Effect of compounds of Galla chinensis on remineralization of enamel surface in vitro

Cheng, Lei; Li, Jiyao; Hao, Yuqing; Zhou, Xuedong

doi:10.1016/j.archoralbio.2010.03.014

Cited by 42 publications

(45 citation statements)

References 19 publications

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“…Cheng et al 19) have observed the morphology, mineral composition and the crystallite sizes of surface enamel crystals treated by GA, and proposed the GA might affect the mineral ions deposit on the surface layer and then modified the remineralization of initial dental caries. What is more, GA is a type of polyphenol compounds.…”

Section: Discussionmentioning

confidence: 99%

Control of hydroxyapatite crystal growth by gallic acid

Tang

Cheng

et al. 2015

Dent. Mater. J.

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The purpose of this study is to detect the effect of gallic acid (GA) on hydroxyapatie crystal growth and find the mechanism of the regulation. We evaluated the morphology of HAP crystals grown under various amounts of GA (0, 0.05, 1, and 4 gL −1 ). Subsequently, the chemical composition, crystal size and the morphology were investigated via the energy-dispersive X-ray spectrometer, attenuated total fourier transform infrared spectroscopy, thermogravimetric analysis, X-ray diffraction analysis, transmission electron microscope and scanning electron microscopy. In all groups, the Ca/P ratio was closed to 1.67. In the absence of GA, crystals did not arrange, while in the presence of GA, crystals tended to form spherules. The size of the crystals decreased with the concentration of GA increased. These results indicated the role of GA on the growth and morphology of hydroxyapatite crystals, which might be the key mechanism for gallic acid regulating the mineralization.

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Section: Discussionmentioning

confidence: 99%

Control of hydroxyapatite crystal growth by gallic acid

Tang

Cheng

et al. 2015

Dent. Mater. J.

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“…GCE was prepared as described in previous studies [Cheng et al, 2009]. In brief, Galla chinensis was dried at 60 ° C for 3 days, powdered, double extracted with distilled water, dissolved in ethanol and subsequently GCE was recovered by evaporation of the ethanol.…”

Section: Gce Samplesmentioning

confidence: 99%

Effect of Galla Chinensis on Growth and Metabolism of Microcosm Biofilms

et al. 2011

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Galla chinensis extract (GCE) interferes with de- and remineralization of dental enamel and the growth and metabolism in planktonic bacteria. However, no information is available on GCE effects on biofilms formed with saliva as inoculum. The aim of the current experiments was to investigate the effects of GCE at different stages of salivary microcosm biofilm formation. Biofilms formed on glass or enamel surfaces were treated with GCE solutions at different concentrations and at different time points. Effects were assessed by lactic acid formation and colony-forming unit (CFU) counts of the biofilms. The results showed that GCE treatments inhibited growth and acid metabolism of both nascent and mature microcosm biofilms. Pretreatment of the substratum with GCE solutions inhibited growth and lactic acid production of biofilms grown on enamel, but had little effects on biofilms formed on glass surfaces. A maximum GCE effect was found when biofilms, on either surface type, were treated after 8 h of formation with 40 h of subsequent growth. In medium with sucrose-fermenting biofilms, low concentrations of GCE (0.2 and 0.1 mg/ml) inhibited acid production without killing bacteria of the biofilm. Differences were found in GCE effects on biofilms formed with saliva from different donors, with reductions in acid formation and CFU values ranging between 0 and 78%. In conclusion, bioactive components in GCE reduce or inhibit both growth and lactic acid formation in biofilms.

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“…Natural Products An interesting addition to remineralizing agents are plant-derived natural products that have demonstrated the ability to beneficially shift the de-/remineralization caries equilibrium. Among the most promising is Galla chinensis, a leaf gall produced by parasitic aphids, which has been found to be effective in inhibiting demineralization, enhancing remineralization, and increasing the efficacy of fluoride [Cheng et al, 2008[Cheng et al, , 2010. The mechanisms are still not fully clear, but it is hypothesized that polyphenols present in G. chinensis interact with and stabilize the organic matrix remnants, thereby blocking the ion diffusion pathways, and slowing demineralization [Huang et al, 2017;Zhang et al, 2015].…”

Section: Fluoride Boostersmentioning

confidence: 99%

State of the Art Enamel Remineralization Systems: The Next Frontier in Caries Management

2018

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The principles of minimally invasive dentistry clearly dictate the need for clinically effective measures to remineralize early enamel caries lesions. While fluoride-mediated remineralization is the cornerstone of current caries management philosophies, a number of new remineralization strategies have been commercialized or are under development that claim to promote deeper remineralization of lesions, reduce the potential risks associated with high-fluoride oral care products, and facilitate caries control over a lifetime. These non-fluoride remineralizing systems can be broadly categorized into biomimetic enamel regenerative technologies and the approaches that repair caries lesions by enhancing fluoride efficacy. This paper discusses the rationale for non-fluoride remineralization and the mechanism of action, challenges, and evidence behind some of the most promising advances in enamel remineralization therapies.

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Effect of compounds of Galla chinensis on remineralization of enamel surface in vitro

Cited by 42 publications

References 19 publications

Control of hydroxyapatite crystal growth by gallic acid

Control of hydroxyapatite crystal growth by gallic acid

Effect of Galla Chinensis on Growth and Metabolism of Microcosm Biofilms

State of the Art Enamel Remineralization Systems: The Next Frontier in Caries Management

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