It was established that the long-term use of organic-mineral fertilization systems formed the highest biological productivity of sugar beet. When applying N53Р42K42 + 6.7 t/ha of manure per 1 ha of crop rotation, the yield of sugar beet was 46.9 t/ha, sugar content – 16.5%, sugar collection – 7.74 t/ha, N53Р42K42 + by-products are respectively 41.7 t/ha, 16.3% and 6.80 t/ha. The specified fertilization systems increased the yield of roots by 2.2-2.5 times, sugar collection by 2.1-2.4 times, compared to the control without fertilizers. The use of organic-mineral fertilization systems for 50 years ensured the maximum energy productivity of sugar beet. When applying N53P42K42 + 6.7 t/ha of manure per 1 ha of crop rotation, the output of bioethanol was 3.66 t/ha, biogas – 1980 m3/ha, total energy output – 135 GJ/ha, N53P42K42 + by-products - respectively 3.25 t/ha, 1850 m3/ha and 122 GJ/ha. Long-term application of fertilizers increased the energy productivity of sugar beet compared to the control without fertilizers by more than 2 times.