Effect of Codeine Phosphate on Developmental Stages of Forensically Important Calliphoride Fly : Chrysomya Albiceps

Fathy, Hala; Adel, Rasha; Yones, Doaa A.; Eldeek, Hanan E. M.; Tolba, Mohamed F.; Shaheen, Maha

doi:10.21608/mjfmct.2008.54085

Cited by 11 publications

(12 citation statements)

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“…These changes were in the form of deformed body segments, abnormalities in the shape of anterior and posterior spiracles. However, the same study reported that codeine accelerates the development rate during the life cycle of C. albiceps 39 . Therefore, it can be presumed that the larval deformation can indicate the deceased's poisoning with insecticides, e.g., aluminum phosphide.…”

Section: Discussionmentioning

confidence: 89%

“…The vast majority of drugs accelerate the development of larvae, while pesticides tend to delay it. Larval development can be accelerated by diazepam 26 , codeine 39,40 , heroin 41 , methamphetamine and its metabolite, p-hydroxymethamphetamine 42 . However, hydrocortisone and a barbiturate -sodium methohexital 43 and the insecticide DEET -N, N-Diethyl-meta-toluamide 44 can delay the development of y larvae.…”

Section: Discussionmentioning

confidence: 99%

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Reduced body length and morphological disorders in Chrysomya albiceps (Wiedemann, 1819) (Diptera: Calliphoridae) larvae reared on aluminum phosphide-treated rabbits

El‐Ashram¹,

Na²,

Ae³

et al. 2021

Preprint

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Assessing the post-mortem interval (PMI) based on the growth and development of insects is a critical task in forensic entomology. The rate of larvae development can be affected by a variety of toxins, including pesticides. Aluminum phosphide (AlP) is a low-cost insecticide that has yet to be entomotoxicologically tested, despite the fact that it is frequently the cause of fatal poisoning. In this study, we measured the body length of Chrysomya albiceps larvae reared on the carcasses of rabbits poisoned with AlP and analyzed the morphological changes of the larvae reared on the carcasses of rabbits poisoned with AlP. The concentration of AlP in the body of the larvae was significantly lower than in rabbit tissues. Insects from the AlP group had a significantly lower gain in body length. Furthermore, deformities in the larvae were found. Small respiratory spiracles were found, as well as a deformed small posterior end with hypogenesis of the posterior respiratory spiracles. Thus, disturbed growth and development of carrion flies found at a crime scene could indicate pesticide poisoning, such as aluminum phosphide.

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Section: Discussionmentioning

confidence: 89%

Section: Discussionmentioning

confidence: 99%

Reduced body length and morphological disorders in Chrysomya albiceps (Wiedemann, 1819) (Diptera: Calliphoridae) larvae reared on aluminum phosphide-treated rabbits

El‐Ashram¹,

Na²,

Ae³

et al. 2021

Preprint

View full text Add to dashboard Cite

show abstract

“…Forensic entomotoxicology, as a new branch of forensic entomology, studies the use of insects as alternate toxicological specimens and the effects of drugs on insect physiology (Fathy et al 2008;Amendt et al 2007). Necrophagous species include dipteran and coleopteran species are the most important orders for PMI determination in different stages of decomposition (Watson 2004).…”

Section: Introductionmentioning

confidence: 99%

“…The degree of development of insects is the main technique for estimating PMI. In this technique, the investigator calculating the maggot age by measurement of the larval length, actually the maggot age indicates the time when flies first laid their eggs on the cadaver (Amendt et al 2007;Fathy et al 2008). The ages of maggots found on a corpse can provide evidence for the estimation of a minimum PMI ranging from 24 hr.…”

Section: Introductionmentioning

confidence: 99%

“…The effects of drug/toxin on body weight and body length as well as the rate of development of insects have been investigated in several, for example; heroin, codeine, and methamphetamine decrease larval development time and increase the larval length (Fathy et al 2008;Goff et al 1991;Goff et al 1997). In most above-mentioned studies, the animal model was killed immediately after the substance injection.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of the effect of methadone and temperature on the development rate of Calliphora vicina (Diptera: Calliphoridae): A forensically important fly

et al. 2020

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Abstract. Keshavarzi D, Rassi Y, Azizi K, Oshaghi MA, Rafizadeh S, Alimohammadi AM, Namadi MS, Parkhideh SZ. 2020. Analysis of the effect of methadone and temperature on the development rate of Calliphora vicina (Diptera: Calliphoridae): A forensically important fly. Nusantara Bioscience 12: 87-91. The development rate/time of flies is a scientific method to estimate the minimum time elapsed after death. Several studies have shown that opioids and temperature affect maggot growth rates. However, there are few published data that investigate the effect of ante-mortem methadone use on larval length of Calliphora vicina (Robineau-Desvoidy). Therefore, the purpose of this research was to investigate the effect of methadone and temperature on the development rate/time of this species. During this study, four rabbits were administered 0.10, 0.50, 1.0, and 10 mg/kg of methadone via gavage over a period of 14 days, and a five rabbit, which did not receive methadone, was used as a control. The rabbits' tissues were separated and exposed to maggots for rearing. Minimum developmental times of C. vicina life stages at six constant temperature regimes were provided. From hours 48 to 96, larvae feeding on tissues containing 10 mg/kg methadone developed more rapidly than those feeding on tissues containing 0.1, 0.50, and 1 mg/kg and also from the control. In the present study, development rate of C. vicina was linearly related to temperature (R2 = 0.96, p =0.02) between 16 and 32°C. The results revealed that the differences observed in the rates of development were sufficient to alter postmortem interval estimates based on larval development by up to 24 h.

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The implication of morphometrics and growth rate of dipteran flies in forensic entomotoxicology research: a review

Bhardwaj

Sharma

Dalal

et al. 2020

Sci Nat

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Effect of Codeine Phosphate on Developmental Stages of Forensically Important Calliphoride Fly : Chrysomya Albiceps

Cited by 11 publications

References 0 publications

Reduced body length and morphological disorders in Chrysomya albiceps (Wiedemann, 1819) (Diptera: Calliphoridae) larvae reared on aluminum phosphide-treated rabbits

Reduced body length and morphological disorders in Chrysomya albiceps (Wiedemann, 1819) (Diptera: Calliphoridae) larvae reared on aluminum phosphide-treated rabbits

Analysis of the effect of methadone and temperature on the development rate of Calliphora vicina (Diptera: Calliphoridae): A forensically important fly

The implication of morphometrics and growth rate of dipteran flies in forensic entomotoxicology research: a review

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