Effect of Cigarette Smoke on Salivary Total Antioxidant Capacity

Bakhtiari, Somayeh; Azimi, Somayyeh; Mehdipour, Masoumeh; Amini, Somayyeh; Elmi, Zahra; Namazi, Zahra

doi:10.15171/joddd.2015.049

Cited by 30 publications

(42 citation statements)

References 15 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bakhtiari et al confirmed that oxidative stress from smoking was not reduced even after using anti-oxidant drugs, including vitamin C (38). On the other hand, in an animal study, the activities of some antioxidant enzymes, including superoxide dismutase, catalase, and glutathione Int J High Risk Behav Addict.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Salivary Total Antioxidant Capacity in Smokers with Severe Chronic Periodontitis

Shirzaiy

Ladiz

Dalirsani

et al. 2017

Int J High Risk Behav Addict

View full text Add to dashboard Cite

Background: Smoking leads to changes in immune reaction and total antioxidant capacity. Smoking, through dysfunction of antioxidant system, plays an important role in the pathogenesis of inflammatory diseases. Objectives: The current study aimed at comparing salivary antioxidant capacity in smokers and non-smokers with severe chronic periodontitis. Patients and Methods:In this case-control study, among patients referred to Zahedan School of Dentistry without any systemic diseases, 64 patients with severe chronic periodontitis, including 27 smokers as the case group and 37 non-smokers as the control group, were selected. Stimulated salivary samples were collected and total antioxidant levels were evaluated through the Ferric reducing antioxidant power (FRAP) technique. All analyses were performed by SPSS (Ver.18) using Student's t-test, Mann Whitney test or analysis of variance (ANOVA) with significance level of 0.05 in all of the tests.

show abstract

Section: Discussionmentioning

confidence: 99%

Evaluation of Salivary Total Antioxidant Capacity in Smokers with Severe Chronic Periodontitis

Shirzaiy

Ladiz

Dalirsani

et al. 2017

Int J High Risk Behav Addict

View full text Add to dashboard Cite

show abstract

“…10 Cigarette smoke contains harmful components such as pyridine alkaloids, aromatic hydrocarbons and combustion gases; these can lead to the development of various life-threatening diseases. 15,16 Moreover, smoking has many side-effects which manifest in the oral mucosa, including delays in wound healing, periodontitis and premalignant and malignant oral lesions. 16 Due to the deleterious effects of smoking on the oral mucosa, associated salivary changes and the limited number of studies in this field, the aim of this study was to evaluate the salivary pH, BC and ALP activity of male smokers and healthy non-smokers in Hamadan, Iran.…”

mentioning

confidence: 99%

Comparison of Salivary pH, Buffering Capacity and Alkaline Phosphatase in Smokers and Healthy Non-Smokers: Retrospective cohort study

Ahmadi‐Motamayel¹,

Falsafi²,

Goodarzi³

et al. 2016

SQUMJ

View full text Add to dashboard Cite

abstract:Objectives: Saliva contains alkaline phosphatase (ALP)-a key intracellular enzyme related to destructive processes and cellular damage-and has buffering capacity (BC) against acids due to the presence of bicarbonate and phosphate ions. Smoking may have deleterious effects on the oral environment due to pH changes which can affect ALP activity. This study aimed to evaluate the salivary pH, BC and ALP activity of male smokers and healthy non-smokers. Methods: This retrospective cohort study took place between August 2012 and December 2013. A total of 251 healthy male non-smokers and 259 male smokers from Hamadan, Iran, were selected. Unstimulated whole saliva was collected from each participant and pH and BC were determined using a pH meter. Salivary enzymes were measured by spectrophotometric assay. Results: Mean salivary pH (7.42 ± 0.48 and 7.52 ± 0.43, respectively; P = 0.018) and BC (3.41 ± 0.54 and 4.17 ± 0.71; P = 0.001) was significantly lower in smokers compared to non-smokers. Mean ALP levels were 49.58 ± 23.33 IU/L among smokers and 55.11 ± 27.85 IU/L among non-smokers (P = 0.015). Conclusion: Significantly lower pH, BC and ALP levels were observed among smokers in comparison to a healthy control group. These salivary alterations could potentially be utilised as biochemical markers for the evaluation of oral tissue function and side-effects among smokers. Further longitudinal studies are recommended to evaluate the effects of smoking on salivary components.

show abstract

“…The participants were requested not to eat or drink two hours prior to saliva collection. The smokers were also prohibited from smoking for one hour prior to saliva collection [4]. To gather whole unstimulated saliva, the participants were asked to spit their saliva into 15 mL centrifuge tubes.…”

Section: Collection Of Saliva Samplesmentioning

confidence: 99%

“…There have been several studies that observed antioxidants level on human body, including in smokers. The total antioxidant capacity (TAoC) in smokers and non-smokers shower that TAoC in non-smokers was higher than that in smokers [4].…”

Section: Introductionmentioning

confidence: 96%

Analysis of the Total Antioxidant Capacity of Saliva in Smokers

Indrastiti

Rahmayanti

Soegyanto

2019

Pesqui. bras. odontopediatria clín. integr.

View full text Add to dashboard Cite

Objective: To analyze the total antioxidant capacity (TAoC) of saliva in smokers based on type of cigarette, duration and frequency of smoking. Material and Methods: 51 male smokers, aged 20-55 years were enrolled. Information regarding cigarette type and smoking duration and frequency was collected using a questionnaire. Unstimulated saliva samples were collected in the morning following fasting for 2 h, and TAoC was measured using a commercial kit. The data were evaluated through the independent t-test and Kruskal-Wallis test. Results: Mean TAoC for the consumption of Kretek cigarettes was 0.29 (±0.15) and for that of non-Kretek cigarettes was 0.36 (±0.10). Mean TAoC based on smoking duration was 0.31 (±0.14) for 5-10 years and 0.27 (±0.15) for >10 years. Median TAoC based on smoking frequency was 0.23 (0.11-0.44), 0.31 (0.06-0.64), and 0.27 (0.06-0.68) for 1-5, 6-10, and 11-20 cigarettes/day. Mean TAoC of the saliva from participants who consumed Kretek cigarettes was lower than that of the saliva from those who consumed non-Kretek cigarettes (p=0.3). Mean TAoC for a duration >10 years was lower than that for a duration of 5-10 years, although the difference between these two groups was not significant (p=0.4). Conclusion: There were tendencies of lower total antioxidant capacity on smokers with kretek type cigarettes, smoking duration >10 years and frequency of 1-5 cigarettes/day. This study indicates that the type, duration, and frequency of smoking may affect the salivary total antioxidant capacity.

show abstract

Effect of Cigarette Smoke on Salivary Total Antioxidant Capacity

Cited by 30 publications

References 15 publications

Evaluation of Salivary Total Antioxidant Capacity in Smokers with Severe Chronic Periodontitis

Evaluation of Salivary Total Antioxidant Capacity in Smokers with Severe Chronic Periodontitis

Comparison of Salivary pH, Buffering Capacity and Alkaline Phosphatase in Smokers and Healthy Non-Smokers: Retrospective cohort study

Analysis of the Total Antioxidant Capacity of Saliva in Smokers

Contact Info

Product

Resources

About