Effect of Change in Portal Venous Blood Flow Rates on the Performance of a 2.45-GHz Microwave Ablation Device

Objectives The aim of the present study is to analyze preclinical and clinical data on the performance of the currently US Food and Drug Administration (FDA)–approved microwave ablation (MWA) systems. Methods A review of the literature, published between January 1, 2005, and December 31, 2016, on seven FDA-approved MWA systems, was conducted. Ratio of ablation zone volume to applied energy R(AZ:E) and sphericity indices were calculated for ex vivo and in vivo experiments. Results Thirty-four studies with ex vivo, in vivo, and clinical data were summarized. In total, 14 studies reporting data on ablation zone volume and applied energy were included for comparison R(AZ:E). A significant correlation between volume and energy was found for the ex vivo experiments ( r = 0.85, p < 0.001) in contrast to the in vivo experiments ( r = 0.54, p = 0.27). Conclusion Manufacturers’ algorithms on microwave ablation zone sizes are based on preclinical animal experiments with normal liver parenchyma. Clinical data reporting on ablation zone volume in relation to applied energy and sphericity index during MWA are scarce and require more adequate reporting of MWA data. Key Points • Clinical data reporting on the ablation zone volume in relation to applied energy during microwave ablation are scarce. • Manufacturers’ algorithms on microwave ablation zone sizes are based on preclinical animal experiments with normal liver parenchyma. • Preclinical data do not predict actual clinical ablation zone volumes in patients with liver tumors.

show abstract

Liver microwave ablation: a systematic review of various FDA-approved systems

Ruiter

Heerink

Jong

2018

Eur Radiol

View full text Add to dashboard Cite

show abstract

Combination Therapies: Quantifying the Effects of Transarterial Embolization on Microwave Ablation Zones

Knavel

Green

Gendron‐Fitzpatrick

et al. 2018

Journal of Vascular and Interventional Radiology

View full text Add to dashboard Cite

Microwave ablation using two simultaneous antennas for the treatment of liver malignant lesions: a 3 year single-Centre experience

Andresciani

Grasso

Vertulli

et al. 2023

International Journal of Hyperthermia

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Effect of Change in Portal Venous Blood Flow Rates on the Performance of a 2.45-GHz Microwave Ablation Device

Abstract: Change in portal venous blood flow rates did not have an effect on the size and shape of ablations created by a 2.45-GHz microwave ablation device.

Cited by 5 publications

References 34 publications

Liver microwave ablation: a systematic review of various FDA-approved systems

Liver microwave ablation: a systematic review of various FDA-approved systems

Combination Therapies: Quantifying the Effects of Transarterial Embolization on Microwave Ablation Zones

Microwave ablation using two simultaneous antennas for the treatment of liver malignant lesions: a 3 year single-Centre experience

Contact Info

Product

Resources

About