“…The emergence of additive manufacturing has extended the application of Voronoi tessellation from mere analysis to the generation of 3D scaffolds, i.e., Voronoi structures with mesh wrapped around the wireframes. Voronoi scaffolds have been 3D printed as supports for hollow objects 19 , interlocking architecture 20 , optimal lightweight structures [21][22][23] , patient specific bone scaffolds 24,25 , for surgical practice 26 , for patient education of upcoming procedures 27 , regenerative medicine and wound healing techniques 28 , implantable drug delivery 29 and T-cell culturing environments 14 .…”