Effect of Cholesterol and Boiled Extract of Red Pepper on the Level of some Hormones and Weights of Local Male Rabbits

Abstract

The current study was designed to investigate the effect of cholesterol supplementation at a dose of (260 mg/kg ration) and boiled extract of red pepper at a dose of (100 mg/kg body weight) on the Testosterone hormone, Thyroid stimulating hormone or Thyrotropin, thyroxine, thyronine, and it is effects on the body weights of male rabbits after 4, 8 weeks of the start of treatment. Forty local male rabbits aged (8-10) months old were randomly divided into four groups (10 animals/ group) to be treated as follows: First group: Standard ration and distilled water represented as control groups. Second group: Standard ration plus cholesterol at the dose (260 mg/ kg ration) and distilled water. Third group: Standard ration with drinking red pepper fruit boiled extract at the dose (100 mg/ kg body weight). Fourth group: Standard ration plus cholesterol (260 mg / kg ration) in addition to drinking red pepper fruits boiled extract at a dose of (100 mg/kg body weight). All groups were treated daily for eight weeks. Results showed that cholesterol treatment caused significant decrease(P≤0.05) in the hormones level, with a significant increase (P≤0.05) on the body weights of treated rabbit after 4 and 8 weeks. Furthermore, treatment with red pepper boiled extract led to a significant increase (P≤0.05) on the levels of the studied hormones, and a significant decrease (P≤0.05) in the body weights of treated rabbits.

Comparison of the effect of the alcoholic extract of leaves and fruits of hawthorn plant Crataegus azarolus with the drug simvastatin in its effect in reducing cardiovascular disease in male rabbits with experimental fat disorder

“…DiscussionAs mentioned above, hyperlipidemia events in rabbits have led to a rise in total cholesterol, triglyceride, low density lipoprotein, very low density lipoprotein, low concentrations of high density lipoprotein Both serum and liver extracts. Where the results of the current study agreed with the results of Al-Ashlash[21] in the study and attributed the researcher caused the high concentration of cholesterol in the group treated with cholesterol to a defect in the process of fat metabolism, or a defect in the process of absorption and subtraction of steroids or perhaps because of low concentration of bile salte. Simvastatin and its role in lowering body fat levels have been agreed with Tikrit Journal…”