Effect of Clinical Nursing Pathway Intervention Based on Evidence-Based Medicine on Venous Thrombosis in Long-Term Bedridden Patients

Zhang

et al. 2022

Journal of Oncology

Backgrounds To observe the value of concurrent chemoradiotherapy and clinical nursing pathway for postoperative patients with esophageal cancer (EC). Methods A total of 88 postoperative EC patients were divided into the radiotherapy group (RG group, 44 cases) and the chemoradiotherapy group (CRG group, 44 cases). The RG group received single three-dimensional conformal radiotherapy+clinical nursing pathway, and the CRG group was combined with chemotherapy on this basis. The 5-year overall survival rate, progression-free survival rate, pathological remission and survival rate, lymph node metastasis and survival rate, quality of life analysis, tumor-related factor level, and incidence of adverse reactions were compared between the two groups. Results The overall survival rates at 1, 3, and 5 years were 93.18%, 56.82%, and 50.0% in the CRG group and 86.36%, 52.27%, and 43.18% in the RG group, respectively. The 5-year progression-free survival rate of the CRG group was 60.87%, which was clearly higher than that of the RG group (33.33%). The 1-, 3-, and 5-year overall survival rates of pCR and NpCR patients were 90.48%, 80.95%, and 61.90% and 89.55%, 44.78%, and 38.81%, respectively. The overall 1-year, 3-year, and 5-year survival rates were 81.08%, 37.84, and 24.32% and 96.08%, 66.67%, and 62.75% in patients with lymph node metastasis and nonlymph node metastasis, respectively, with statistical significant differences. The emotional function, physical function, cough, pain, and eating difficulty in the CRG group were better than those in the RG group. After treatment, serum CEA, SCC, CYFRA21-1, and CA199 levels in the CRG group were obviously downregulated compared with those in the RG group. There was no obvious difference in the incidence of adverse reactions between the CRG group and the RG group. Conclusion Single radiotherapy and concurrent chemoradiotherapy can be used as effective means in the treatment of EC. Moreover, the quality of life and survival time of the concurrent chemoradiotherapy group were dramatically better than those of the single radiotherapy group, and the antitumor ability of the concurrent chemoradiotherapy group was stronger.

Section: Discussionmentioning

confidence: 99%

Study on the Application Value of Concurrent Chemoradiotherapy and Clinical Nursing Pathway for Postoperative Patients with Esophageal Cancer

Zhang

et al. 2022

Journal of Oncology

“…The "2021 Practice Standards for Infusion Therapy" [10] has encouraged patients with indwelling PICCs to perform early, normal daily activities, and mild physical exercise, but it has not specify the specific early hand activity program. There are many researches [11][12][13] on the methods and modes of limb exercise on the side of PICC catheterization worldwide, hand and upper limb exercises are widely used in clinical practice for prevention, but there is no quantitative standard for the duration, frequency, and frequency of exercise. Several previous studies [14][15][16] have reported the effects of quantified versus willful grip exercises for the prevention of PICC-related thrombosis, yet the results remain inconsistent.…”

Section: All Data Generated or Analyzed During This Study Are Include...mentioning

confidence: 99%

Quantified versus willful handgrip exercises for the prevention of PICC-related thrombosis: A meta-analysis and systematic review

Luo¹,

Jin

et al. 2023

Medicine

Background: Thrombosis is a common yet serious complication in patients with peripherally inserted central venous catheter (PICC), the prevention of thrombosis is very important to the prognosis of PICC patients. We aimed to evaluate the effects of quantified versus willful grip exercises for the prevention of PICC-related thrombosis, to provide evidence to the clinical nursing care of PICC patients.Methods: Two authors searched PubMed et al databases for randomized controlled trials (RCTs) comparing the effects of quantified versus willful grip exercises in PICC patients up to August 31, 2022. Quality assessment and data extraction were independently performed by 2 researchers, and meta-analysis was performed using RevMan 5.3 software.Results: 15 RCTs involving 1741 PICC patients were finally included in this meta-analysis. Synthesized outcomes indicated that compared with willful grip exercises, quantified grip exercises reduced the incidence of PICC-related thrombosis (odds ratio = 0.19, 95% confidence interval [CI]: 0.12-0.31) and infection (odds ratio = 0.30, 95% CI: 0.15-0.60) in PICC patients, increased the maximum venous velocity (mean difference = 3.02, 95% CI: 1.87-4.17) and mean blood flow (mean difference = 3.10, 95%CI: 1.57-4.62) in PICC patients (all P < .05). There were no publication biases amongst the synthesized outcomes (all P > .05).Conclusion: Quantified grip exercises can effectively reduce the occurrence of PICC-related thrombosis and infection, improve the venous hemodynamics. Limited by study population and regions, large-sample, and high-quality RCTs are still needed in the future to further evaluate the effects and safety of quantified grip exercises in PICC patients.Abbreviations: CI = confidence interval, OR = odds ratio, PICC = peripherally inserted central venous catheter, RCTs = randomized controlled trials.

Egyptian Journal of Health Care

“…As a component of the advancement in the field of nursing science, the traditional approach to nursing based on experience is undergoing a transformation into the modern approach of nursing that is grounded in scientific principles. There exist various sources of evidence that can be followed, which have the potential to offer a more comprehensive and scientifically informed framework for guiding nursing practice (Chen et al, 2022). DVT continues to pose a challenge for individuals, primarily due to the insufficient knowledge and inadequate implementation of preventive measures by nurses (Alyousef, et al, 2022 2022), nurses are the most suitable candidates for conducting daily assessments of DVT prophylaxis.…”

Section: )mentioning

confidence: 99%

Effect of Implementing Evidence-Based Nursing Practices Guidelines on Prevention of Deep Venous Thrombosis among Postpartum Women

Ouda Abd ELmoniem,

Fathy EL Sayed,

Mohamed Mohamed Emam

2023

Background: Postpartum deep venous thrombosis is a leading cause of maternal mortality and can carry significant long-term morbidity. Aim: was to investigate effect of implementing evidence-based nursing practices guidelines on prevention of deep venous thrombosis among postpartum women. Design: A quasi-experimental research design. Sample: A purposive sample of two groups (50 women in study group and 50 women in control group). Setting: This study was conducted at antenatal clinic and postpartum unit of