“…In addition, long-term use of those materials has been reported to cause bone loss of residual ridge because of tissue irritation, inequitable distribution of masticatory force on denture-bearing mucosa, and malocclusion by the hard materials 5) . The clinical efficacy of denture adhesives, such as masticatory performance, retention, and stability of dentures, has been reported in various studies [6][7][8][9][10][11] , in which denture adhesives were found to improve retention and stability of both well-and ill-fitting dentures, though the efficacy was greater with ill-fitting dentures 8) . These materials are also beneficial for denture patients in regard to comfort, reduction of tissue irritation, and psychological security 12) .…”