Effect of COVID-19 on colorectal cancer care in England

Turnbull, Clare

doi:10.1016/s2468-1253(21)00017-0

Cited by 12 publications

(9 citation statements)

References 9 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our observations are in line with several studies on the impact of the COVID-19 pandemic on cancer detection rate and management of oncological diseases. In accordance with our results, a strong decline in newly diagnosed cancers was observed in breast, colorectal, lung and prostate cancer in the USA and across Europe [4,5,6,7]. Recommendations on cancer management during the pandemic include the implementation of telemedicine for the outpatient treatment of cancer survivors to minimize face-to-face appointments [8].…”

Section: Discussionsupporting

confidence: 77%

The Impact of COVID-19 Pandemic on Gynecological and Breast Cancer Detection Rate: A Tertiary Center Perspective.

Knoll

Reiser

Leitner

et al. 2021

Preprint

View full text Add to dashboard Cite

Purpose: The aim of the present study was to assess the impact of postponed screening examinations and lockdown measures on gynecological and breast cancer detection rate throughout the year 2020 in a gynecological oncological center in Austria.Methods: Data of 889 patients with either newly diagnosed gynecological or breast cancer between January 2019 and December 2020 were collected. Clinical parameters including symptoms, performance status, comorbidities and referral status were compared in patients, who were newly diagnosed with cancer in the period of the first lockdown from March 2020 – April 2020 and the second lockdown from November 2020 – December 2020 and compared to the same period in 2019.Results: Our results showed a strong decline in newly diagnosed cancers during the lockdown periods: -45% in gynecological cancer and -52% in breast cancer compared to the same period in 2019. Compared to the analogue period of 2019, breast cancer patients reported significantly more tumor-associated symptoms (55% versus 31%, p=0.013) during and in between (48% versus 32%, p=0.022) the lockdowns. During the lockdown periods breast cancer patients were diagnosed with a significantly higher tumor-stage (T2-T4; p=0.047).Conclusion: Both lockdowns led to a strong decrease in newly diagnosed gynecological and breast cancers. Treatment delays in potentially curable disease could lead to inferior clinical outcomes, with the risk of missing the optimal treatment window. As the COVID-19 pandemic will be a challenge for some time to come, new strategies in patient care are needed to optimize cancer screening and management during the pandemic.

show abstract

Section: Discussionsupporting

confidence: 77%

The Impact of COVID-19 Pandemic on Gynecological and Breast Cancer Detection Rate: A Tertiary Center Perspective.

Knoll

Reiser

Leitner

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Among calculations, the COVID-19 pandemic could lead to 36 000 delayed or missed breast cancer diagnoses and 2 500 missed cases of cervical cancer in the three months from March to June 2020 [5]. Moreover, strong decline in newly diagnosed cancers was observed in breast, colorectal, lung and prostate cancer in the USA and across Europe [6][7][8][9]. Kaufman et al have shown a decrease in mean weekly numbers of newly diagnosed patients with colorectal cancer, lung cancer, pancreatic cancer, gastric cancer, esophageal cancer and breast cancer of 46.4% for the timespan of 1 March to 18 April of 2020 when compared to the weekly numbers between 6 January 2019 and 29 February 2020.…”

Section: Discussionmentioning

confidence: 99%

The impact of COVID-19 pandemic on the rate of newly diagnosed gynecological and breast cancers: a tertiary center perspective

Knoll

Reiser

Leitner

et al. 2021

Arch Gynecol Obstet

View full text Add to dashboard Cite

Purpose The aim of the present study was to assess the impact of postponed screening examinations and lockdown measures on gynecological and breast cancer diagnoses throughout the year 2020 in a gynecological oncological center in Austria. Methods Data of 889 patients with either newly diagnosed gynecological or breast cancer between January 2019 and December 2020 were collected. Clinical parameters including symptoms, performance status, comorbidities and referral status were compared in patients, who were newly diagnosed with cancer in the period of the first lockdown from March 2020 to April 2020 and the second lockdown from November 2020 to December 2020 and compared to the same period in 2019. Results Our results showed a strong decline in newly diagnosed cancers during the lockdown periods: −45% in gynecological cancer and -52% in breast cancer compared to the same period in 2019. Compared to the analogue period of 2019, breast cancer patients reported significantly more tumor-associated symptoms (55% vs. 31%, p = 0.013) during and in between (48% vs. 32%, p = 0.022) the lockdowns. During the lockdown, periods in the group of breast cancer patients’ tumor stage varied significantly compared to 2019 (T2–T4; p = 0.047). Conclusion Both lockdowns led to a strong decrease in newly diagnosed gynecological and breast cancers. Treatment delays in potentially curable disease could lead to inferior clinical outcomes, with the risk of missing the optimal treatment window. As the COVID-19 pandemic will be a challenge for some time to come, new strategies in patient care are needed to optimize cancer screening and management during the pandemic.

show abstract

“…Surgical interventions should not be limited to patients requiring urgent treatment, even during the COVID-19 pandemic [ 10 ]. Diagnostic delay may have an especially negative impact on patients with colorectal cancer [ 5 , 11 ]. Studies on surgical treatment patterns for colorectal cancer during epidemics are increasing.…”

Section: Introductionmentioning

confidence: 99%

Impact of the COVID-19 Pandemic on Surgical Treatment Patterns for Colorectal Cancer in a Tertiary Medical Facility in Korea

Choi

Park

Lee

et al. 2021

Cancers

View full text Add to dashboard Cite

Because of their reluctance to visit the hospital due to concerns about contracting coronavirus disease 2019 (COVID-19), patients with colorectal cancer have been affected by delays in care during the pandemic. This study assessed the effects of the pandemic on the clinical characteristics and surgical treatment patterns of colorectal cancer patients at a tertiary medical facility in Korea. Patients who underwent colorectal cancer surgery at our institution between March and September 2020 were analyzed. Clinicopathological and treatment characteristics were compared with those of patients who underwent surgery in 2018 and 2019. The patients who did not undergo tumor resection (4.1% vs. 1.8%, p < 0.001) and who received neoadjuvant treatment (16.7% vs. 14.7%, p = 0.039) were significantly higher during the COVID period. The minimally invasive approach was performed less during the COVID period (81.2% vs. 88%, p < 0.001). More patients in the COVID period required combined resection of organs adjacent to the tumor (4.8% vs. 2.8%, p = 0.017). Surgical aggressiveness, as shown by the proportion of patients undergoing minimally invasive surgery and adjacent organ resection, was significantly influenced by the pandemic. In addition, resectability decreased during the COVID period. These characteristics will likely influence long-term oncological outcomes, indicating the need for long-term monitoring of this cohort.

show abstract

Effect of COVID-19 on colorectal cancer care in England

Cited by 12 publications

References 9 publications

The Impact of COVID-19 Pandemic on Gynecological and Breast Cancer Detection Rate: A Tertiary Center Perspective.

The Impact of COVID-19 Pandemic on Gynecological and Breast Cancer Detection Rate: A Tertiary Center Perspective.

The impact of COVID-19 pandemic on the rate of newly diagnosed gynecological and breast cancers: a tertiary center perspective

Impact of the COVID-19 Pandemic on Surgical Treatment Patterns for Colorectal Cancer in a Tertiary Medical Facility in Korea

Contact Info

Product

Resources

About