Effect of childhood maltreatment on cognitive function and its relationship with personality development and social coping style in major depression disorder patients: A latent class model and network analysis

Abstract

Study objectivesThe study aimed to (1) analyze the interrelationships among different types of childhood adversity, diverse personality dimensions, and individual coping style integratively among major depressive disorder (MDD) patients and healthy participants using a network approach; (2) explore the latent class of child maltreatment (CM) and its relationship with cognitive function.MethodsData were collected from the Objective Diagnostic Markers and Personalized Intervention in MDD Patients (ODMPIM) study, including 1,629 Chinese participants. Using the Childhood Trauma Questionnaire to assess CM, the Simplified Coping Style Questionnaire to measure individual coping style, Eysenck Personality Questionnaire Revised-Short Form for personality characters, and a series of neurocognitive tests, including seven tests with 18 subtests for cognitive assessments. We used the “Network Module” in Jeffreys’s Amazing Statistics Program (JASP) and R package for network analysis. A latent class analysis was performed with SAS9.4.ResultsChild maltreatment was more common in MDD patients than in healthy controls, except for emotional abuse. Network analysis showed that emotional abuse, emotional neglect, physical abuse, and physical neglect formed quadrangle connections. Personality dimensions were associated with physical neglect and emotional abuse. All types of CM (excluding sex abuse) showed an association with coping style. Emotional neglect showed the highest centrality measures. Physical neglect had a high level of closeness. To a concerning strength, emotional and physical neglect showed the highest levels. The structure of the networks is variant between groups (M = 0.28, P = 0.04). Latent class analysis (LCA) revealed that three classes provided the best fit statistics. Neglect and abuse classes tended to perform more poorly on the five cognitive domains.ConclusionThis study provided insights on multi-type of CM. Neglect played an important role in different routes through the relation between CM with personality traits and social coping style. However, neglect has often been ignored in previous studies and should receive more public attention.

Comparison of typical Thai and Hungarian personality profiles using the Zuckerman–Kuhlman–Aluja Personality Questionnaire

“…One cluster (half Thai–half Hungarian) was high in Extraversion (z = 0.68), but low in Aggression (z = −1.20), Neuroticism (z = −1.29) and Sensation seeking (z = −0.82). We named them ‘Resilients’, as they presented similar profile (high EX, low NE) to the Resilients of previous 22-country study of ZKA profiles 61 . The other profile, which we named as ‘Overcontrolled neurotic’, that had around equal number of Thai and Hungarian individuals, was low in Extraversion (z = −1.10), but definitely high in Neuroticism (z = 1.54) and moderately high in Aggression (z = 0.71).…”

“…We have applied analysis option of EBICGlasso with normalized centrality measure and tuning parameter of 0.50, using the R package ‘qgraph’ with ‘EBICglasso’ estimation 59 . Network invariance was tested by R package of ‘NetworkInvarianceTest’ 60 , 61 .…”

The role of only-child status in the effect of childhood trauma and parental rearing style on depressive symptoms in Shanghai adolescents

“…All these types of childhood trauma were related to adolescents’ depressive symptoms ( 21 ). Notably, as emotional trauma was more subtle, imperceptible, and lasting, emotional types of traumas had the strongest associations with depressive symptoms ( 22 , 23 ). Parental emotional neglect and abuse in childhood were associated with the formation of insecure attachments and emotional regulation strategies, which develop more depressive symptoms ( 24 ).…”