Self-lubricating NiCrBSi-Ni/MoS 2 coatings are prepared on 304 stainless steel by pre-placed laser cladding, in which Ni/MoS 2 is almost completely decomposed and the Cr x S y antifriction phase is in situ generated. Meanwhile, (Cr, Fe) 2 B and (Cr, Fe) 7 C 3 are generated from the molten pool as a result of oversaturated B and C atoms in γ-Ni and the diffusion of Fe atoms. Therefore, the composite coatings are mainly composed of γ-(Ni, Fe), (Cr, Fe) 2 B, (Cr, Fe) 7 C 3 , and Cr x S y . When compared with the substrate, the wear rate of the coatings with 20 wt-% Ni/MoS 2 is reduced by 21.16%, owing to the Cr x S y lubricating phase, while it is reduced by 25.61% for the coatings with 5 wt-% Ni/MoS 2 , owing to blocky (Cr, Fe) 2 B or (Cr, Fe) 7 C 3 hard phases. The wear mechanism of the coatings is adhesive wear and oxidative wear.