Effect of changing the age criteria for blood donors

Goldman, Mindy; Fournier, E.; Cameron-Choi, Keltie; Steed, Tony

doi:10.1111/j.1423-0410.2007.00897.x

Cited by 27 publications

(44 citation statements)

References 14 publications

(16 reference statements)

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“…We do not consider this recommendation by the family doctor as necessary as long as each single donation is preceded by a consultation with the attending donor center physician. This is in line with the assessment of Goldman et al [3] who got the approval of the family doctors of 98% of contacted donors belonging to the age group of the 70- to 74-year-olds. …”

Section: Discussionsupporting

confidence: 66%

“…In the meantime there have been various studies on the safety of blood donations with regard to aged donors [3,5,6,7,13,19]. However, up to now these studies - including our own preceding study [11] - were carried out at selected or limited donation appointments.…”

Section: Discussionmentioning

confidence: 99%

“…At that time data published on the incidence rate did comprise donors up to the age of 71 years [13], and it was only later that records on donors over the age of 71 years became available [3]. This is why, when we raised the upper age limit up to the completed age of 71 years, it was only within the scope of a prospective study.…”

Section: Discussionmentioning

confidence: 99%

“…Donor reactions were classified identical to our previous study [11] as mild, moderate, or severe following a modified version of the definitions published by the Canadian Blood Services [13] and others [3,14] including systemic reactions as well as donor injuries and continued medical treatment:…”

Section: Methodsmentioning

confidence: 99%

“…exclusion in case of specific infectious diseases), the reasons for deferral to protect the donor are sometimes arbitrary due to the lack of objective data [1,2]. This applies in particular to donors reaching the upper age limit which does not only differ from nation to nation but also within individual countries [3]. The various aspects of the eligibility of older donors have been discussed previously [4,5,6,7].…”

Section: Introductionmentioning

confidence: 99%

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Blood Donation by Elderly Repeat Blood Donors

Zeiler

Lander-Kox

Alt

2014

Transfus Med Hemother

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Background: Upper age limits for blood donors are intended to protect elderly blood donors from donor reactions. However, due to a lack of data about adverse reactions in elderly blood donors, upper age limits are arbitrary and vary considerably between different countries. Methods: Here we present data from 171,231 voluntary repeat whole blood donors beyond the age of 68 years. Results: Blood donations from repeat blood donors beyond the age of 68 years increased from 2,114 in 2005 to 38,432 in 2012 (from 0,2% to 4.2% of all whole blood donations). Adverse donor reactions in repeat donors decreased with age and were lower than in the whole group (0.26%), even in donors older than 71 years (0.16%). However, from the age of 68 years, the time to complete recovery after donor reactions increased. Donor deferrals were highest in young blood donors (21.4%), but increased again in elderly blood donors beyond 71 years (12.6%). Conclusion: Blood donation by regular repeat blood donors older than 71 years may be safely continued. However, due to a lack of data for donors older than 75 years, blood donation in these donors should be handled with great caution.

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Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Blood Donation by Elderly Repeat Blood Donors

Zeiler

Lander-Kox

Alt

2014

Transfus Med Hemother

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Evidence‐based selection criteria to protect blood donors

Eder

2010

J of Clinical Apheresis

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A safe and adequate blood supply depends on healthy, volunteer blood donors. Blood centers have instituted various screening procedures in an effort to determine that donors are free of diseases that can be transmitted to patients by blood transfusion and are able to tolerate the collection procedure without experiencing significant complications. This review focuses on selection criteria intended to minimize the risk to the blood donor. Defining a rational, evidence-based approach to donor selection is crucial not only to take reasonable precautions to protect the donors' health but also to eliminate practices that lead to the unnecessary deferral of large numbers of people without improving the safety of the donation process. Donor selection criteria, including predonation pulse and blood pressure, donor weight and total blood volume, minimum hemoglobin and donation interval, are considered against the available evidence that support or suggest the need to modify the current approach to protect blood donor health.

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