Effect of depressive and anxiety symptoms during pregnancy on risk of obstetric interventions

Bayrampour, Hamideh; Salmon, Charleen; Vinturache, Angela; Tough, Suzanne

doi:10.1111/jog.12683

Cited by 58 publications

(54 citation statements)

References 41 publications

(94 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Depression in mothers before and after childbirth is a major public health concern, with consequences on pregnancy outcome , mother affective status , and child behavioral and emotional development . The prevalence of postpartum depression (PPD) is estimated at around 10–20% and well‐established risk factors include presence of antepartum depression, psychiatric history, low self‐esteem, stressful life events and lack of social support .…”

Section: Introductionmentioning

confidence: 99%

Delineating the association between mode of delivery and postpartum depression symptoms: a longitudinal study

Eckerdal

Georgakis

Kollia

et al. 2018

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

show abstract

Section: Introductionmentioning

confidence: 99%

Delineating the association between mode of delivery and postpartum depression symptoms: a longitudinal study

Eckerdal

Georgakis

Kollia

et al. 2018

Acta Obstet Gynecol Scand

View full text Add to dashboard Cite

show abstract

“…The following maternal and neonatal characteristics were included as independent variables or potential confounders [ 29 , 30 , 32 , 46 – 49 ]: parity (nulliparous, multiparous); care setting at the onset of labour (midwife-led, obstetrician-led), maternal age (< 20, 20–24, 25–29, 30–34, 35–39, ≥40 years); ethnic background (Dutch, non-Dutch); degree of urbanisation (urban, intermediate, rural); socioeconomic status (high, medium, low); gestational age (37 + 0–37 + 6, 38 + 0–40 + 6, 41 + 0–41 + 6, ≥42 weeks); and birth weight (< 2.3rd, <10th, >90th, > 97.7th percentile). Ethnic background was reported by the care provider and was defined as Dutch or non-Dutch, because of inconsistencies in recording non-Dutch subgroups.…”

Section: Methodsmentioning

confidence: 99%

Regional variations in childbirth interventions in the Netherlands: a nationwide explorative study

Seijmonsbergen-Schermers

Zondag

Nieuwenhuijze

et al. 2018

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

BackgroundAlthough interventions in childbirth are important in order to prevent neonatal and maternal morbidity and mortality, non-indicated use may cause avoidable harm. Regional variations in intervention rates, which cannot be explained by maternal characteristics, may indicate over- and underuse. The aim of this study is to explore regional variations in childbirth interventions in the Netherlands and their associations with interventions and adverse outcomes, controlled for maternal characteristics.MethodsChildbirth intervention rates were compared between twelve Dutch regions, using data from the national perinatal birth register for 2010–2013. All single childbirths from 37 weeks’ gestation onwards were included. Primary outcomes were induction and augmentation of labour, pain medication, instrumental birth, caesarean section (prelabour, intrapartum) and paediatric involvement. Secondary outcomes were adverse neonatal and maternal outcomes. Multivariable logistic regression analyses were used to adjust for maternal characteristics. Associations were expressed in Spearman’s rank correlation coefficients.ResultsMost variation was found for type of pain medication and paediatric involvement. Epidural analgesia rates varied from between 12 and 38% (nulliparous) and from between 5 and 14% (multiparous women). These rates were negatively correlated with rates of other pharmacological pain relief, which varied from between 15 and 43% (nulliparous) and from between 10 and 27% (multiparous). Rates of paediatric involvement varied from between 37 and 60% (nulliparous) and from between 26 and 43% (multiparous). For instrumental vaginal births, rates varied from between 16 and 19% (nulliparous) and from between 3 and 4% (multiparous). For intrapartum caesarean section, the variation was 13–15% and 5–6%, respectively. A positive correlation was found between intervention rates in midwife-led and obstetrician-led care at the onset of labour within the same region. Adverse neonatal and maternal outcomes were not lower in regions with higher intervention rates. Higher augmentation of labour rates correlated with higher rates of severe postpartum haemorrhage.ConclusionsMost variation was found for type of pain medication and paediatric involvement, and least for instrumental vaginal births and intrapartum caesarean sections. Care providers and policy makers should critically audit remarkable variations, since these may be unwarranted. Limited variation for some interventions may indicate consensus for their use. Further research should focus on variations in evidence-based interventions and indications for the use of interventions in childbirth.Electronic supplementary materialThe online version of this article (10.1186/s12884-018-1795-0) contains supplementary material, which is available to authorized users.

show abstract

“…All non-pregnant women and pregnant women were assessed using a structured interview, including the Edinburgh Postnatal Depression Scale (EPDS), Thai validated translation (Pitanupong et al 2007;Vacharaporn et al 2003) and Spielberger's State-Trait Anxiety Inventory (STAI), state version in a Thai validated translation (Spielberger and Vagg 1984;Thapinta 1991) Pregnant women with an EPDS score ≥ 11 were diagnosed as suffering from depression, either antenatal (T1) or postpartum (T2) (Pitanupong et al 2007;Vacharaporn et al 2003). The STAI had been used to assess anxiety among pregnant women (Abedian et al 2015;Bayrampour et al 2015). In nonpregnant women and pregnant women at T1 we used the Mini International Neuropsychiatric Interview (M.I.N.I) -Thai version (Kittirattanapaiboon and Khamwongpin 2005)to assess the diagnosis of Ba life time history of mood disorders^(namely major depressive disorder, bipolar disorder or dysthymia) and Ba life time history of depression^(namely major depressive disorder or dysthymia).…”

Section: Clinical Assessmentsmentioning

confidence: 99%

IgM-mediated autoimmune responses to oxidative specific epitopes, but not nitrosylated adducts, are significantly decreased in pregnancy: association with bacterial translocation, perinatal and lifetime major depression and the tryptophan catabolite (TRYCAT) pathway

et al. 2017

View full text Add to dashboard Cite

Immunoglubulin (Ig)M responses directed to oxidative specific epitopes (OSEs) and nitric oxide (NO)-adducts are significantly associated with major depression and physio-somatic symptoms. End of term serum IgM responses to OSEs and NO-adducts were assayed in pregnant women with (n = 24) and without prenatal depression (n = 25) as well as in 24 non-pregnant women. Associations of IgM/IgA responses to Gram-negative gut commensal bacteria (leaky gut index) and IgA/IgM responses to tryptophan catabolites (TRYCATs) were analyzed. IgM responses to OSEs, but not NO-adducts, were significantly reduced at the end of term. There were no significant associations between IgM responses to OSEs and perinatal depression, whilst IgM responses to NO-adducts, especially NO-cysteinyl, were significantly associated with a lifetime major depression. IgM responses to OSEs and NO-cysteinyl were significantly associated with IgA/IgM responses to Gram-negative bacteria, especially Morganella morganii, Klebsiella pneumoniae and Citrobacter koseri. IgM responses to NO-adducts and OSEs, especially malondialdehyde and myristic acid, and C-reactive protein (CRP) were inversely associated with TRYCAT pathway activity, whilst a lifetime depression and Pseudomonas putida were positively associated. The attenuation of natural IgM-mediated responses to OSEs at the end of term may indicate lowered activity of this part of the compensatory (anti-)inflammatory reflex system and may be partly explained by lowered bacterial translocation. Increased IgM responses to NO-cysteinyl is a biomarker of lifetime depression and may be induced by bacterial translocation. Natural IgM-mediated autoimmune responses, increased nitrosylation and higher CRP levels may have negative regulatory effects on the TRYCAT pathway.

show abstract

Effect of depressive and anxiety symptoms during pregnancy on risk of obstetric interventions

Cited by 58 publications

References 41 publications

Delineating the association between mode of delivery and postpartum depression symptoms: a longitudinal study

Delineating the association between mode of delivery and postpartum depression symptoms: a longitudinal study

Regional variations in childbirth interventions in the Netherlands: a nationwide explorative study

IgM-mediated autoimmune responses to oxidative specific epitopes, but not nitrosylated adducts, are significantly decreased in pregnancy: association with bacterial translocation, perinatal and lifetime major depression and the tryptophan catabolite (TRYCAT) pathway

Contact Info

Product

Resources

About