Effect of Dentifrice Containing Fluoride and/or Baking Soda on Enamel Demineralization/ Remineralization: An in situ Study

Abstract

The additive effect of baking soda on the anticariogenic effect of fluoride dentifrice is not well established. To evaluate it, a crossover in situ study was done in three phases of 28 days. Volunteers, using acrylic palatal appliances containing four human enamel blocks, two sound (to evaluate demineralization) and two with artificial caries lesions (to evaluate remineralization), took part in this study. During each phase, 10% sucrose solution was dripped (3 times a day) only onto the sound blocks. After 10 min, a slurry of placebo, fluoride (F) or fluoride and baking soda (F+NaHCO₃) dentifrice was dripped onto all enamel blocks. The results showed a higher F concentration in dental plaque formed during treatment with F+NaHCO₃ than placebo (p<0.05), but the difference related to F dentifrice was not significant. The enamel demineralization was lower, and remineralization was greater, after treatment with F+NaHCO₃ than placebo (p<0.05), but the difference related to F dentifrice was not significant. The data suggest that baking soda neither improves nor impairs the effect of F dentifrice on reduction of demineralization and enhancement of remineralization of enamel.

Effect of starch on the cariogenic potential of sucrose

“…The use of two treatments (split-mouth) in the same intra-oral palatal appliance ( Fig. 2(A)) was supported by the absence of a cross-effect in previous studies (Cury et al 2001;Hara et al 2003;Paes Leme et al 2004;Pecharki et al 2005). On the day 13 of the experiment, the biofilm formed on the most posterior blocks of each treatment ( Fig.…”

“…Plastic meshes were fixed over the cavities to protect the enamel block surfaces from mechanical attrition, leaving a 1 mm space for accumulation of dental biofilm. Colourless or red acrylic resin was used to fix the meshes, indicating where each treatment should be made (Cury et al 2001;Paes Leme et al 2004;Pecharki et al 2005). Further details of appliance preparation are given in previous publications (Cury et al 1997(Cury et al , 2000Hara et al 2003).…”

Effect of different frequencies of fluoride dentifrice and mouthrinse administration: an in situ study

“…During 7-day lead-in and wash-out periods the volunteers brushed their teeth with a non-fluoride dentifrice to eliminate possible residual effects. 10 The products used were fluoride dentifrice (1100 ppm F as NaF, silica-based, Dentics  , Dentalprev Indústria e Comércio Ltda, São Paulo, São Paulo, Brazil) and non-fluoride dentifrice (free-fluoride, silica-based, Dentics  ), as well as fluoride mouthrinse (225 ppm F as NaF, Dentics  ). The volunteers were instructed to wear the appliances day and night and to remove them only during meals or oral care.…”

“…Mouthrinses are usually recommended for active-caries patients in addition to normal use of fluoride dentifrice. 4 In vivo [6][7][8][9] and in situ studies [10][11][12] have shown that the frequency of topical fluoride applications is of importance to the effectiveness of caries preventive measures. Mouthrinses do not increase the fluoride exposure frequency, since they are usually applied immediately after the toothbrushing procedure.…”

Progressão da lesão de cárie no esmalte dental após aplicação de compostos fluoretados e irradiação com laser de CO2

“…Isso explica a vasta utilização desta substância no cotidiano, principalmente em dentifrícios , água de abastecimento público (PARNELL et al, 2000), alimentos e bebidas preparados com água fluoretada (CURY et al, 2001), soluções para bochecho e agentes fluoretados de uso profissional, como géis e vernizes (SEPPÄ, 2001. Em conseqüência do declínio, a doença cárie tornou-se fortemente polarizada (SEPPÄ, 2001).…”