Effect of Chloride Concentration on the Aqueous Corrosion of a Magnesium Alloy

Jones, D. de G.; Masterson, H.G.

doi:10.1038/191165a0

Cited by 11 publications

(6 citation statements)

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“…Note that Mg is a biocompatible trace element vital for many bodily functions and that the reaction of Mg microparticles with water is used to generate propulsion. 23,24 …”

Section: Resultsmentioning

confidence: 99%

“…The template-synthesized PEDOT/Au microtubes serve as robust microcontainers for loading the Mg microparticles, whereas Au is used as a model cargo for in vivo biodistribution study. Note that Mg is a biocompatible trace element vital for many bodily functions and that the reaction of Mg microparticles with water is used to generate propulsion. , …”

Section: Results and Discussionmentioning

confidence: 99%

“…Note that Mg is a biocompatible trace element vital for many bodily functions and that the reaction of Mg microparticles with water is used to generate propulsion. 23,24 Figure 1c and Supporting Figure 1 display the top and side views, respectively, of Mg particles infiltrated into a PEDOT/ Au microtube. These scanning electron microscopy (SEM) images and engergy-dispersive X-ray (EDX) mapping confirm that the microtube can be successfully loaded with Mg particles, while the interparticle space could be potentially filled with therapeutic or imaging payloads.…”

Section: Resultsmentioning

confidence: 99%

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Enteric Micromotor Can Selectively Position and Spontaneously Propel in the Gastrointestinal Tract

et al. 2016

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The gastrointestinal (GI) tract, which hosts hundreds of bacteria species, becomes the most exciting organ for the emerging microbiome research. Some of these GI microbes are hostile and cause a variety of diseases. These bacteria colonize in different segments of the GI tract dependent on the local physicochemical and biological factors. Therefore, selectively locating therapeutic or imaging agents to specific GI segments is of significant importance for studying gut microbiome and treating various GI-related diseases. Herein, we demonstrate an enteric micromotor system capable of precise positioning and controllable retention in desired segments of the GI tract. These motors, consisting of magnesium-based tubular micromotors coated with an enteric polymer layer, act as a robust nanobiotechnology tool for site-specific GI delivery. The micromotors can deliver payload to particular location via dissolution of their enteric coating to activate their propulsion at the target site towards localized tissue penetration and retention.

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“…Note that Mg is a biocompatible trace element vital for many bodily functions and that the reaction of Mg microparticles with water is used to generate propulsion. 23,24 …”

Section: Resultsmentioning

confidence: 99%

Section: Results and Discussionmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Enteric Micromotor Can Selectively Position and Spontaneously Propel in the Gastrointestinal Tract

et al. 2016

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“…[61]. The influence of anions, in particularly chlorides, on the corrosion of metals has been well studied [62][63][64], and such anions have gathered significant interest in the field of Mg biocorrosion.…”

Section: Nomenclaturementioning

confidence: 99%

Building towards a standardised approach to biocorrosion studies: a review of factors influencing Mg corrosion in vitro pertinent to in vivo corrosion

2017

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The factors that influence magnesium (Mg) corrosion in vitro are systematically evaluated from a review of the relevant literature. We analysed the influence of the following factors on Mg biocorrosion in vitro: (i) inorganic ions, including both anions and cations, (ii) organic components such as proteins, amino acids and vitamins, and (iii) experimental parameters such as temperature, pH, buffer system and flow rate. Considerations and recommendations towards a standardised approach to in vitro biocorrosion testing are given. Several potential simulated body fluids are recommended. Implementing a standardised approach to experimental parameters has the potential to significantly reduce variability between in vitro biocorrosion tests, and to help build towards a methodology that accurately and consistently mimics in vivo corrosion. However, there are also knowledge gaps with regard to how best to characterise the in vivo environment and corrosion mechanism. The assumption that blood plasma is the correct bodily fluid upon which to base in vitro methodologies is examined, and factors that influence the corrosion mechanism in vivo, such as specimen encapsulation, bear consideration for further studies.

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“…65 Typically, it has been well documented that Ag exerts broad-spectrum bactericidal activity against various microbes combined with a lower chance to evoke AMR because of its multiple target sites. [127][128][129] Furthermore, it can impart attractive dual catalytic/killing functions to endow the fast movement of MNMs and highly efficient bacteria-killing performance. For instance, Salvador and co-workers firstly designed magnetic Pd/Ni/Ag nanocoils with bactericidal properties by a directed electrodeposition method.…”

Section: Antibacterial Application Of Mnmsmentioning

confidence: 99%