Effect of dexmedetomidine vs. acepromazine–methadone premedication on limb to lung circulation time in dogs

Rocchi, Attilio; Ambriskó, Tamás Dezső; Moens, Yves

doi:10.1016/j.tvjl.2012.06.055

Cited by 3 publications

(3 citation statements)

References 23 publications

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“…This, in turn, produces sedation and muscular relaxation while also reducing motor activity. However, the secondary effects described include hypotension, bradycardia, and a slight depression of the respiratory system . These changes were observed in experimental Group A in our study.…”

Section: Discussionsupporting

confidence: 50%

Effect of different anesthetic mixtures—ketamine‐xylazine, ketamine‐acepromazine and tiletamine‐zolazepam—on the physiological and blood biochemistry parameters of male rhesus monkeys (Macaca mulatta) at different ages

Hernández-Godínez

Jaime²,

Poblano

et al. 2019

Anim Models and Exp Med

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Background Anesthetic agents are commonly utilized in the handling of non‐human primates for prevent the stress caused in physical exploration or physical restrain. For this reason, the objective of this work was to describe the effect of age and dissociative anesthetics (ketamine and tiletamine), and their combinations with acepromazine, xylazine and zolazepam, on the physiological and blood biochemical parameters in Macaca mulatta . Methods Eighty male Macaca mulatta were divided into four experimental groups depending on the anesthetic mixture applied. Each group of 20 males was divided into five sub‐groups according to age. Physiological parameters were recorded every 5 minutes during a 30‐minute period. A blood sample was drawn to analyze blood biochemistry. Results Statistical analyses revealed significant differences in the physiological parameters between the ketamine‐acepromazine and ketamine‐xylazine groups compared to the control group. The analysis of blood biochemistry found significant differences by age and by anesthetic mixture among all groups. Conclusion These findings contribute to standardizing this animal model in biological research.

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Section: Discussionsupporting

confidence: 50%

Effect of different anesthetic mixtures—ketamine‐xylazine, ketamine‐acepromazine and tiletamine‐zolazepam—on the physiological and blood biochemistry parameters of male rhesus monkeys (Macaca mulatta) at different ages

Hernández-Godínez

Jaime²,

Poblano

et al. 2019

Anim Models and Exp Med

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“…Recently it has been shown that dexmedetomidine (0.01 mg kg −1 IM) increases the blood circulatory time compared to acepromazine (0.04 mg kg −1 IM) and methadone (0.2 mg kg −1 IM) premedication in dogs (Rocchi et al. ). The slower circulation prolongs the time period until the peripherally administered drug reaches an anaesthetic level in the brain.…”

Section: Discussionmentioning

confidence: 99%

“…While in the aforementioned studies acepromazine (0.05 mg kg À1 IM) was used as premedication, we used an a 2 -agonist, namely medetomidine (0.01 mg kg À1 IM). Recently it has been shown that dexmedetomidine (0.01 mg kg À1 IM) increases the blood circulatory time compared to acepromazine (0.04 mg kg À1 IM) and methadone (0.2 mg kg À1 IM) premedication in dogs (Rocchi et al 2013). The slower circulation prolongs the time period until the peripherally administered drug reaches an anaesthetic level in the brain.…”

Section: Alfaxalone and Propofol Dose Ratesmentioning

confidence: 99%

Comparison of the effects of propofol or alfaxalone for anaesthesia induction and maintenance on respiration in cats

Campagna

Schwarz

Keller

et al. 2015

Veterinary Anaesthesia and Analgesia

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Postinduction apnoea in dogs premedicated with acepromazine or dexmedetomidine and anaesthetized with alfaxalone or propofol

Bigby

Beths

Bauquier

et al. 2017

Veterinary Anaesthesia and Analgesia

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Effect of dexmedetomidine vs. acepromazine–methadone premedication on limb to lung circulation time in dogs

Cited by 3 publications

References 23 publications

Effect of different anesthetic mixtures—ketamine‐xylazine, ketamine‐acepromazine and tiletamine‐zolazepam—on the physiological and blood biochemistry parameters of male rhesus monkeys (Macaca mulatta) at different ages

Effect of different anesthetic mixtures—ketamine‐xylazine, ketamine‐acepromazine and tiletamine‐zolazepam—on the physiological and blood biochemistry parameters of male rhesus monkeys (Macaca mulatta) at different ages

Comparison of the effects of propofol or alfaxalone for anaesthesia induction and maintenance on respiration in cats

Postinduction apnoea in dogs premedicated with acepromazine or dexmedetomidine and anaesthetized with alfaxalone or propofol

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