Abstract:
Purpose: To study the effect of CBX4/miR-137/Notch1 signaling axis on the migration and proliferative capacity of breast cancer.
Methods: Breast cancer MCF7 cell lines were cultured in vitro and transfected with CBX4- overexpressed plasmid and interfering plasmid, which served as CBX4 over-expressing group and CBX4 interfering group, respectively. A control group (blank plasmid transfection) was set up. The MCF7 cells were transfected with miR-137 over-expressed plasmid, miR-1… Show more
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