Effect of Chemotherapy on Health-Related Quality of Life among Early-Stage Ovarian Cancer Survivors: A Study from the Population-Based Profiles Registry

Bhugwandass, Celine; Pijnenborg, Johanna M.A.; Pijlman, Brenda; Ezendam, Nicole P. M.

doi:10.3747/co.23.3243

Cited by 22 publications

(12 citation statements)

References 27 publications

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“…As found in previous studies, patients who did not receive chemotherapy reported better global health scores compared with patients who underwent chemotherapy . This is conceivable given that the adverse effects of adjuvant chemotherapy may persist up to 1 year after treatment and only resolve later on .…”

Section: Discussionmentioning

confidence: 52%

“…As found in previous studies, patients who did not receive chemotherapy reported better global health scores compared with patients who underwent chemotherapy. 32 This is conceivable given that the adverse effects of adjuvant chemotherapy may persist up to 1 year after treatment and only resolve later on. 33,34 It has to be noted that the short-term and long-term side effects of chemotherapy may be alleviated by high-quality supportive care 35 including symptom management.…”

Section: Resultsmentioning

confidence: 99%

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Health‐related quality of life and psychological distress among cancer survivors in a middle‐income country

et al. 2018

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Section: Discussionmentioning

confidence: 52%

Section: Resultsmentioning

confidence: 99%

Health‐related quality of life and psychological distress among cancer survivors in a middle‐income country

et al. 2018

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“…Bhugwandass CS et al (2016) assessed differences in health-related quality of life between patients with early-stage ovarian cancer who did or did not receive chemotherapy as adjuvant treatment. They found that patients who receive adjuvant chemotherapy have a significantly worse score for 3 aspects of HRQOL [17].…”

Section: Discussionmentioning

confidence: 99%

Quality of Life of Patients With Ovarian Cancer of the Third Stage Using Differentiated Treatment

Рыбин

2017

EUREKA: Health Sciences

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The aim of this research was to assess the quality of life in patients with stage III ovarian cancer during the treatment period, depending on the applied therapeutic approaches. A comparative analysis of the results of treatment of 350 patients with adenocarcinoma of the ovaries of III-IV stage, which have undergone suboptimal or non-optimal cytomelective surgery, was conducted. To assess the quality of life and to examine the relationship between changes in physical health and quality of life, patients in both groups were asked to complete the questionnaires EORTC QLQ-C30 and SF-36. According to the questionnaire of the EORTC QLQ-C30, the indicators of physical activity, the ability to do everyday affairs, were higher in the second group of patients who received differentiated treatment. The indicator of "social functioning" was also higher in the II group of patients. When evaluating the patients' liver on the scale of the questionnaire SF-36, it was found that the positive effect of differentiated therapy is maintained for 3 years. Life quality is an important criterion for evaluating the results of antitumor therapy, and when it is continuously monitored in patients with ovarian cancer the safety of treatment for patients could be improved, including at an advanced stage

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“…All these agents cause serious side effects [3] [4] [5], which includes kidney, liver, nerve and blood vessel damage, hearing loss, lower blood count etc. [6] [7], regional toxicity affecting mucosa cells, causing irritative urinary and blood loss [7]. Later toxic effects include damage to proliferating cells such as fibroblasts, endothelial and parenchymal cells [7].…”

Section: Conventional Cancer Therapymentioning

confidence: 99%

“…Later toxic effects include damage to proliferating cells such as fibroblasts, endothelial and parenchymal cells [7]. Other undesired side effects such as immune suppression, bone necrosis, lung fibrosis and skin devascularization are seen with all conventional therapies [5] [6] [7] [8]. Although the desired goal of chemotherapy is to eliminate the tumor cells, diverse range of normal cells is also affected, leading to many adverse side effects on multiple organ systems [9]- [14].…”

Section: Conventional Cancer Therapymentioning

confidence: 99%

Naturally Derived Formulations and Prospects towards Cancer

Masarkar¹,

Mukherjee²,

Goel³

et al. 2019

Health

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Traditional Medicine (TM) and their secondary metabolites are being increasingly recognized as useful complementary treatments toward the cancer. A large number of clinical studies have reported and proven concern of cancer patients. Here we have also reported recent studies on the biochemical and cellular mechanisms of Traditional Medicine (TM). Nowadays, Chemotherapy and surgery are standard methods for treatment of cancer, but still it's not been fully successful. Some progress has been made in cancer diagnosis and treatment, but high incidence rate of cancer and low survival rate of patient are still being reported worldwide. Since ancient times, a number of traditional medicines known as Ayurveda, Siddha, Unani, Iranian, Chinese, Korean, acupuncture, Muti, Ifa, and African medicine are widely used for therapeutic purposes and are becoming popular as Traditional Medicine (TM). It has been reported that plants synthesize plethora of "secondary metabolites" or "phytochemicals", proven to possess anti-mutagenic and anti-cancer properties in many research studies. There are many possibilities for further organized research for screening of medicinal plants for their potential and efficacy against chronic diseases such as a cancer and other inflammatory diseases. Therefore, researcher's interest should be in identification and standardization of new anti-cancer drug with low side effects and greater efficacy, that is easily acceptable in medical community and which may overcome the challenges in present and future cancer therapy. This review explores therapeutic value of certain bio-active principals of plant which could serve as potential pharmacologically active drug for treatment of cancer in future.

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Effect of Chemotherapy on Health-Related Quality of Life among Early-Stage Ovarian Cancer Survivors: A Study from the Population-Based Profiles Registry

Abstract: Background There is wide variation in the application of adjuvant chemotherapy in early-stage epithelial ovarian

Cited by 22 publications

References 27 publications

Health‐related quality of life and psychological distress among cancer survivors in a middle‐income country

Health‐related quality of life and psychological distress among cancer survivors in a middle‐income country

Quality of Life of Patients With Ovarian Cancer of the Third Stage Using Differentiated Treatment

Naturally Derived Formulations and Prospects towards Cancer

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