Effect of Cedrus deodara (Pinaceae) Root Oil on the Histopathology of Rat Liver and Kidney

Parveen, Rehana; Azmi, M. Arshad; Naqvi, Syed Naeemul Hassan; Mahmood, Syed Mohammad; Zaidi, None Ijaz Hussain

doi:10.4314/tjpr.v9i2.53699

Cited by 9 publications

(5 citation statements)

References 9 publications

(11 reference statements)

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“…EOs at high doses caused acute toxicity, ardiovascular and respiratory toxicity, genotoxicity, abortifacient activity in rabbits and rats (European Medicines Agency, 2010). It also has been reported that root EO of C. deodara when orally given may harm the liver and kidney tissues of Wistar rats (Parveen, Azmi, Naqvi, Mahmood, & Zaldi, 2010).…”

Section: Toxicological Status Of Conifers Eosmentioning

confidence: 99%

Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

Bhardwaj

Islam

Jayasena

et al. 2020

Phytotherapy Research

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Essential oils (EOs) are regarded as alternative therapeutic agents for many diseases. In phytotherapy research areas, it is now well reported that conifers are the rich source of EOs. This review aims to update information on the biological sources and the best extraction processes of the significant constituents along with the traditional and therapeutic properties of the EOs from selected conifers of Himachal Pradesh, Northwestern Himalaya. In the present review, ten conifer species of high values have been selected. Results from several studies suggest that the conifers contain monoterpenes, sesquiterpenes, diterpenes, ketones, alcohols, and esters, which are used in medicines, food products, and cosmetics as well as other commercial and industrial products. Traditionally, the EOs from the conifers have been reported to be used against fever, cough, bronchitis, skin diseases, gastrointestinal disorders, and asthma. The pharmacological studies suggest that these EOs can be used as antirheumatic, antiseptic, antispasmodic, anticancer, anti-inflammatory, antitoxic, aphrodisiac, and astringent agents. It is, therefore, concluded that the EOs from the conifers might be one of the promising tools for the treatment of various diseases. Extensive research is required to ascertain the efficacy of the EOs from unstudied conifers.

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Section: Toxicological Status Of Conifers Eosmentioning

confidence: 99%

Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

Bhardwaj

Islam

Jayasena

et al. 2020

Phytotherapy Research

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“…For a branch and leaf EO of C. atlantica , an LD50 of 500 mg/kg was estimated in rats after a single dose administration [ 90 ]. At a dose of 2.5 mL/rat, a C. deodara root oil caused a number of modifications in the liver and kidney of the animals (fatty changes, some congestion and a few inflammatory cells in the liver, atrophic changes, slight edema and inflammatory cells in the kidney) [ 288 ].…”

Section: Pharmacological Interest Of Pinaceae Eosmentioning

confidence: 99%

Antioxidant Activity of Essential Oils from Pinaceae Species

Ancuceanu,

Anghel,

Hovaneț

et al. 2024

Antioxidants

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With a widespread distribution throughout the Northern Hemisphere and 11 genera, Pinaceae is the largest family of Gymnosperms in the world. Essential oils are an important chemotaxonomic marker for the species of this family, although the degree of chemical and biological investigation has not been the same for all genera. Essential oils from Abies and Cedrus (from the abietoid clade) or Pinus and Picea (from the pinoid clade) have been more extensively investigated with respect to their chemical composition and biological or pharmacological properties, including their antioxidant effects. Instead, essential oils from the other genera of the family have been less explored in this respect or even have not been investigated at all. This is a narrative review looking into the knowledge acquired up to date, the variability and limitations of the current methods used to estimate antioxidant effects, and multiple comparisons between EOs obtained from different genera, species, and plant parts, as well as potential applications and future directions of research and utilization of essential oils derived from Pinaceae species.

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“…Literature have revealed the various pharmacological activities of the tree and its oil like antibacterial, insecticidal activity, Molluscidal activity, antitubercular activity, anxiolytic and anticonvulsant activity, neuroleptic activity, antidiabetic activity, antioxidant activity, antimalarial activity and cytotoxic activity [33][34][35][36][37][38][39][40][41][42][43][44][45][46][47] .…”

Section: Pharmacological Activitymentioning

confidence: 99%

A Review on Siddha Herbal Formulation Deva Chooranam for Improving the Qol in Acquired Immuno Deficiency Syndrome (Aids)

Thangadurai¹

2017

WJPR

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Effect of Cedrus deodara (Pinaceae) Root Oil on the Histopathology of Rat Liver and Kidney

Cited by 9 publications

References 9 publications

Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

Review on essential oils, chemical composition, extraction, and utilization of some conifers in Northwestern Himalayas

Antioxidant Activity of Essential Oils from Pinaceae Species

A Review on Siddha Herbal Formulation Deva Chooranam for Improving the Qol in Acquired Immuno Deficiency Syndrome (Aids)

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