1981
DOI: 10.1111/j.1600-0722.1981.tb01677.x
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Effect of chlorhexidine gel treatment on Streptococcus mutans population in human saliva and dental plaque

Abstract: – The effect of topical application of a 1% chlorhexidine gel on the population of S.mutains in dental plaque and saliva was studied in five subjects highly infected with the organism. After treatment for 5 min daily for 14 d, S. mutans was not detected in three of the subjects and counts of 700 colony‐forming units or less per ml of saliva were found in the other subjects. Reappearanceof S. mutans was slow and did not reach pretreatment level until 14 weeks or more after therapy. The proportion of S. saguis … Show more

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Cited by 76 publications
(104 citation statements)
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References 27 publications
(19 reference statements)
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“…Studies have shown that increasing CHX gel concentration from 1% to 5% does not increase its effect against SM [12] and most studies evaluating the use of the substance used concentration of 1% [12,17] In this study, the application of 1% CHX gel for 7 consecutive days caused the SM levels to remain very low and, in some cases, undetectable. These results are in agreement with previous studies [18,19] but in these papers, CHX gel was applied for a period of 14 days. The results of this study are important, as they certify that 1% CHX gel may be used daily for a shorter period of time, without interfering in its effectiveness.…”
Section: Discussionsupporting
confidence: 83%
“…Studies have shown that increasing CHX gel concentration from 1% to 5% does not increase its effect against SM [12] and most studies evaluating the use of the substance used concentration of 1% [12,17] In this study, the application of 1% CHX gel for 7 consecutive days caused the SM levels to remain very low and, in some cases, undetectable. These results are in agreement with previous studies [18,19] but in these papers, CHX gel was applied for a period of 14 days. The results of this study are important, as they certify that 1% CHX gel may be used daily for a shorter period of time, without interfering in its effectiveness.…”
Section: Discussionsupporting
confidence: 83%
“…Balanyk and Sandham [1985] demonstrated that in vitro chlorhexidine varnish was capable of releasing bactericidal levels of chlorhexidine continuously for up to 12 days. Short-term application of chlorhexidine gels and varnishes has also been shown to suppress S. mutans levels up to 3-4 months [Emilson, 1981;Maltz and Zickert, 1981;Schaeken et al, 1984;Zickert et al, 1982].…”
Section: Effect Of Chlorhexidine Varnish On Maternal S Mutans Levelsmentioning
confidence: 99%
“…Emilson (1981) published that CHX containing gel inhibited the plaque formation on tooth surfaces, effected on Gram positive and Gram negative bacteria such as mutans streptococci. CHX containing gel (e.g.…”
Section: Chlorhexidine Gelsmentioning
confidence: 99%