Effect of diastolic dysfunction on intraventricular velocity behavior in early diastole by flow mapping

Berlot, B; Mur, José Luis Moya; Jug, Borut; Muñoz, Daniel; Megías, Alicia; Rojo, Eduardo Casas; Fernández-Golfín, Covadonga; Zamorano, José Luís

doi:10.1007/s10554-019-01612-x

Cited by 6 publications

(7 citation statements)

References 25 publications

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“…The reduction of E/eʹ exhibits the ability of the heart to fill at lower pressures during the recovery period after exercise. Exercise-induced LVFP changes are likely to be caused by alteration in myocardial relaxation [5,12]. Consistent with this, our data showed that the changes of lateral mitral annular eʹ velocity, which reflect LV relaxation, were also different between CH and CA following exercise, while the changes of mitral E velocity were similar between the races.…”

Section: Discussionsupporting

confidence: 88%

“…This suggests the different change of LVFP between races may be caused by disproportionate changes in mitral annular eʹ velocity and mitral E velocity between CH and CA subjects following exercise. As previously reported, LV diastolic function and LVFP were associated with HR [39], hemodynamics [5,28,29], exercise capacity [17,24], LV deformation [33,43,45] and BMI [35,47]. We also investigated whether baseline HR, BP, aerobic capacity, DWS, and BMI might produce different influences on ΔE/eʹ between races.…”

Section: Discussionmentioning

confidence: 59%

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Racial Differences in Left Ventricular Filling Pressure Following Acute Aerobic Exercise Between Chinese and Caucasians

Sun

Yan

Lane

et al. 2022

J. of SCI. IN SPORT AND EXERCISE

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Background Left ventricular filling pressure (LVFP) is an important early indicator of heart failure that is more prevalent in Caucasians than Chinese. Exercise-induced change in LVFP may provide more incremental information to assess diastolic function. But it was unknown whether there was difference in LVFP following acute exercise between Caucasians and Chinese. Purpose The purpose of this study was to investigate the change of LVFP following an acute 45-min aerobic exercise in healthy Caucasian and Chinese individuals. Methods Sixty participants (30 Caucasians and 30 Chinese, half was male, respectively) performed an acute bout of aerobic exercise at 70% of heart rate reserve. Hemodynamics, Left ventricle (LV) morphology and function parameters were measured at baseline, then at 30-min and 60-min post-exercise. Results There was a similar LV ejection fraction, LV fraction shorten, lateral E/eʹ and lateral eʹ between Chinese and Caucasians at baseline. There was a significant race-by-time interaction in lateral E/eʹ and lateral eʹ between Chinese and Caucasians from pre-exercise to 30 min and 60 min after acute aerobic exercise. The ΔE/eʹ was significant correlated with baseline systolic blood pressure. Conclusion The change of LVFP was different between Chinese and Caucasians following acute aerobic exercise. The racial differences may be primarily caused by the changes of LV relaxation following exercise, baseline systolic blood pressure may also contribute to the differences.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 59%

Racial Differences in Left Ventricular Filling Pressure Following Acute Aerobic Exercise Between Chinese and Caucasians

Sun

Yan

Lane

et al. 2022

J. of SCI. IN SPORT AND EXERCISE

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“…[1][2][3] Vector flow mapping (VFM) is a novel validated echocardiographic technology enabling visualization of intraventricular flow velocity vectors using color Doppler and speckle-tracking data without angle dependency. 4,5 Normal values for EL are scant, and the relation between age and EL remains uncertain. We performed VFM in consecutive volunteers to define the relationship of EL to age and to standard echocardiographic parameters in normal patients.…”

mentioning

confidence: 99%

Diastolic Left Ventricular Energy Loss: Relation to Age, Phase of Diastole, and Flow Velocity

Adabifirouzjaei

Igata

Strachan

et al. 2021

Journal of the American Society of Echocardiography

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“…During the E-lling phase, average EL was lower in the HCM group compared with the H-LVH group, which was associated with reduced LVEDVI and intraventricular velocity gradient from base to apex (Vbp) determined by multiple stepwise regression analysis. The diastolic intraventricular velocity gradient derived from VFM could be useful for estimating impaired LV relaxation and local ow dynamics in the ventricular chambers [13,14].…”

Section: Discussionmentioning

confidence: 99%

Quantitative Analysis of Left Ventricular Flow Dynamics in Hypertrophic Cardiomyopathy using vector flow mapping: Comparison with hypertensive LV hypertrophy

Wang

Bai

et al. 2022

Preprint

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Background Hypertrophic cardiomyopathy (HCM) and secondary hypertensive LV hypertrophy (H-LVH) differ in pathophysiology. However, the differences and mechanisms of their blood flow fields have not been well studied. This study aimed to assess energy loss (EL), circulation, vortex area, vorticity and intraventricular velocity gradient between these two hypertrophy types. Methods Vector flow mapping (VFM) echocardiography was performed in 35 healthy participants, 25 HCM patients, and 24 H-LVH patients. Circulation, vortex area and vorticity during atrial filling (A-filling), isovolumic contraction (IVC) and ejection period were measured, as well as intraventricular velocity gradient during the E-filling period and average energy loss (EL-ave) during one cardiac cycle for each period. Measurements were averaged over three cardiac cycles. Results The “absent E-filling vortex ring” phenomenon was found in 8 HCM cases (32%), with significantly increased EL-ave during the A-filling period and relatively reduced diastolic intraventricular velocity gradient between the base and the apex (Vbp) compared with patients with normal E-filling vortex ring. EL-ave during the E-filling period was weaker in HCM than in the control and H-LVH groups. From A-filling to ejection, EL-ave was obviously increased in the HCM and H-LVH groups compared to the control group. Multivariable analyses revealed that EL-ave during the E-filling period in the HCM and H-LVH groups was affected by different heart structure-related factors and had a good diagnostic efficiency in differentiating HCM from H-LVH. Conclusion Differences in abnormal hemodynamics observed between HCM and H-LVH are reflected in both VFM-derived parameters, especially non-physiological vortices and early filling EL, which is closely related to special morphology. EL during E-filling as a novel parameter may be may be useful in differentiating HCM from hypertensive LVH.

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Effect of diastolic dysfunction on intraventricular velocity behavior in early diastole by flow mapping

Cited by 6 publications

References 25 publications

Racial Differences in Left Ventricular Filling Pressure Following Acute Aerobic Exercise Between Chinese and Caucasians

Racial Differences in Left Ventricular Filling Pressure Following Acute Aerobic Exercise Between Chinese and Caucasians

Diastolic Left Ventricular Energy Loss: Relation to Age, Phase of Diastole, and Flow Velocity

Quantitative Analysis of Left Ventricular Flow Dynamics in Hypertrophic Cardiomyopathy using vector flow mapping: Comparison with hypertensive LV hypertrophy

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