Effect of desflurane on changes in regional cerebral oxygenation in patients undergoing one-lung ventilation is equivalent to the effect of propofol

Sato, Satoshi; Edanaga, Mitsutaka; Kondo, Masako; Yamakage, Michiaki

doi:10.1016/j.resp.2021.103798

Cited by 3 publications

(2 citation statements)

References 30 publications

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“…However, Sato et al . in a randomized clinical trial noted that propofol and desflurane induced similar alterations in BO during one-lung ventilation [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

“…Akdogan et al found that the use of intravenous propofol was correlated with increased risk of BO decrease over 20% as compared to inhalation with sevoflurane (50% vs. 33%, p < 0.05) in patients undergoing thoracic surgery (lobectomies, chest wall resections, pneu-monectomies) [11]. However, Sato et al in a randomized clinical trial noted that propofol and desflurane induced similar alterations in BO during one-lung ventilation [12]. Nevertheless, reports of BO measurements in thoracic surgery are less common than other surgical fields, such as cardiac surgery.…”

Section: Discussionmentioning

confidence: 99%

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Comparison of peripheral blood saturation with brain oxygenation in patients undergoing thoracic surgery

Kubisa¹,

Lesińska²,

Safranow³

et al. 2023

kitp

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Introduction Near-infrared spectroscopy (NIRS) is a non-invasive method of regional tissue oxygenation measurement. Intraoperative use of NIRS to monitor brain oxygenation (BO) during surgery might be beneficial to identify cerebral desaturations. Aim To compare peripheral blood saturation (SpO 2 ) with BO measurements and evaluate the utility of BO in thoracic surgery. Material and methods We took BO and SpO 2 measurements in a group of 100 patients undergoing standard thoracic surgery. Measurements were made every 15 minutes. The Mann-Whitney U test was used to compare study groups. Spearman’s rank correlation coefficient was used to determine correlation between studied parameters. Results We found a negative correlation between patients’ age and BO at the beginning of surgery. Operations lasted between 30 and 200 minutes. We found a positive correlation between BO and SpO 2 between 15 and 90 minutes of surgery. Subsequently, BO remained at a low level while SpO 2 returned to baseline values. Higher minimum SpO 2 values were noted in patients undergoing left-sided procedures. Conclusions Cerebral oxygenation does not return to baseline values until the end of the surgery as opposed to the SpO 2 . Furthermore, both SpO 2 and BO correlate negatively with the overall duration of thoracic surgery. In addition, after 90 minutes of surgery, SpO 2 stopped reflecting brain oxygenation.

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“…However, Sato et al . in a randomized clinical trial noted that propofol and desflurane induced similar alterations in BO during one-lung ventilation [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%