View full text Add to dashboard Cite

Abstract. Vitamin A is one of the micronutrients which have been implicated in cattle reproduction.In cattle, ingested vitamin A, mainly as β-carotene (BC) from forages and retinol ester from formula feed, is metabolized and transported to the oocytes and cumulus-granulosa cells in ovarian follicles through binding to various interacting molecules. The active form of vitamin A, retinoic acid (RA), functions as a regulator of gene expression in these targets. Early research showed the positive effects of vitamin A supplementation on bovine fertility in artificial insemination, and several studies on effects of vitamin A metabolites used in other artificial reproductive techniques (ART), including superovulation, ovum pick up, and in vitro maturation culture have provided evidence for the specific roles of vitamin A in oocyte cytoplasmic maturation (acquisition of developmental competence of oocytes during their meiotic maturation period for the embryonic development after fertilization). BC may enhance cytoplasmic maturation by its antioxidant properties which cannot be replaced by RA. Furthermore, RA may promote cytoplasmic maturation of bovine oocytes via its modulatory effects on the gene expression of gonadotrophin receptors, midkine, cyclooxygenase-2, and nitric oxide synthase in cumulus-granulosa cells. Key words: Vitamin A, Cattle, Oocyte, Cytoplasmic maturation (J. Reprod. Dev. 51: [23][24][25][26][27][28][29][30][31][32][33][34][35] 2005) itamin A is one of the fat-soluble vitamins and is well known to regulate development, cellular growth and differentiation, and tissue function [1,2]. Since the earliest research into vitamin A function in cattle reproduction [3,4], vitamin A and its metabolites (Fig. 1) have been tested in various artificial reproduction techniques (ART) in cattle. It has been found so far that vitamin A and its metabolites affect ovarian follicular growth [5] and steroidogenesis [6], oviductal and uterine environments [7,8], immune functions [9-11], oocyte maturation, and embryo and conceptus development [12].Oocytes are formed during fetal life and are arrested at the prophase stage of the first meiotic division. After puberty, the fully grown oocyte arrested at the first meiotic prophase, the germinal vesicle stage, in the last folliclular wave [13] within the estrous cycle resumes meiosis in response to a preovulatory luteinizing hormone (LH) surge and reaches the metaphase stage of the second meiotic division. This process is called oocyte maturation [14] and is considered to involve not only the resumption of meiosis (nuclear maturation) but also the acquisition of developmental competence ( c y t o p l a s m i c m a t u r a t i o n ) f o r e m b r y o n i c d e v e l o p m e n t a f t e r f e r t i l i z a t i o n [ 1 5 , 1 6 ] .

show abstract

Section: Effects Of Vitamin a In Artificial Insemination (Ai) In Cattlementioning

confidence: 99%

The Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

Ikeda

Kitagawa

Imai

et al. 2005

Journal of Reproduction and Development

View full text Add to dashboard Cite

show abstract

“…Although xanthophylls, mainly lutein, account for the main carotenoid in forages, ß-carotene is the main carotenoid deposited in bovine tissues [27] and milk [11,15]. Many studies on ß-carotene in bovines have been conducted to improve fertility [2] or reduce reproductive disorders [18] and mammary infections [6,7]. Furthermore, since the amount of ß-carotene deposited in adipose tissue and/or secreted in milk fat varies widely according to the carotenoid content in the feed, it plays a role in the sensorial and nutritional value of the final carcass and dairy products [22].…”

Section: Introductionmentioning

confidence: 99%

Effects of mountain grassland maturity stage and grazing management on carotenoids in sward and cow's milk

et al. 2006

View full text Add to dashboard Cite

-Carotenoids are involved in the sensorial and nutritional values of dairy products. In grazing systems, both herbage maturity stage and grazing management may affect the amount of carotenoid ingested, thus these factors may affect carotenoid concentrations in milk. Two homogenous plots of mountain grassland (1.4 and 2.0 ha) were grazed during two cycles of growth by 6 dairy cows in mid lactation, in strip (SG) and rotational grazing (RG), respectively. We monitored the changes in carotenoid concentrations in sward and milk, measured by HPLC twice a week. Seven carotenoids were identified in the sward: violaxanthin, antheraxanthin, epilutein, lutein, zeaxanthin, ß-carotene and 13-cis ß-carotene. Forage quality decreased throughout the course of the first growth stage, but carotenoid concentration in sward did not significantly change. In early regrowth, forage quality was high and the concentration of ß-carotene and xanthophylls also tended to be higher. Carotenoid concentrations in sward were not affected by grazing management, averaging 350 µg per g DM. The carotenoids identified in milk were β-carotene (75%) and lutein (25%). A significant decrease in ß-carotene concentration in milk was observed throughout the course of the first growth stage, from 5.37 to 3.87 µg per g fat, whereas it increased to 4.91 µg per g fat in early regrowth. β-carotene concentration in milk was not affected by grazing management, averaging 4.72 and 5.03 µg per g fat for RG and SG, respectively. However, lutein concentration was slightly lower for RG than for SG, averaging 1.39 and 1.74 µg per g fat, respectively. It is concluded that carotenoids in milk were only slightly affected by herbage maturity stage, and to a lesser extent by grazing management. caroténoïdes du lait pourraient dépendre du stade de l'herbe et du mode de pâturage, qui conditionnent la quantité et la qualité de l'ingéré. Pour valider cette hypothèse, deux prairies naturelles de montagne homogènes, de 1,4 et 2,0 ha, ont été exploitées par 6 vaches en milieu de lactation, en pâturage tournant rapide (SG) et lent (RG), respectivement, pendant deux cycles de végétation. Nous avons suivi l'évolution des teneurs en caroténoides de l'herbe et du lait, déterminées par HPLC sur deux prélèvements par semaines. Dans l'herbe, sept caroténoïdes ont été identifiés : violaxanthine, anthéraxanthine, épilutéine, lutéine, zéaxanthine, ß-carotène et 13-cis ß-carotène. Au cours du premier cycle de végétation, la valeur nutritive de l'herbe a fortement diminué, mais sa teneur en caroténoïdes n'a pas été significativement modifiée. Les teneurs en ß-carotène et xanthophylles et la valeur nutritive de l'herbe étaient les plus élevées au début du deuxième cycle. La concentration en caroténoïdes de l'herbe n'a pas été affectée par le mode de pâturage, et était en moyenne de 350 µg par g MS. Dans le lait, les caroténoïdes identifiés ont été le ß-carotène (75 %) et la lutéine (25 %). La concentration en ß-carotène dans le lait a diminué significativement de 5,37 à 3,87 µg par g M...

show abstract

“…Moreover, it has been suggested that b-carotene, a precursor to vitamin A, may have a unique role in reproduction (Lothammer 1978;Olentine 1982;Ascarelli et al 1985).…”

Section: Introductionmentioning

confidence: 99%

Vitamin A and β‐Carotene Levels in Plasma, Corpus Luteum and Follicular Fluid of Cyclic and Pregnant Cattle

Haliloğlu

Başpınar

Serpek

et al. 2002

Reprod Domestic Animals

View full text Add to dashboard Cite

This study was carried out to examine the relationship between the corpus luteum (CL) weight, CL and follicle diameters and progesterone, beta-carotene and vitamin A levels in reproductive organs of cattle obtained from the slaughterhouse. The beta-carotene and vitamin A levels were determined in plasma, CL and follicular fluid (FF) using a spectrophotometric method at different stages of the oestrous cycle (n=40) and at 3-6 months of pregnancy (n=10). The diameters of the CL and follicle were measured using ultrasonography. Plasma progesterone concentrations were determined by an enzyme immunoassay method. The vitamin A levels of the plasma, CL and FF were not related to each other. The highest plasma vitamin A levels were observed in the proestrus and oestrus, at which periods follicular activity dominates. The vitamin A levels in the CL and FF were negatively related to the weight and diameter of the CL and the diameter of follicle, respectively. In contrast to vitamin A, beta-carotene concentrations of plasma, CL and FF were significantly correlated with each other. The highest beta-carotene levels in the plasma, CL and FF were found during pregnancy when there is maximal luteal function, and the beta-carotene level of the CL was significantly correlated with the weight and diameter of CL. Furthermore, the intrafollicular beta-carotene level was negatively correlated with the follicle diameter. There was a positive correlation between plasma progesterone level and the weight and diameter of the CL, but a negative correlation between plasma progesterone level and follicle diameter. Moreover, plasma, FF and CL beta-carotene levels were positively correlated with plasma progesterone levels. This study revealed that beta-carotene levels in the plasma, CL and FF were influenced by the stage of the oestrous cycle or the pregnancy and were related to bovine luteal function without depending on vitamin A.

show abstract

Effect of dietary carotene on fertility of high-yielding dairy cows

Cited by 32 publications

References 18 publications

The Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

The Roles of Vitamin A for Cytoplasmic Maturation of Bovine Oocytes

Effects of mountain grassland maturity stage and grazing management on carotenoids in sward and cow's milk

Vitamin A and β‐Carotene Levels in Plasma, Corpus Luteum and Follicular Fluid of Cyclic and Pregnant Cattle

Contact Info

Product

Resources

About