Abstract:Background:Colchicine is a natural alkaloid derived from autumn crocus; it is used in the treatment of gout and in preventing familial Mediterranean fever attacks. It accumulates in many organs such as spleen and may lead to their damage. Aim: This work aimed to study short and long duration effects of colchicine administration on the structure of the spleen of the adult male albino rat. Material and Methods: Forty-five adult male albino rats were used in this study, aged from 4-6 months, weighting 150 -180 gm… Show more
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