Effect of choline chloride-oxalic acid based deep eutectic solvent on the ultrasonic assisted extraction of polyphenols from Aegle marmelos

Saha, Suman; Dey, Sayan; Chakraborty, Runu

doi:10.1016/j.molliq.2019.110956

Cited by 77 publications

(52 citation statements)

References 30 publications

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“…The stretching of O-H at 3400 cm −1 appeared progressively in DESs, got higher as water content increased and became stronger in SAFA m (Figure 1b-e). Similar phenomena have been reported in choline chloride and oxalic acid, as well as in choline chloride and glycol-based DESs, and might be due to alternative possibilities for H bonding in DES upon the introduction of water [35,40]. Hammond et al (2017) have revealed that the introduction of a small quantity of water affected immensely the nanostructure of DES.…”

Section: Evaluation Of Dess Efficiencysupporting

confidence: 75%

“…The addition of water decreased DES viscosity. The application of water in DESs has been reported to weaken and disintegrate the DESs nanostructure [35,40]. In the present study, the application of water decreased the viscosity to 61.6 mPa.s at 20% (v/v), 17.36 mPa.s at 40% (v/v), 10.81 mPa.s at 60% (v/v) and 7.66 mPa.s at 80% (v/v).…”

Section: Introductionsupporting

confidence: 50%

“…However, FTIR analysis showed that the shape of spectra was kept after addition of 80% water. This indicates the tolerance of DES structure [35,52]. Nonetheless, C-H stretching weakened upon addition of water and disappeared completely in SAFA m .…”

Section: Evaluation Of Dess Efficiencymentioning

confidence: 82%

“…From spectroscopy data, it can be assumed that the strong COOH...COOH bonds in sodium acetate and formic acid were broken down during the formation of sodium acetate and formic acid mixture to produce new strong intramolecular COOH bonds. This explains the low melting point and high viscosity of the pure SAFA 0 [35]. The DESs prepared in molar and molarity ratios were encoded as SAFA0 and SAFAm, respectively.…”

Section: Ftirmentioning

confidence: 99%

“…Each DES was characterized by high viscosity ranged between 6.15 and 3651.6 mPa.s ( Table 1). The presence of carboxyl groups and alkyl chains causes extremely high viscosity [35,50]. The pure SAFA 0 (0% water content) was semi-solid at room temperature and displayed an extremely high viscosity of 3651.6 mPa.s.…”

Section: Introductionmentioning

confidence: 99%

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Recovery and Stabilization of Anthocyanins and Phenolic Antioxidants of Roselle (Hibiscus sabdariffa L.) with Hydrophilic Deep Eutectic Solvents

et al. 2020

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: Deep eutectic solvents (DESs) have got huge interest as new green and sustainable solvents for the extraction of bioactive compounds from plants in recent decades. In the present study, we aimed to investigate the effectiveness of hydrophilic DES for the extraction of anthocyanin and polyphenol antioxidants from Roselle. A natural hydrophilic DES constituted of sodium acetate (hydrogen bond acceptor) and formic acid (hydrogen bond donor) designed to evaluate the total phenolic compound (TPC), total flavonoid (TFC), total anthocyanin (TACN), 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and ferric reducing antioxidant power (FRAP) values of Roselle. Distilled water, 70% ethanol, and 80% methanol used as conventional solvents for comparison. The results indicated that the DES prepared in molarity ratio (SAFAm) was the most efficient. Subsequently, this prominent DES selected for the optimization and the optimum extraction conditions were 1:3.6 molarity ratio, 0% additional water, and 10 mL solvent. TPC, TFC, TACN, FRAP, and DPPH radical scavenging at the optimum point were 233.26 mg GAE/g, 10.14 mg ECE/g, 10.62 mg D3S/g, 493.45 mmol ISE/g, and 343.41 mmol TE/g, respectively. The stability tests showed that anthocyanins were more stable in SAFAm. These findings revealed that SAFAm is an effective green solvent for the extraction of polyphenols from various plants.

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Section: Evaluation Of Dess Efficiencysupporting

confidence: 75%

Section: Introductionsupporting

confidence: 50%

Section: Evaluation Of Dess Efficiencymentioning

confidence: 82%

Section: Ftirmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Recovery and Stabilization of Anthocyanins and Phenolic Antioxidants of Roselle (Hibiscus sabdariffa L.) with Hydrophilic Deep Eutectic Solvents

et al. 2020

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Binary and Ternary Deep Eutectic Solvents for Methylene Green Electropolymerization on Multiwalled Carbon Nanotubes: Optimization, Characterization and Application

Almeida,

Pedro,

Buoro

et al. 2024

Chemistry A European J

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Choline chloride (ChCl) based binary and ternary deep eutectic solvents (DES) were evaluated for methylene green electropolymerization with oxalic acid (OA) and ethylene glycol (EG) as hydrogen bond donors. Binary DES ChCl:OA in molar ratios 1:1 and 2:1 and ChCl:EG 1:2 and ternary DES (tDES) in different molar ratios and percentages of water were evaluated. The highest polymer growth was in ChCl:OA:EG‐tDES with added water, that had a lower viscosity and higher ionic conductivity when associated with HCl as dopant. This enhanced the formation of more cation radicals and, consequently, more polymer formation. The PMG/MWCNT/GCE‐tDES sensor was successfully applied to the simultaneous determination of 5‐aminosalicylic acid (5‐ASA) and acetaminophen (APAP) by differential pulse voltammetry in the concentration range 2 µM ‐ 200 µM, with detection limits of 0.37 µM and 0.49 µM for 5‐ASA and APAP, respectively. The sensor demonstrated good repeatability, reproducibility and stability, and was successfully applied in pharmaceutical formulations.

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Menthol‐based deep eutectic solvents as green extractants for the isolation of omega‐3 polyunsaturated fatty acids from Perna canaliculus

Anstiss

Weber

Baroutian

et al. 2023

J of Chemical Tech & Biotech

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BACKGROUND Marine‐derived omega‐3 polyunsaturated fatty acids (PUFA) are used globally as food supplements for their anti‐inflammatory properties and to reduce the risk of obesity, cardiovascular diseases, and cancer. New Zealand green‐lipped mussels (Perna canaliculus) contain diverse valuable compounds, including omega‐3 PUFA. The most abundant omega‐3 PUFA in Perna canaliculus are eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which account for many of the health benefits accredited to these mussels. This research investigates the feasibility of using deep eutectic solvents (DESs) to isolate EPA and DHA from Perna canaliculus. RESULTS Twenty‐two hydrophobic DESs were screened using COSMO‐RS software to predict their affinity for EPA and DHA. Nine top‐ranked DESs were used for experimental extraction validation. The results exposed that the extraction capacity of the menthol: lidocaine DES (1:1 M ratio) for EPA and DHA was superior (172.04 μg EPA g−1 dry weight (DW) of biomass and 602.79 μg DHA g−1 DW) amongst other DESs. This was a considerably higher extraction yield than that observed using ethanol (95.65 μg EPA g−1 DW and 311.49 μg DHA g−1 DW). The optimisation of the menthol: lidocaine ratio identified a 1:2 M ratio as the optimal composition for this DES. The highest yields of EPA (267.59 μg g−1 DW) and DHA (1014.84 μg g−1 DW) were obtained by this optimised DES ratio at optimum extraction conditions (extraction temperature 65 °C, extraction time 2.12 h, and biomass loading 5 w/v%). The EPA and DHA showed good stability in the menthol: lidocaine DES over 7 days. This DES also showed good reusability, with a comparable extraction efficiency being observed after five extraction cycles. CONCLUSION This research revealed that menthol‐based DES can be a potential green solvent for the extraction of EPA and DHA from New Zealand green‐lipped mussels and it may be applicable for extracting other bioactive compounds with similar characteristics. © 2023 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).

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Effect of choline chloride-oxalic acid based deep eutectic solvent on the ultrasonic assisted extraction of polyphenols from Aegle marmelos

Cited by 77 publications

References 30 publications

Recovery and Stabilization of Anthocyanins and Phenolic Antioxidants of Roselle (Hibiscus sabdariffa L.) with Hydrophilic Deep Eutectic Solvents

Recovery and Stabilization of Anthocyanins and Phenolic Antioxidants of Roselle (Hibiscus sabdariffa L.) with Hydrophilic Deep Eutectic Solvents

Binary and Ternary Deep Eutectic Solvents for Methylene Green Electropolymerization on Multiwalled Carbon Nanotubes: Optimization, Characterization and Application

Menthol‐based deep eutectic solvents as green extractants for the isolation of omega‐3 polyunsaturated fatty acids from Perna canaliculus

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