Effect of Chemical Disinfection on Chitosan Coated PMMA and PETG Surfaces—An In Vitro Study

Abstract

Abstract:In oral sciences, chitosan application is of interest due to its antimicrobial and hemostatic activity. Chitosan coating of dentures and other intraoral devices could be beneficial for treatment of denture stomatitis or in the management of postoperative bleeding. Disinfection of dentures and prosthodontic materials is crucial before their use in patients. This study investigated the influence of chemical disinfectants on chitosan-coated surfaces. A total of 100 specimens were made: 50 of PMMA (polymethyl methacrylate), and 50 of PETG (polyethylene terephthalate glycol-modified) material and coated with 2% chitosan acetate solution. In each material, 5 groups (10 specimens each) were established and disinfected with Printosept-ID (L1), MD 520 (L2), Silosept (L3), or Dentavon (L4), or stored in distilled water (L0, control group). After disinfection, all specimens underwent abrasion tests (30,000 cycles in a tooth-brushing simulator). Areas without chitosan coating were measured by digital planimetry both before and after the disinfection/abrasion procedure and a damage-score was calculated. Regarding chitosan coating, the statistical analysis showed a significant influence of the disinfectants tested and significant differences between disinfectants (p < 0.05). Chitosan coating was most stable on PMMA and PETG after disinfection with MD 520 (L2). Otherwise, active oxygen containing disinfectants (L3, L4) led to the greatest alterations in the chitosan coating.

Surface Quality Evaluation of Removable Thermoplastic Dental Appliances Related to Staining Beverages and Cleaning Agents

“…Factors like material characteristics, exposure of these in the oral environment, and parameters of thermoforming, are found to contribute to the roughness of the PET-G materials [ 26 , 27 , 28 ]. It is known that the mean roughness (Ra) of dental materials should be below 0.2 µm in order to prevent the accumulation of plaque and microorganisms [ 29 , 30 , 31 ]. An increase in surface roughness leads to an increase plaque accumulation over time [ 32 ].…”

Novel modalities of delivering herbal medicines for wound healing: A review

“…A total of 2% CS acetate solution is used as a coating material. The CS coating was more stable after disinfection on PMMA and Polyethylene terephthalate glycol (PETG) 131 . The goal of the 132 study was to evaluate the efficacy of low‐molecular‐weight CS solutions against Candida albicans biofilm on PMMA resin.…”

“…Both types of CS solutions, as well as 30 kDa CS solution and 3 and 6 mg/ml of oligomer CS, were powerful antifungal denture cleansers that greatly decreased the survival of C. Albicans in biofilm on PMMA 132 . The layer‐by‐layer (LbL) self‐assembly method used in the 131 study focused on a local Icariin (ICA) transport system of a phase‐transited lysozyme (PTL)‐primed Ti surface. A PTL nanofilm was initially applied to the virgin Ti.…”

“…According to the current research, an ICA‐immobilized HA/CS multilayer over a PTL‐primmed Ti surface exhibited a protracted ICA release pattern, which may stimulate osteoblast osteogenesis in vitro and enhance early osseointegration in vivo. This study presents a novel method for constructing a long‐term ICA delivery system that increases osseointegration and osteoblast response 131 . Enkatraman and Chander 133 investigated how varying Ch concentrations affected the heat‐polymerized denture base resin's (DBR) fracture toughness (FT), flexural strength (FS), surface roughness (Ra), and impact strength (IS).…”

“…The CS coating was more stable after disinfection on PMMA and Polyethylene terephthalate glycol (PETG). 131 The goal of the 132 study was to evaluate the efficacy of low-molecular-weight CS solutions against Candida albicans biofilm on PMMA resin. Different CS kinds were examined for anti-Candida action by broth dilution.…”