Effect of Coffee and Tea on Serum Lipids in the Rat

Akinyanju, P. A.; Yudkin, John

doi:10.1038/214426b0

Cited by 35 publications

(14 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our laboratory has demonstrated that green tea catechins have a variety of biological activities, including antibacterial (1-3), antioxidative (4, 5), antitumor (6) and hypocholesterolemic (7) activities. There have been many reports that green tea and oolong tea decrease plasma lipids in rodents and humans (8)(9)(10)(11)(12)(13)(14). However, few investigators have reported on the effect of black tea on plasma lipids (15-18), and there have been even fewer reports on the reduction of plasma lipids.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effect of Black Tea Polyphenols on Plasma Lipids in Cholesterol-Fed Rats.

Matsumoto

Okushio

Hara

1998

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

View full text Add to dashboard Cite

SummaryThe influence of black tea polyphenols on plasma lipid levels was investigated in rats fed a 15% lard and 1% cholesterol diet. Our laboratory has demonstrated that green tea catechins have a variety of biological activities, including antibacterial (1-3), antioxidative (4, 5), antitumor (6) and hypocholesterolemic (7) activities. There have been many reports that green tea and oolong tea decrease plasma lipids in rodents and humans (8)(9)(10)(11)(12)(13)(14). However, few investigators have reported on the effect of black tea on plasma lipids (15-18), and there have been even fewer reports on the reduction of plasma lipids. In this study, we investigated the effects of black tea polyphenols on plasma lipids. Materials and methodsPreparation of black tea polyphenols, instant black tea and epigallocatechin gallate. Black tea polyphenols (BTP) were prepared according to the following method: 2kg of instant black tea (IBT) dissolved in 20L of hot water was extracted with ethyl acetate (9L) in order to obtain the polyphenolic fraction. The solid recovered from the solvent was dissolved in 200mL of water and 300mL of acetone, and the resulting solution was washed twice with 1,500mL of chloroform 30times 337

show abstract

Section: Discussionmentioning

confidence: 99%

“…There have been many reports that green tea and oolong tea decrease plasma lipids in rodents and humans (8)(9)(10)(11)(12)(13)(14). However, few investigators have reported on the effect of black tea on plasma lipids (15)(16)(17)(18), and there have been even fewer reports on the reduction of plasma lipids.…”

Section: Lesterol Ratmentioning

confidence: 99%

Effect of Black Tea Polyphenols on Plasma Lipids in Cholesterol-Fed Rats.

Matsumoto

Okushio

Hara

1998

Journal of Nutritional Science and Vitaminology, J Nutr Sci Vit

View full text Add to dashboard Cite

show abstract

“…Green tea has recently received much attention as a protective agent against cardiovascular disease (Imai and Nakachi, 1995;Kono et al, 1996;Tsubono and Tsugane, 1997;Aneja et al, 2004;Stephanou, 2004;Townsend et al, 2004), as important targets of preventive medicine. Early evidence showed the beneficial effects of green tea on the cardiovascular system; rabbits or rats given a tea supplement to an atherogenic diet had reduced serum lipoproteins and incidence of atherosclerosis (Young et al, 1967;Akinyanju and Yudkin, 1967). Green tea extract was also shown to lower plasma cholesterol and triglyceride levels in rats (Muramatsu et al, 1986;Ikeda et al, 2005).…”

Section: Introductionmentioning

confidence: 97%

Protective effects of EGCg or GCg, a green tea catechin epimer, against postischemic myocardial dysfunction in guinea-pig hearts

et al. 2007

View full text Add to dashboard Cite

“…Tea had the opposite effect, and they commented: "Presumably, tea contains a substance that acts to decrease serum lipids more strongly than caffeine acts to increase them." 14 Recently, Buda et al (unpublished data) have shown that decaffeinated black tea has a sedative effect on the electroencephalograph of conscious cats, and Enslen and Wurzner (unpublished data) have described a modest reduction of the blood pressure of spontaneously hypertensive rats when given decaffeinated black tea. They propose that the decaffeination brings out the weak physiological effects of other substances present in tea, most likely the bioflavonoids.…”

mentioning

confidence: 99%

“…l2 The following year, Young et al 13 reported that rabbits given a tea supplement to an atherogenic diet had lower serum lipoproteins and less atherosclerosis than those on the diet alone. Akinyanju and Yudkin 14 found that coffee enhanced the increase of blood lipids induced by an atherogenic diet; an effect that was abol- VOL 6, No 3, MAY-JUNE 1984 ished by decaffeination. Tea had the opposite effect, and they commented: "Presumably, tea contains a substance that acts to decrease serum lipids more strongly than caffeine acts to increase them."…”

mentioning

confidence: 99%

Reduction of chronic psychosocial hypertension in mice by decaffeinated tea.

Henry¹,

Stephens‐Larson²

1984

Hypertension

View full text Add to dashboard Cite

SUMMARY The effects of decaffeinated green tea on CBA mice have been contrasted with those of water during 3 to 5 months of exposure to various intensities of social stress. Intensity was modified by using different types of caging: Henry-Stephens complex population cages for maximum stress, open field population cages for intermediate levels, and siblings in standard mouse boxes for minimal stress. Two population densities were used: high, with 16 males and 16 females per population cage; and low, with approximately half this number. In three sets of experiments, 58 comparisons were made between body weight, blood pressure, pulse rate, scarring, blood urea nitrogen (BUN), adrenal and heart weights, plasma corticosterone, adult male mortality, and number of weanlings of those on decaffeinated green tea and matched groups on water. Twenty-five of the comparisons indicated less arousal with the decaffeinated green tea and in none was the water favored. Blood pressure fell from 150 to 133 mm Hg. These results support the proposal that the polyphenols (bioflavonoids) of tea may have a beneficial sedative action. (Hypertension 6: 437-444, 1984) KEY WORDS • blood pressure • adrenal weight • bioflavonoids plasma corticosterone • psychosocial stress A recent authoritative review of the physiology of human essential hypertension presents strong evidence for the etiologic role of repeated arousal of the sympathetic adrenal medullary system during episodes of social interaction. 1 We have long produced psychosocial hypertension in an animal model that applies this principle by using colonies of male and female mice competing for control of territory and nest establishment in Henry-Stephens complex population cages.2 -3 The males develop a blood pressure of 155 to 160 ± 20 mm Hg, which is significantly higher than their normal 125 ± 12 mm Hg. 4These animals also show early arteriosclerosis, 5 and there is an increase in the catecholamine-synthesizing enzymes in the adrenals 6 and in the activity of the renin-angiotensin systems.7 8 A beta-blocker, metoprolol, returns the renin and blood pressure to normal. However, adrenal cortical arousal with elevated plasma corticosterone persists, and a progressive, and often fatal, chronic interstitial nephritis gradually develops.2 9 The mechanism of the nephritis is not decided, but chronic reflux of urine, due to ernotional difficulties in urination with ensuing sensitization to Tamm Horsfall protein, is currently being studied. 10We have examined the effect of various agents on the hypertension developed under continuous psychosocial stress.2 Preliminary observations show no effect of a low salt diet,' but detailed studies of the effects of caffeine show that it intensifies the hormonal and pathophysiological changes that accompany psychosocial stress." Even decaffeinated coffee, which contains a residual 3%, that is, 16 mg/liter of the original 560 mg/liter caffeine content of brewed coffee, has a slight potentiating effect on blood pressure and on the other effects of stress. ...

show abstract

Effect of Coffee and Tea on Serum Lipids in the Rat

Cited by 35 publications

References 7 publications

Effect of Black Tea Polyphenols on Plasma Lipids in Cholesterol-Fed Rats.

Effect of Black Tea Polyphenols on Plasma Lipids in Cholesterol-Fed Rats.

Protective effects of EGCg or GCg, a green tea catechin epimer, against postischemic myocardial dysfunction in guinea-pig hearts

Reduction of chronic psychosocial hypertension in mice by decaffeinated tea.

Contact Info

Product

Resources

About