Effect of cobalt doping on crystallinity, stability, magnetic and optical properties of magnetic iron oxide nano-particles

Anjum, Safia; Tufail, Rabia; Rashid, Khalid; Zia, Rehana; Riaz, Saira

doi:10.1016/j.jmmm.2017.02.006

Cited by 50 publications

(9 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The band gap energy of the prepared nanoparticles varied with an inverse relationship with their sizes. This is similar to what has been reported in previous studies [43].…”

Section: Resultssupporting

confidence: 93%

Synthesis of Magnetic Ferrite Nanoparticles with High Hyperthermia Performance via a Controlled Co-Precipitation Method

et al. 2019

View full text Add to dashboard Cite

Magnetic nanoparticles (MNPs) that exhibit high specific loss power (SLP) at lower metal content are highly desirable for hyperthermia applications. The conventional co-precipitation process has been widely employed for the synthesis of magnetic nanoparticles. However, their hyperthermia performance is often insufficient, which is considered as the main challenge to the development of practicable cancer treatments. In particular, ferrite MNPs have unique properties, such as a strong magnetocrystalline anisotropy, high coercivity, and moderate saturation magnetization, however their hyperthermia performance needs to be further improved. In this study, cobalt ferrite (CoFe2O4) and zinc cobalt ferrite nanoparticles (ZnCoFe2O4) were prepared to achieve high SLP values by modifying the conventional co-precipitation method. Our modified method, which allows for precursor material compositions (molar ratio of Fe+3:Fe+2:Co+2/Zn+2 of 3:2:1), is a simple, environmentally friendly, and low temperature process carried out in air at a maximum temperature of 60 °C, without the need for oxidizing or coating agents. The particles produced were characterized using multiple techniques, such as X-ray diffraction (XRD), dynamic light scattering (DLS), transmission electron microscopy (TEM), ultraviolet-visible spectroscopy (UV–Vis spectroscopy), and a vibrating sample magnetometer (VSM). SLP values of the prepared nanoparticles were carefully evaluated as a function of time, magnetic field strength (30, 40, and 50 kA m−1), and the viscosity of the medium (water and glycerol), and compared to commercial magnetic nanoparticle materials under the same conditions. The cytotoxicity of the prepared nanoparticles by in vitro culture with NIH-3T3 fibroblasts exhibited good cytocompatibility up to 0.5 mg/mL. The safety limit of magnetic field parameters for SLP was tested. It did not exceed the 5 × 109 Am−1 s−1 threshold. A saturation temperature of 45 °C could be achieved. These nanoparticles, with minimal metal content, can ideally be used for in vivo hyperthermia applications, such as cancer treatments.

show abstract

“…The band gap energy of the prepared nanoparticles varied with an inverse relationship with their sizes. This is similar to what has been reported in previous studies [43].…”

Section: Resultssupporting

confidence: 93%

Synthesis of Magnetic Ferrite Nanoparticles with High Hyperthermia Performance via a Controlled Co-Precipitation Method

et al. 2019

View full text Add to dashboard Cite

show abstract

“…41 Fantechi et al, 42 for instance, showed that the doping of iron oxide MNPs with cobalt resulted in significant increases in the coercive fields and remanent magnetizations, not observing an important effect over the saturation magnetizations. Sathya et al, 43 Anjum et al, 44 or Blanco-Gutieŕrez et al 45 reported similar influence of cobalt doping over the magnetic properties of iron oxide-based MNPs. In other works, Gabal et al 46 and Noh et al 47 have shown that the doping of iron oxide MNPs with zinc in a specific range can lead to a high increase in the saturation magnetizations.…”

Section: Introductionmentioning

confidence: 87%

Synthesis, Characterization, and Evaluation of Superparamagnetic Doped Ferrites as Potential Therapeutic Nanotools

et al. 2020

View full text Add to dashboard Cite

Magnetic nanoparticles (MNPs) are one of the most promising candidates for their use as theranostic agents in the biomedical field due to their potential as contrast agents in magnetic resonance imaging (MRI) and also as heat generators in magnetic hyperthermia treatments. However, despite the large number of publications about this topic, just some few systematic studies about the influence of MNPs composition on their theranostic capabilities have been carried out. In this work, we show a detailed methodology for the preparation of highly monodisperse iron oxide-based MNPs with different cobalt, zinc, and manganese doping extents in the superparamagnetic regime. We aim to provide the tools to control the composition of the particles, as well as for their functionalization to make them highly stable in biological-mimicking media. Procedures to measure the capability of the particles as magnetothermal and MRI negative contrast agents as well as to analyze the influence of doping on such properties are also reported. In all experiments, the applied alternating magnetic fields were within the maximum allowed amplitude, frequency, and amplitude·frequency product range for potential validation of the experimental data toward the potential translation of the present MNPs to the clinical practice.

show abstract

“… 13–18 This trend was expected even considering potential residual stress in the nanomaterials caused by gradual partial substitution of Fe 2+ species in the octahedral B sites of magnetite that possess an ionic radius (0.77 Å) by Co 2+ species with a smaller ionic radius (0.74 Å) as the lattice parameters were quite similar for magnetite (8.3963 Å) and cobalt ferrite (8.3919 Å). 13 It should be noted that, according to the literature, 17–19 several aspects ( e.g. , amorphous phases and nanoparticle size) can interfere in the resolution of XRD patterns and, therefore, on the precision of Scherrer's equation for directly measuring the average crystalline size of nanoparticles.…”

Section: Resultsmentioning

confidence: 99%

Tunable magnetothermal properties of cobalt-doped magnetite–carboxymethylcellulose ferrofluids: smart nanoplatforms for potential magnetic hyperthermia applications in cancer therapy

et al. 2021

View full text Add to dashboard Cite

show abstract

Effect of cobalt doping on crystallinity, stability, magnetic and optical properties of magnetic iron oxide nano-particles

Cited by 50 publications

References 44 publications

Synthesis of Magnetic Ferrite Nanoparticles with High Hyperthermia Performance via a Controlled Co-Precipitation Method

Synthesis of Magnetic Ferrite Nanoparticles with High Hyperthermia Performance via a Controlled Co-Precipitation Method

Synthesis, Characterization, and Evaluation of Superparamagnetic Doped Ferrites as Potential Therapeutic Nanotools

Tunable magnetothermal properties of cobalt-doped magnetite–carboxymethylcellulose ferrofluids: smart nanoplatforms for potential magnetic hyperthermia applications in cancer therapy

Contact Info

Product

Resources

About